Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice K Aihara, H Azuma, M Akaike, Y Ikeda, M Yamashita, T Sudo, H Hayashi, ... Journal of Biological Chemistry 279 (34), 35798-35802, 2004 | 314 | 2004 |
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction Y Ikeda, K Sato, DR Pimentel, F Sam, RJ Shaw, JRB Dyck, K Walsh Journal of Biological Chemistry 284 (51), 35839-35849, 2009 | 181 | 2009 |
Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis Y Ikeda, K Aihara, T Sato, M Akaike, M Yoshizumi, Y Suzaki, Y Izawa, ... Journal of Biological Chemistry 280 (33), 29661-29666, 2005 | 172 | 2005 |
Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes Y Ikeda, S Tajima, Y Izawa-Ishizawa, Y Kihira, K Ishizawa, S Tomita, ... PloS one 7 (7), e40465, 2012 | 144 | 2012 |
Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease R Summer, CA Fiack, Y Ikeda, K Sato, D Dwyer, N Ouchi, A Fine, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (3 …, 2009 | 137 | 2009 |
Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes KKAy mice S Tajima, Y Ikeda, K Sawada, N Yamano, Y Horinouchi, Y Kihira, ... American Journal of Physiology-Endocrinology and Metabolism 302 (1), E77-E86, 2012 | 120 | 2012 |
Pharmacology in health food: metabolism of quercetin in vivo and its protective effect against arteriosclerosis K Ishizawa, M Yoshizumi, Y Kawai, J Terao, Y Kihira, Y Ikeda, S Tomita, ... Journal of pharmacological sciences 115 (4), 466-470, 2011 | 119 | 2011 |
Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II–induced cardiovascular remodeling and renal insufficiency S Yagi, K Aihara, Y Ikeda, Y Sumitomo, S Yoshida, T Ise, T Iwase, ... Circulation research 102 (1), 68-76, 2008 | 115 | 2008 |
Transforming Growth Factor‐β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome K Aihara, Y Ikeda, S Yagi, M Akaike, T Matsumoto Cardiology research and practice 2011 (1), 175381, 2011 | 102 | 2011 |
Heparin cofactor II is a novel protective factor against carotid atherosclerosis in elderly individuals K Aihara, H Azuma, N Takamori, Y Kanagawa, M Akaike, M Fujimura, ... Circulation 109 (22), 2761-2765, 2004 | 93 | 2004 |
Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction Y Ikeda, I Ozono, S Tajima, M Imao, Y Horinouchi, Y Izawa-Ishizawa, ... PloS one 9 (2), e89355, 2014 | 88 | 2014 |
Endothelial nitric oxide synthase–independent protective action of statin against angiotensin II–induced atrial remodeling via reduced oxidant injury S Yagi, M Akaike, K Aihara, K Ishikawa, T Iwase, Y Ikeda, T Soeki, ... Hypertension 55 (4), 918-923, 2010 | 79 | 2010 |
Deferoxamine promotes angiogenesis via the activation of vascular endothelial cell function Y Ikeda, S Tajima, S Yoshida, N Yamano, Y Kihira, K Ishizawa, K Aihara, ... Atherosclerosis 215 (2), 339-347, 2011 | 77 | 2011 |
Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like peptide-1 secretion and reduces adipose tissue inflammation Y Kihira, M Miyake, M Hirata, Y Hoshina, K Kato, H Shirakawa, H Sakaue, ... PLoS One 9 (4), e93856, 2014 | 76 | 2014 |
Androgen-androgen receptor system protects against angiotensin II-induced vascular remodeling Y Ikeda, K Aihara, S Yoshida, T Sato, S Yagi, T Iwase, Y Sumitomo, T Ise, ... Endocrinology 150 (6), 2857-2864, 2009 | 74 | 2009 |
Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice Y Ikeda, K Aihara, M Akaike, T Sato, K Ishikawa, T Ise, S Yagi, T Iwase, ... Molecular Endocrinology 24 (7), 1338-1348, 2010 | 72 | 2010 |
Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes Y Ikeda, K Ohashi, R Shibata, DR Pimentel, S Kihara, N Ouchi, K Walsh FEBS letters 582 (7), 1147-1150, 2008 | 68 | 2008 |
Smooth muscle cell-specific Hif-1α deficiency suppresses angiotensin II-induced vascular remodelling in mice M Imanishi, S Tomita, K Ishizawa, Y Kihira, M Ueno, Y Izawa-Ishizawa, ... Cardiovascular research 102 (3), 460-468, 2014 | 64 | 2014 |
Dietary iron restriction inhibits progression of diabetic nephropathy in db/db mice Y Ikeda, H Enomoto, S Tajima, Y Izawa-Ishizawa, Y Kihira, K Ishizawa, ... American Journal of Physiology-Renal Physiology 304 (7), F1028-F1036, 2013 | 60 | 2013 |
Dehydroepiandrosterone sulfate is inversely associated with sex-dependent diverse carotid atherosclerosis regardless of endothelial function S Yoshida, K Aihara, H Azuma, R Uemoto, Y Sumitomo-Ueda, S Yagi, ... Atherosclerosis 212 (1), 310-315, 2010 | 59 | 2010 |