| AMPAR removal underlies Aβ-induced synaptic depression and dendritic spine loss H Hsieh, J Boehm, C Sato, T Iwatsubo, T Tomita, S Sisodia, R Malinow Neuron 52 (5), 831-843, 2006 | 1335 | 2006 |
| Tau kinetics in neurons and the human central nervous system C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ... Neuron 97 (6), 1284-1298. e7, 2018 | 541 | 2018 |
| A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease NR Barthélemy, Y Li, N Joseph-Mathurin, BA Gordon, J Hassenstab, ... Nature medicine 26 (3), 398-407, 2020 | 435 | 2020 |
| Notch signaling in the regulation of stem cell self-renewal and differentiation J Liu, C Sato, M Cerletti, A Wagers Current topics in developmental biology 92, 367-409, 2010 | 385 | 2010 |
| Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease NR Barthélemy, K Horie, C Sato, RJ Bateman Journal of Experimental Medicine 217 (11), e20200861, 2020 | 324 | 2020 |
| C-terminal fragment of presenilin is the molecular target of a dipeptidic γ-secretase-specific inhibitor DAPT (N-[N-(3, 5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl … Y Morohashi, T Kan, Y Tominari, H Fuwa, Y Okamura, N Watanabe, ... Journal of Biological Chemistry 281 (21), 14670-14676, 2006 | 226 | 2006 |
| Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification NR Barthélemy, RJ Bateman, C Hirtz, P Marin, F Becher, C Sato, ... Alzheimer's research & therapy 12, 1-11, 2020 | 175 | 2020 |
| Structure of the catalytic pore of γ-secretase probed by the accessibility of substituted cysteines C Sato, Y Morohashi, T Tomita, T Iwatsubo Journal of Neuroscience 26 (46), 12081-12088, 2006 | 173 | 2006 |
| The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the γ-secretase C Sato, S Takagi, T Tomita, T Iwatsubo Journal of Neuroscience 28 (24), 6264-6271, 2008 | 170 | 2008 |
| Pen-2 is incorporated into the γ-secretase complex through binding to transmembrane domain 4 of presenilin 1 N Watanabe, T Tomita, C Sato, T Kitamura, Y Morohashi, T Iwatsubo Journal of Biological Chemistry 280 (51), 41967-41975, 2005 | 141 | 2005 |
| Tau phosphorylation rates measured by mass spectrometry differ in the intracellular brain vs. extracellular cerebrospinal fluid compartments and are differentially affected by … NR Barthélemy, N Mallipeddi, P Moiseyev, C Sato, RJ Bateman Frontiers in aging neuroscience 11, 121, 2019 | 125 | 2019 |
| CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease K Horie, NR Barthélemy, C Sato, RJ Bateman Brain 144 (2), 515-527, 2021 | 101 | 2021 |
| Presenilin: RIP and beyond MR Hass, C Sato, R Kopan, G Zhao Seminars in cell & developmental biology 20 (2), 201-210, 2009 | 99 | 2009 |
| TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading Y Xu, S Du, JA Marsh, K Horie, C Sato, A Ballabio, CM Karch, ... Molecular Psychiatry 26 (10), 5925-5939, 2021 | 88 | 2021 |
| Aβ42 overproduction associated with structural changes in the catalytic pore of γ-secretase: common effects of Pen-2 N-terminal elongation and fenofibrate N Isoo, C Sato, H Miyashita, M Shinohara, N Takasugi, Y Morohashi, ... Journal of biological chemistry 282 (17), 12388-12396, 2007 | 82 | 2007 |
| An overview of notch signaling in adult tissue renewal and maintenance C Sato, G Zhao, XG Ilagan Current Alzheimer Research 9 (2), 227-240, 2012 | 72 | 2012 |
| Participation of transmembrane domain 1 of presenilin 1 in the catalytic pore structure of the γ-secretase S Takagi, A Tominaga, C Sato, T Tomita, T Iwatsubo Journal of Neuroscience 30 (47), 15943-15950, 2010 | 69 | 2010 |
| CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease K Horie, G Salvadó, NR Barthélemy, S Janelidze, Y Li, Y He, B Saef, ... Nature medicine 29 (8), 1954-1963, 2023 | 52 | 2023 |
| SILK studies—capturing the turnover of proteins linked to neurodegenerative diseases RW Paterson, A Gabelle, BP Lucey, NR Barthélemy, CA Leckey, C Hirtz, ... Nature Reviews Neurology 15 (7), 419-427, 2019 | 47 | 2019 |
| CSF tau microtubule-binding region identifies pathological changes in primary tauopathies K Horie, NR Barthélemy, S Spina, L VandeVrede, Y He, RW Paterson, ... Nature medicine 28 (12), 2547-2554, 2022 | 42 | 2022 |
Randall BatemanWashington University in St. Louis在 wustl.edu 的电子邮件经过验证
