Production of complex viral glycoproteins in plants as vaccine immunogens E Margolin, R Chapman, AL Williamson, EP Rybicki, AE Meyers Plant biotechnology journal 16 (9), 1531-1545, 2018 | 80 | 2018 |
Co‐expression of human calreticulin significantly improves the production of HIV gp140 and other viral glycoproteins in plants E Margolin, YJ Oh, M Verbeek, J Naude, D Ponndorf, YA Meshcheriakova, ... Plant Biotechnology Journal 18 (10), 2109-2117, 2020 | 59 | 2020 |
Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa E Margolin, WA Burgers, ED Sturrock, M Mendelson, R Chapman, ... Nature Reviews Microbiology 18 (12), 690-704, 2020 | 58 | 2020 |
Recombinant Mycobacterium bovis BCG as an HIV vaccine vector R Chapman, G Chege, E Shephard, H Stutz, AL Williamson Current HIV research 8 (4), 282-298, 2010 | 57 | 2010 |
Engineering the plant secretory pathway for the production of next-generation pharmaceuticals EA Margolin, R Strasser, R Chapman, AL Williamson, EP Rybicki, ... Trends in Biotechnology 38 (9), 1034-1044, 2020 | 51 | 2020 |
Production and immunogenicity of soluble plant-produced HIV-1 subtype C envelope gp140 immunogens E Margolin, R Chapman, AE Meyers, MT Van Diepen, P Ximba, ... Frontiers in plant science 10, 1378, 2019 | 40 | 2019 |
Improved DNA vaccine delivery with needle-free injection systems C Ledesma-Feliciano, R Chapman, JW Hooper, K Elma, D Zehrung, ... Vaccines 11 (2), 280, 2023 | 37 | 2023 |
Prime-boost immunizations with DNA, modified vaccinia virus Ankara, and protein-based vaccines elicit robust HIV-1 tier 2 neutralizing antibodies against the CAP256 … MT van Diepen, R Chapman, N Douglass, S Galant, PL Moore, ... Journal of virology 93 (8), 10.1128/jvi. 02155-18, 2019 | 33 | 2019 |
Heterologous prime-boost vaccination with DNA and MVA vaccines, expressing HIV-1 subtype C mosaic Gag virus-like particles, is highly immunogenic in mice R Chapman, TI Jongwe, N Douglass, G Chege, AL Williamson PloS one 12 (3), e0173352, 2017 | 32 | 2017 |
A roadmap for the molecular farming of viral glycoprotein vaccines: engineering glycosylation and glycosylation-directed folding E Margolin, M Crispin, A Meyers, R Chapman, EP Rybicki Frontiers in Plant Science 11, 609207, 2020 | 26 | 2020 |
Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8+ T Cells R Chapman, E Shephard, H Stutz, N Douglass, V Sambandamurthy, ... PLoS One 7 (3), e32769, 2012 | 26 | 2012 |
Priming with recombinant auxotrophic BCG expressing HIV-1 Gag, RT and Gp120 and boosting with recombinant MVA induces a robust T cell response in mice R Chapman, H Stutz, W Jacobs Jr, E Shephard, AL Williamson PLoS One 8 (8), e71601, 2013 | 24 | 2013 |
The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256 MT van Diepen, R Chapman, PL Moore, E Margolin, T Hermanus, ... PLoS One 13 (12), e0208310, 2018 | 20 | 2018 |
Site-Specific Glycosylation of Recombinant Viral Glycoproteins Produced in Nicotiana benthamiana E Margolin, JD Allen, M Verbeek, M Van Diepen, P Ximba, R Chapman, ... Frontiers in Plant Science 12, 709344, 2021 | 15 | 2021 |
Immunogenicity of HIV-1 vaccines expressing chimeric envelope glycoproteins on the surface of Pr55 Gag virus-like particles R Chapman, M van Diepen, S Galant, E Kruse, E Margolin, P Ximba, ... Vaccines 8 (1), 54, 2020 | 15 | 2020 |
Use of a novel enhanced DNA vaccine vector for preclinical virus vaccine investigation R Chapman, EP Rybicki Vaccines 7 (2), 50, 2019 | 15 | 2019 |
Advancements in the growth and construction of recombinant lumpy skin disease virus (LSDV) for use as a vaccine vector M van Diepen, R Chapman, N Douglass, L Whittle, N Chineka, S Galant, ... Vaccines 9 (10), 1131, 2021 | 14 | 2021 |
HIV-1 subtype C mosaic gag expressed by BCG and MVA elicits persistent effector T cell responses in a prime-boost regimen in mice TI Jongwe, R Chapman, N Douglass, S Chetty, G Chege, AL Williamson PloS one 11 (7), e0159141, 2016 | 14 | 2016 |
The pyruvate dehydrogenase complex of the chemolithoautotrophic bacterium Thiobacillus ferrooxidans has an unusual E2-E3 subunit fusion R Powles, D Rawlings Microbiology 143 (7), 2189-2195, 1997 | 14 | 1997 |
The gene for γ-glutamylcysteine synthetase from Thiobacillus ferrooxidans has low homology to its Escherichia coli equivalent and is linked to the gene for citrate … R Powles, S Deane, D Rawlings Microbiology 142 (9), 2543-2548, 1996 | 14 | 1996 |