Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications J Zielonka, J Joseph, A Sikora, M Hardy, O Ouari, J Vasquez-Vivar, ... Chemical reviews 117 (15), 10043-10120, 2017 | 1246 | 2017 |
Hydroethidine-and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth J Zielonka, B Kalyanaraman Free Radical Biology and Medicine 48 (8), 983-1001, 2010 | 584 | 2010 |
Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine J Zielonka, J Vasquez-Vivar, B Kalyanaraman Nature protocols 3 (1), 8-21, 2008 | 457 | 2008 |
Direct oxidation of boronates by peroxynitrite: mechanism and implications in fluorescence imaging of peroxynitrite A Sikora, J Zielonka, M Lopez, J Joseph, B Kalyanaraman Free Radical Biology and Medicine 47 (10), 1401-1407, 2009 | 358 | 2009 |
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 316 | 2017 |
Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death G Cheng, J Zielonka, BP Dranka, D McAllister, AC Mackinnon Jr, ... Cancer research 72 (10), 2634-2644, 2012 | 284 | 2012 |
Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides J Zielonka, A Sikora, M Hardy, J Joseph, BP Dranka, B Kalyanaraman Chemical research in toxicology 25 (9), 1793-1799, 2012 | 250 | 2012 |
Peroxynitrite Is the Major Species Formed from Different Flux Ratios of Co-generated Nitric Oxide and Superoxide: DIRECT REACTION WITH BORONATE-BASED FLUORESCENT PROBE*♦ J Zielonka, A Sikora, J Joseph, B Kalyanaraman Journal of Biological Chemistry 285 (19), 14210-14216, 2010 | 246 | 2010 |
Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy P Mukhopadhyay, B Horváth, Z Zsengellér, J Zielonka, G Tanchian, ... Free Radical Biology and Medicine 52 (2), 497-506, 2012 | 232 | 2012 |
Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q K Chandran, D Aggarwal, RQ Migrino, J Joseph, D McAllister, ... Biophysical Journal 96 (4), 1388-1398, 2009 | 214 | 2009 |
Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies B Kalyanaraman, G Cheng, M Hardy, O Ouari, B Bennett, J Zielonka Redox biology 15, 347-362, 2018 | 210 | 2018 |
A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic … B Kalyanaraman, G Cheng, M Hardy, O Ouari, M Lopez, J Joseph, ... Redox biology 14, 316-327, 2018 | 210 | 2018 |
Global profiling of reactive oxygen and nitrogen species in biological systems J Zielonka, M Zielonka, A Sikora, J Adamus, J Joseph, M Hardy, O Ouari, ... Journal of Biological Chemistry 287 (5), 2984-2995, 2012 | 197 | 2012 |
Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells G Cheng, J Zielonka, O Ouari, M Lopez, D McAllister, K Boyle, CS Barrios, ... Cancer research 76 (13), 3904-3915, 2016 | 193 | 2016 |
HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements J Zielonka, M Hardy, B Kalyanaraman Free Radical Biology and Medicine 46 (3), 329-338, 2009 | 173 | 2009 |
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis G Cheng, Q Zhang, J Pan, Y Lee, O Ouari, M Hardy, M Zielonka, ... Nature communications 10 (1), 2205, 2019 | 170 | 2019 |
Transient Species in the Stepwise Interconversion of NADH and NAD+ J Gebicki, A Marcinek, J Zielonka Accounts of chemical research 37 (6), 379-386, 2004 | 163 | 2004 |
The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone VA Rao, SR Klein, SJ Bonar, J Zielonka, N Mizuno, JS Dickey, PW Keller, ... Journal of Biological Chemistry 285 (45), 34447-34459, 2010 | 154 | 2010 |
Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death G Cheng, J Zielonka, DM McAllister, AC Mackinnon, J Joseph, ... BMC cancer 13, 1-14, 2013 | 147 | 2013 |
Mechanism of oxidative conversion of Amplex® Red to resorufin: pulse radiolysis and enzymatic studies D Dębski, R Smulik, J Zielonka, B Michałowski, M Jakubowska, ... Free Radical Biology and Medicine 95, 323-332, 2016 | 144 | 2016 |