| Lactate activation of α-cell KATP channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca2+ entry KE Zaborska, PK Dadi, MT Dickerson, AY Nakhe, AS Thorson, ... Molecular Metabolism 42, 101056, 2020 | 25 | 2020 |
| Tetraspanin‐7 regulation of L‐type voltage‐dependent calcium channels controls pancreatic β‐cell insulin secretion MT Dickerson, PK Dadi, RB Butterworth, AY Nakhe, SM Graff, ... The Journal of physiology 598 (21), 4887-4905, 2020 | 22 | 2020 |
| A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young SM Graff, SR Johnson, PJ Leo, PK Dadi, MT Dickerson, AY Nakhe, ... JCI insight 6 (13), 2021 | 21 | 2021 |
| Gi/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na+/K+ ATPase activation MT Dickerson, PK Dadi, KE Zaborska, AY Nakhe, CM Schaub, JR Dobson, ... Nature Communications 13 (1), 6461, 2022 | 13 | 2022 |
| Liraglutide increases islet Ca2+ oscillation frequency and insulin secretion by activating hyperpolarization‐activated cyclic nucleotide‐gated channels KE Zaborska, KL Jordan, AS Thorson, PK Dadi, CM Schaub, AY Nakhe, ... Diabetes, Obesity and Metabolism 24 (9), 1741-1752, 2022 | 9 | 2022 |
| Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells M Rahim, AY Nakhe, DR Banerjee, EM Overway, KJ Bosma, JC Rosch, ... Journal of Biological Chemistry 298 (4), 2022 | 9 | 2022 |
| TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced β-cell proliferation MK Altman, CM Schaub, PK Dadi, MT Dickerson, KE Zaborska, AY Nakhe, ... Development 148 (16), dev194928, 2021 | 6 | 2021 |
| TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet SM Graff, AY Nakhe, PK Dadi, MT Dickerson, JR Dobson, KE Zaborska, ... Cell reports 43 (1), 2024 | 1 | 2024 |
| 2075-P: Testing the First Selective Talk-1 Inhibitors for Their Ability to Improve ß-Cell Function in Diabetes AY Nakhe, P Dadi, D Westover, J DENTON, D JACOBSON Diabetes 69 (Supplement_1), 2020 | 1 | 2020 |
| 1741-P: The Type 2 Diabetes–Associated K+ Channel TALK-2 Is Localized to the Endoplasmic Reticulum and Modulates Beta Cell Ca2+ Handling and Insulin Secretion J DOBSON, P DADI, AY NAKHE, D JACOBSON Diabetes 73 (Supplement_1), 2024 | | 2024 |
| The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in … AY Nakhe, PK Dadi, J Kim, MT Dickerson, S Behera, JR Dobson, ... Elife 12, RP89967, 2024 | | 2024 |
| Channeling glycemia: The role of islet TALK-1 gain-and loss-of-function channels in Ca2+ handling, metabolism, hormone secretion, and insulin sensitivity AY Nakhe | | 2023 |
| IP3Rs puff along: A SNAPpy dance with IP3 and Ca2+ AY Nakhe, DA Jacobson Journal of Biological Chemistry 299 (3), 2023 | | 2023 |
| Illuminating the mechanism for G (i/o) protein-coupled receptor inhibition of beta cell Ca2+ influx and insulin secretion MT Dickerson, PK Dadi, KE Zaborska, AY Nakhe, CM Schaub, JR Dobson, ... DIABETOLOGIA 65 (SUPPL 1), S194-S195, 2022 | | 2022 |
| Investigating the role of a novel MODY-associated gain-of-function mutation in TALK-1 in islet dysfunction and glucose intolerance AY Nakhe, J Kim, PK Dadi, KE Zaborska, DA Jacobson DIABETOLOGIA 65 (SUPPL 1), S213-S213, 2022 | | 2022 |
| Na plus/K plus ATPase Activation Is a Conserved Mechanism for Gi/o Protein-Coupled Receptor Control of Pancreatic beta-Cell Electrical Excitability and Insulin Secretion M Dickerson, P Dadi, KE Zaborska, AY Nakhe, C Schaub, J Dobson, ... DIABETES 71, 2022 | | 2022 |
| 319-OR: Na+/K+ ATPase Activation Is a Conserved Mechanism for Gi/o Protein-Coupled Receptor Control of Pancreatic ß-Cell Electrical Excitability and Insulin Secretion M DICKERSON, P DADI, KE ZABORSKA, AY NAKHE, C SCHAUB, ... Diabetes 71 (Supplement_1), 2022 | | 2022 |
| 257-LB: A Novel MODY-Associated Gain-of-Function Mutation in TALK-1 Leads to Islet Dysfunction and Glucose Intolerance AY Nakhe, P Dadi, KE Zaborska, D Jacobson Diabetes 71 (Supplement_1), 2022 | | 2022 |
| 225-LB: Targeting ß-Cell Endoplasmic Reticulum (ER) TALK-1 Channels to Restore Ca2+ Homeostasis and Reduce ER Stress in Diabetes AY Nakhe, P Dadi, D Westover, J DENTON, D JACOBSON Diabetes 70 (Supplement_1), 2021 | | 2021 |
| A novel mutation in KCNK16 causing a gain-of-function in the TALK-1 potassium channel: a new cause of maturity onset diabetes of the young SM Graff, SR Johnson, PJ Leo, PK Dadi, AY Nakhe, AM McInerney-Leo, ... bioRxiv, 2020.02. 04.929430, 2020 | | 2020 |
