Synthesis of Boron Nitride Nanotubes by Means of Excimer Laser Ablation at High Temperature ZFDZZ 27. D.P.Yu, X.S.Sun, C.S.Lee, I.Bello, S.T.Lee, H.D.Gu, K.M.Leung, G.W ... Applied Physics Letters 71 (16), 1966, 1998 | 339* | 1998 |
Selecting the correct weighting factors for linear and quadratic calibration curves with least-squares regression algorithm in bioanalytical LC-MS/MS assays and impacts of … H Gu, G Liu, J Wang, AF Aubry, ME Arnold Analytical Chemistry 86 (18), 8959-8966, 2014 | 249 | 2014 |
Multicenter, randomized, double-blind, placebo-controlled, single-ascending dose study of the oral γ-secretase inhibitor BMS-708163 (Avagacestat): tolerability profile … G Tong, JS Wang, O Sverdlov, SP Huang, R Slemmon, R Croop, ... Clinical therapeutics 34 (3), 654-667, 2012 | 93 | 2012 |
Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC–MS/MS approach: assay development, validation, and a case study A Liu, A Kozhich, D Passmore, H Gu, R Wong, F Zambito, VS Rangan, ... Journal of Chromatography B 1002, 54-62, 2015 | 68 | 2015 |
Validated LC–MS/MS methods for the determination of dapagliflozin, a sodium-glucose co-transporter 2 inhibitor in normal and ZDF rat plasma AF Aubry, H Gu, R Magnier, L Morgan, X Xu, M Tirmenstein, B Wang, ... Bioanalysis 2 (12), 2001-2009, 2010 | 59 | 2010 |
A placebo-controlled, multiple ascending dose study to evaluate the safety, pharmacokinetics and pharmacodynamics of avagacestat (BMS-708163) in healthy young and elderly subjects R Dockens, JS Wang, L Castaneda, O Sverdlov, SP Huang, R Slemmon, ... Clinical pharmacokinetics 51, 681-693, 2012 | 55 | 2012 |
Effects of single doses of avagacestat (BMS-708163) on cerebrospinal fluid Aβ levels in healthy young men G Tong, L Castaneda, JS Wang, O Sverdlov, SP Huang, R Slemmon, ... Clinical drug investigation 32, 761-769, 2012 | 48 | 2012 |
Practical and efficient strategy for evaluating oral absolute bioavailability with an intravenous microdose of a stable isotopically-labeled drug using a selected reaction … H Jiang, J Zeng, W Li, M Bifano, H Gu, C Titsch, J Easter, R Burrell, ... Analytical chemistry 84 (22), 10031-10037, 2012 | 46 | 2012 |
Antibody–drug conjugate bioanalysis using LB-LC–MS/MS hybrid assays: Strategies, methodology and correlation to ligand-binding assays J Wang, H Gu, A Liu, A Kozhich, V Rangan, H Myler, L Luo, R Wong, ... Bioanalysis 8 (13), 1383-1401, 2016 | 43 | 2016 |
Effects of sub-chronic donepezil on brain Abeta and cognition in a mouse model of Alzheimer’s disease A Easton, S Sankaranarayanan, A Tanghe, D Terwel, AX Lin, N Hoque, ... Psychopharmacology 230, 279-289, 2013 | 43 | 2013 |
Calculation and mitigation of isotopic interferences in liquid chromatography–mass spectrometry/mass spectrometry assays and its application in supporting microdose absolute … H Gu, J Wang, AF Aubry, H Jiang, J Zeng, J Easter, J Wang, R Dockens, ... Analytical chemistry 84 (11), 4844-4850, 2012 | 41 | 2012 |
Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in … R Demers, H Gu, LJ Christopher, H Su, L Cojocaru, DW Boulton, M Kirby, ... Journal of Chromatography B 889, 77-86, 2012 | 41 | 2012 |
Effect of mobile phase pH, aqueous‐organic ratio, and buffer concentration on electrospray ionization tandem mass spectrometric fragmentation patterns: implications in liquid … J Wang, A Aubry, MS Bolgar, H Gu, TV Olah, M Arnold, M Jemal Rapid Communications in Mass Spectrometry 24 (22), 3221-3229, 2010 | 41 | 2010 |
An integrated multiplatform bioanalytical strategy for antibody–drug conjugates: a novel case study H Myler, VS Rangan, J Wang, A Kozhich, JA Cummings, R Neely, D Dail, ... Bioanalysis 7 (13), 1569-1582, 2015 | 40 | 2015 |
Room-temperature growth of high-purity titanium nitride by laser ablation of titanium in a nitrogen atmosphere HD Gu, KM Leung, CY Chung, XD Han Surface and Coatings Technology 110 (3), 153-157, 1998 | 34 | 1998 |
Pulsed laser deposition of NiTi shape memory alloy thin films with optimum parameters HD Gu, KM Leung, CY Chung, L You, XD Han, KS Chan, JKL Lai Thin Solid Films 330 (2), 196-201, 1998 | 33 | 1998 |
Growth of TiNiHf shape memory alloy thin films by laser ablation of composite targets HD Gu, L You, KM Leung, CY Chung, KS Chan, JKL Lai Applied surface science 127, 579-583, 1998 | 31 | 1998 |
BMS-708163, a potent and selective γ-secretase inhibitor, decreases CSF Aβ at safe and tolerable doses in animals and humans CF Albright, R Dockens, RE Olson, J Meredith, R Slemmon, K Lentz, ... International Conference on Alzheimer’s Disease, 26-31, 2008 | 30 | 2008 |
Development and validation of sensitive and selective LC–MS/MS methods for the determination of BMS-708163, a γ-secretase inhibitor, in plasma and cerebrospinal fluid using … H Gu, Y Deng, J Wang, AF Aubry, ME Arnold Journal of Chromatography B 878 (25), 2319-2326, 2010 | 29 | 2010 |
Immunoaffinity LC–MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker H Zhang, H Gu, P Shipkova, E Ciccimaro, H Sun, Q Zhao, TV Olah Bioanalysis 9 (20), 1573-1588, 2017 | 25 | 2017 |