| A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ... Nature medicine 18 (4), 521-528, 2012 | 683 | 2012 |
| Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins KP Ng, G Potikyan, ROV Savene, CT Denny, VN Uversky, KAW Lee Proceedings of the National Academy of Sciences 104 (2), 479-484, 2007 | 120 | 2007 |
| Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition KP Ng, A Manjeri, KL Lee, W Huang, SY Tan, CTH Chuah, L Poellinger, ... Blood, The Journal of the American Society of Hematology 123 (21), 3316-3326, 2014 | 103 | 2014 |
| The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors TK Ko, CTH Chuah, JWJ Huang, KP Ng, ST Ong Oncotarget 5 (19), 9033, 2014 | 71 | 2014 |
| An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia TK Ko, A Javed, KL Lee, TN Pathiraja, X Liu, S Malik, SX Soh, XT Heng, ... Blood, The Journal of the American Society of Hematology 135 (26), 2337-2353, 2020 | 67 | 2020 |
| Rapid production of clinical‐grade SARS‐CoV‐2 specific T cells W Leung, TG Soh, YC Linn, JGH Low, J Loh, M Chan, WJ Chng, LP Koh, ... Advances in cell and gene therapy 3 (4), e101, 2020 | 28 | 2020 |
| The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia TK Ko, H San Chin, CTH Chuah, JWJ Huang, KP Ng, SL Khaw, ... Oncotarget 7 (3), 2721, 2015 | 23 | 2015 |
| The arginase inhibitor Nω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 … KP Ng, A Manjeri, LM Lee, ZE Chan, CY Tan, QD Tan, AQ Majeed, ... PLoS One 13 (10), e0205254, 2018 | 15 | 2018 |
| The RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell lines Y Zhao, KKC Li, KP Ng, CH Ng, KAW Lee Protein & cell 3 (11), 846-854, 2012 | 15 | 2012 |
| RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct BL Chau, KP Ng, KKC Li, KAW Lee Transcription 7 (4), 141-151, 2016 | 11 | 2016 |
| In vitro activity of the EWS oncogene transcriptional activation domain KP Ng, KKC Li, KAW Lee Biochemistry 48 (13), 2849-2857, 2009 | 8 | 2009 |
| Human bone xenografts: from preclinical testing for regenerative medicine to modeling of diseases MSK Chong, C Bao, KP Ng, J Lim, JKY Chan Current Molecular Biology Reports 2, 158-170, 2016 | 7 | 2016 |
| A transcription assay for EWS oncoproteins in Xenopus oocytes KP Ng, F Cheung, KAW Lee Protein & cell 1 (10), 927-934, 2010 | 4 | 2010 |
| SUCCESSFUL MANUFACTURING OF CLINICAL-GRADE SARS-CoV-2 SPECIFIC T CELLS FOR ADOPTIVE CELL THERAPY W Leung, TG Soh, YC Linn, JGH Low, J Loh, M Chan, WJ Chng, LP Koh, ... medRxiv, 2020.04. 24.20077487, 2020 | 3 | 2020 |
| The genomic and epigenomic landscapes of blast crisis transformation in chronic myeloid leukemia ST Ong, T Pathiraja, A Javed, XXS Soh, S Malik, JHJ Tan, TK Ko, ... Blood, The Journal of the American Society of Hematology 126 (23), 3737-3737, 2015 | 3 | 2015 |
| The BIM deletion polymorphism: a paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia TK Ko, C Chuah, JWJ Huang, KP Ng, ST Ong Blood 122 (21), 3977, 2013 | 2 | 2013 |
| Physiologic Hypoxia Protects Chronic Myelogenous Leukemia Progenitors From Elimination by Imatinib Mesylate. KP Ng, TY Poh, WT Sun, C Chuah, ST Ong Blood 114 (22), 2181, 2009 | 2 | 2009 |
| Method of detecting resistance to cancer therapy Y Ruan, ST Ong, KP Ng, CTH Chuah, AM Hillmer, WC Juan US Patent App. 13/993,745, 2013 | 1 | 2013 |
| The BCL-2 Inhibitor ABT-199 Enhances Imatinib-Induced Cell Death In Chronic Phase CML Progenitors TK Ko, C Chuah, J Huang, KP Ng, ST Ong Blood 122 (21), 3978, 2013 | 1 | 2013 |
| A Common Deletion Polymorphism in the BIM Gene Contributes to Intrinsic Imatinib Resistance in Chronic Myelogenous Leukemia AM Hillmer, KP Ng, C Chuah, WC Juan, TK Ko, ASM Teo, PN Ariyaratne, ... Blood 118 (21), 1666, 2011 | 1 | 2011 |
