| Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling Y Zhou, CO Wong, K Cho, D Van Der Hoeven, H Liang, DP Thakur, J Luo, ... Science 349 (6250), 873-876, 2015 | 298 | 2015 |
| The role of TRPMLs in endolysosomal trafficking and function K Venkatachalam, CO Wong, MX Zhu Cell calcium 58 (1), 48-56, 2015 | 215 | 2015 |
| Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells X Ma, KT Cheng, CO Wong, RG O’Neil, L Birnbaumer, IS Ambudkar, ... Cell calcium 50 (6), 502-509, 2011 | 146 | 2011 |
| Drosophila TRPML is required for TORC1 activation CO Wong, R Li, C Montell, K Venkatachalam Current Biology 22 (17), 1616-1621, 2012 | 132 | 2012 |
| Functional Role of Vanilloid Transient Receptor Potential 4-Canonical Transient Receptor Potential 1 Complex in Flow-Induced Ca2+ Influx X Ma, S Qiu, J Luo, Y Ma, CY Ngai, B Shen, C Wong, Y Huang, X Yao Arteriosclerosis, thrombosis, and vascular biology 30 (4), 851-858, 2010 | 128 | 2010 |
| The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function CM Chan, H Tsoi, WM Chan, S Zhai, CO Wong, X Yao, WY Chan, ... The International Journal of Biochemistry & Cell Biology 41 (11), 2232-2239, 2009 | 107 | 2009 |
| Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila F Martelli, Z Zhongyuan, J Wang, CO Wong, NE Karagas, U Roessner, ... Proceedings of the National Academy of Sciences 117 (41), 25840-25850, 2020 | 97 | 2020 |
| Lysosomal degradation is required for sustained phagocytosis of bacteria by macrophages CO Wong, S Gregory, H Hu, Y Chao, VE Sepúlveda, Y He, D Li-Kroeger, ... Cell host & microbe 21 (6), 719-730. e6, 2017 | 94 | 2017 |
| HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition J Jung, KJ Cho, AK Naji, KN Clemons, CO Wong, M Villanueva, ... EMBO reports 20 (4), e46685, 2019 | 85 | 2019 |
| Drosophila TRPML forms PI (3, 5) P2-activated cation channels in both endolysosomes and plasma membrane X Feng, Y Huang, Y Lu, J Xiong, CO Wong, P Yang, J Xia, D Chen, G Du, ... Journal of Biological Chemistry 289 (7), 4262-4272, 2014 | 76 | 2014 |
| TRPC5 channels participate in pressure-sensing in aortic baroreceptors OC Lau, B Shen, CO Wong, YW Tjong, CY Lo, HC Wang, Y Huang, ... Nature communications 7 (1), 11947, 2016 | 75 | 2016 |
| A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission CO Wong, K Chen, YQ Lin, Y Chao, L Duraine, Z Lu, WH Yoon, ... Neuron 84 (4), 764-777, 2014 | 73 | 2014 |
| cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway B Shen, HY Kwan, X Ma, CO Wong, J Du, Y Huang, X Yao Journal of Biological Chemistry 286 (22), 19439-19445, 2011 | 66 | 2011 |
| Plasma membrane mechanical stress activates TRPC5 channels B Shen, CO Wong, OC Lau, T Woo, S Bai, Y Huang, X Yao PLoS One 10 (4), e0122227, 2015 | 57 | 2015 |
| Feast or famine: role of TRPML in preventing cellular amino acid starvation K Venkatachalam, CO Wong, C Montell Autophagy 9 (1), 98-100, 2013 | 43 | 2013 |
| Genistein potentiates activity of the cation channel TRPC5 independently of tyrosine kinases CO Wong, Y Huang, X Yao British journal of pharmacology 159 (7), 1486-1496, 2010 | 41 | 2010 |
| TRP channels in vascular endothelial cells CO Wong, X Yao Transient Receptor Potential Channels, 759-780, 2011 | 38 | 2011 |
| Epinephrine-induced Ca2+ influx in vascular endothelial cells is mediated by CNGA2 channels B Shen, KT Cheng, YK Leung, YC Kwok, HY Kwan, CO Wong, ZY Chen, ... Journal of molecular and cellular cardiology 45 (3), 437-445, 2008 | 38 | 2008 |
| Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB KH Chan, T Li, CO Wong, KB Wong PLoS One 7 (1), e30547, 2012 | 37 | 2012 |
| Diminished MTORC1-dependent JNK activation underlies the neurodevelopmental defects associated with lysosomal dysfunction CO Wong, M Palmieri, J Li, D Akhmedov, Y Chao, GT Broadhead, MX Zhu, ... Cell reports 12 (12), 2009-2020, 2015 | 35 | 2015 |
