Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library H Koike-Yusa, Y Li, EP Tan, MDC Velasco-Herrera, K Yusa Nature biotechnology 32 (3), 267-273, 2014 | 1240 | 2014 |
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors MD Young, TJ Mitchell, FA Vieira Braga, MGB Tran, BJ Stewart, ... science 361 (6402), 594-599, 2018 | 596 | 2018 |
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo FA Karreth, M Reschke, A Ruocco, C Ng, B Chapuy, V Léopold, ... Cell 161 (2), 319-332, 2015 | 334 | 2015 |
Spatiotemporal immune zonation of the human kidney BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ... Science 365 (6460), 1461-1466, 2019 | 328 | 2019 |
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization L van der Weyden, MJ Arends, AD Campbell, T Bald, H Wardle-Jones, ... Nature 541 (7636), 233-236, 2017 | 210 | 2017 |
Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations M Iovino, S Agathou, A González-Rueda, M Del Castillo Velasco-Herrera, ... Brain 138 (11), 3345-3359, 2015 | 151 | 2015 |
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis F Penkava, MDC Velasco-Herrera, MD Young, N Yager, LN Nwosu, ... Nature communications 11 (1), 4767, 2020 | 129 | 2020 |
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells TI Roumeliotis, SP Williams, E Goncalves, M Del Castillo Velasco-Herrera, ... Cell Reports 20 (9), 2201 - 2214, 2017 | 117 | 2017 |
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome RE McIntyre, P Lakshminarasimhan Chavali, O Ismail, DM Carragher, ... PLoS genetics 8 (11), e1003022, 2012 | 102 | 2012 |
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants J Wegert, C Vokuhl, G Collord, M Del Castillo Velasco-Herrera, ... Nature communications 9 (1), 2378, 2018 | 88 | 2018 |
Off‐target assessment of CRISPR‐C as9 guiding RNA s in human i PS and mouse ES cells EP Tan, Y Li, M Del Castillo Velasco‐Herrera, K Yusa, A Bradley genesis 53 (2), 225-236, 2015 | 84 | 2015 |
Combinatorial CRISPR screen identifies fitness effects of gene paralogues NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, ... Nature communications 12 (1), 1302, 2021 | 77 | 2021 |
Revisiting olfactory receptors as putative drivers of cancer M Ranzani, V Iyer, X Ibarra-Soria, MDC Velasco-Herrera, M Garnett, ... Wellcome open research 2, 2017 | 51 | 2017 |
Telomere-regulating genes and the telomere interactome in familial cancers CD Robles-Espinoza, M del Castillo Velasco-Herrera, NK Hayward, ... Molecular cancer research 13 (2), 211-222, 2015 | 41 | 2015 |
GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer A Checa-Rojas, LF Delgadillo-Silva, M del Castillo Velasco-Herrera, ... Oncotarget 9 (31), 21696, 2018 | 38 | 2018 |
Reconstructing and mining the B cell repertoire with ImmunediveRsity B Cortina-Ceballos, EE Godoy-Lozano, H Sámano-Sánchez, ... MAbs 7 (3), 516-524, 2015 | 29 | 2015 |
Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity L Van der Weyden, AG Rust, RE McIntyre, CD Robles-Espinoza, ... Oncogene 32 (3), 397-402, 2013 | 25 | 2013 |
Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis M Del Castillo Velasco‐Herrera, L van der Weyden, J Nsengimana, ... Molecular oncology 12 (2), 239-255, 2018 | 23 | 2018 |
Sanger Mouse Genetics P RE McIntyre, P Lakshminarasimhan Chavali, O Ismail, DM Carragher, ... Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH …, 2012 | 11 | 2012 |
FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks A Mazouzi, SC Moser, F Abascal, B van den Broek, ... Science Advances 9 (22), eadf4409, 2023 | 6 | 2023 |