Quantitative determination of endogenous compounds in biological samples using chromatographic techniques NC van de Merbel TrAC Trends in Analytical Chemistry 27 (10), 924-933, 2008 | 257 | 2008 |
Internal standards in the quantitative determination of protein biopharmaceuticals using liquid chromatography coupled to mass spectrometry KJ Bronsema, R Bischoff, NC van de Merbel Journal of Chromatography B 893, 1-14, 2012 | 174 | 2012 |
Membrane-based sample preparation coupled on-line to chromatography or electrophoresis NC Van de Merbel Journal of Chromatography A 856 (1-2), 55-82, 1999 | 140 | 1999 |
The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium R de Vries, M Barfield, N van de Merbel, B Schmid, C Siethoff, J Ortiz, ... Bioanalysis 5 (17), 2147-2160, 2013 | 129 | 2013 |
Membrane-based sample preparation for chromatography NC Van de Merbel, JJ Hageman, UAT Brinkman Journal of Chromatography A 634 (1), 1-29, 1993 | 128 | 1993 |
Validated method for the determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography–tandem mass spectrometry BMM Remmerie, LLA Sips, R De Vries, J De Jong, AM Schothuis, ... Journal of Chromatography B 783 (2), 461-472, 2003 | 111 | 2003 |
High-sensitivity LC-MS/MS quantification of peptides and proteins in complex biological samples: the impact of enzymatic digestion and internal standard selection on method … KJ Bronsema, R Bischoff, NC van de Merbel Analytical chemistry 85 (20), 9528-9535, 2013 | 106 | 2013 |
LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma P Bults, R Bischoff, H Bakker, JA Gietema, NC van de Merbel Analytical chemistry 88 (3), 1871-1877, 2016 | 104 | 2016 |
Validated LC–MS/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine M De Meulder, BMM Remmerie, R de Vries, LLA Sips, S Boom, ... Journal of Chromatography B 870 (1), 8-16, 2008 | 91 | 2008 |
Stability: recommendation for best practices and harmonization from the Global Bioanalysis Consortium Harmonization Team N van de Merbel, N Savoie, M Yadav, Y Ohtsu, J White, MF Riccio, ... The AAPS Journal 16, 392-399, 2014 | 77 | 2014 |
Quantitative determination of free and total dopamine in human plasma by LC–MS/MS: the importance of sample preparation NC van de Merbel, G Hendriks, R Imbos, J Tuunainen, J Rouru, ... Bioanalysis 3 (17), 1949-1961, 2011 | 76 | 2011 |
In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium Z Cobb, R de Vries, N Spooner, S Williams, L Staelens, M Doig, ... Bioanalysis 5 (17), 2161-2169, 2013 | 75 | 2013 |
Protein Quantification by LC–MS: A Decade of Progress Through the Pages of Bioanalysis NC van de Merbel Bioanalysis 11 (7), 629-644, 2019 | 74 | 2019 |
Sampling and analytical strategies in on-line bioprocess monitoring and control NC Van de Merbel, H Lingeman, UAT Brinkman Journal of Chromatography A 725 (1), 13-27, 1996 | 62 | 1996 |
Determination of aflatoxin M1 using a dialysis-based immunoaffinity sample pretreatment system coupled online to liquid chromatography: Reusable immunoaffinity columns A Farjam, NC Van de Merbel, AA Nieman, H Lingeman, UAT Brinkman Journal of Chromatography A 589 (1-2), 141-149, 1992 | 58 | 1992 |
A validated liquid chromatography–tandem mass spectrometry method for the quantitative determination of 4β-hydroxycholesterol in human plasma NC van de Merbel, KJ Bronsema, MWJ van Hout, R Nilsson, H Sillén Journal of pharmaceutical and biomedical analysis 55 (5), 1089-1095, 2011 | 57 | 2011 |
Dialysis as an on-line sample-pretreatment technique for column liquid chromatography: influence of experimental variables upon the determination of benzodiazepines in human plasma NC Van de Merbel, JM Teule, H Lingeman, UAT Brinkman Journal of pharmaceutical and biomedical analysis 10 (2-3), 225-233, 1992 | 57 | 1992 |
Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of liquid chromatography coupled to tandem mass spectrometry and ligand binding … P Bults, NC van de Merbel, R Bischoff Expert review of proteomics 12 (4), 355-374, 2015 | 46 | 2015 |
Quantification of free and total desmosine and isodesmosine in human urine by liquid chromatography tandem mass spectrometry: a comparison of the surrogate-analyte and the … S Ongay, G Hendriks, J Hermans, M van den Berge, NHT ten Hacken, ... Journal of Chromatography A 1326, 13-19, 2014 | 45 | 2014 |
Automated column liquid chromatographic determination of amoxicillin and cefadroxil in bovine serum and muscle tissue using on-line dialysis for sample preparation N Snippe, NC Van de Merbel, FPM Ruiter, OM Steijger, H Lingeman, ... Journal of Chromatography B: Biomedical Sciences and Applications 662 (1), 61-70, 1994 | 42 | 1994 |