Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation TN Nguyen, BS Padman, J Usher, V Oorschot, G Ramm, M Lazarou Journal of Cell Biology 215 (6), 857-874, 2016 | 623 | 2016 |
Deciphering the molecular signals of PINK1/Parkin mitophagy TN Nguyen, BS Padman, M Lazarou Trends in cell biology 26 (10), 733-744, 2016 | 598 | 2016 |
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy BS Padman, TN Nguyen, L Uoselis, M Skulsuppaisarn, LK Nguyen, ... Nature communications 10 (1), 408, 2019 | 204 | 2019 |
Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function SB Ma, TN Nguyen, I Tan, R Ninnis, S Iyer, DA Stroud, M Menard, ... Cell Death & Differentiation 21 (12), 1925-1935, 2014 | 141 | 2014 |
Gene knockout using transcription activator-like effector nucleases (TALENs) reveals that human NDUFA9 protein is essential for stabilizing the junction between membrane and … DA Stroud, LE Formosa, XW Wijeyeratne, TN Nguyen, MT Ryan Journal of Biological Chemistry 288 (3), 1685-1690, 2013 | 103 | 2013 |
The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation J Lauterwasser, F Todt, RM Zerbes, TN Nguyen, W Craigen, M Lazarou, ... Scientific reports 6 (1), 32994, 2016 | 90 | 2016 |
ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system TN Nguyen, BS Padman, S Zellner, G Khuu, L Uoselis, WK Lam, ... Molecular cell 81 (9), 2013-2030. e9, 2021 | 69 | 2021 |
A human apolipoprotein L with detergent-like activity kills intracellular pathogens RG Gaudet, S Zhu, A Halder, BH Kim, CJ Bradfield, S Huang, D Xu, ... Science 373 (6552), eabf8113, 2021 | 67 | 2021 |
Mitochondrial degradation: Mitophagy and beyond L Uoselis, TN Nguyen, M Lazarou Molecular cell 83 (19), 3404-3420, 2023 | 56 | 2023 |
Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs BS Padman, TN Nguyen, M Lazarou Autophagy 13 (4), 772-774, 2017 | 42 | 2017 |
Unconventional initiation of PINK1/Parkin mitophagy by Optineurin TN Nguyen, J Sawa-Makarska, G Khuu, WK Lam, E Adriaenssens, ... Molecular cell 83 (10), 1693-1709. e9, 2023 | 41 | 2023 |
Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation X Ren, TN Nguyen, WK Lam, CZ Buffalo, M Lazarou, AL Yokom, ... Science advances 9 (7), eadg2997, 2023 | 27 | 2023 |
Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5 MLCKY Sung-Eun Nam, Yiu Wing Sunny Cheung, Thanh Ngoc Nguyen, Michael Gong ... Communications Biology, 2021 | 16 | 2021 |
A unifying model for the role of the ATG8 system in autophagy TN Nguyen, M Lazarou Journal of Cell Science 135 (11), jcs258997, 2022 | 15 | 2022 |
ATG8ylation of proteins: A way to cope with cell stress? JM Carosi, TN Nguyen, M Lazarou, S Kumar, TJ Sargeant Journal of Cell Biology 220 (11), 2021 | 15 | 2021 |
Plant mitophagy: beware of Friendly or you might get eaten TN Nguyen, M Lazarou Current Biology 31 (9), R457-R458, 2021 | 7 | 2021 |
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex JHH Minghao Chen, Xuefeng Ren, Thanh N. Nguyen, Grace Khuu, Annan S. I. Cook ... biorxiv, https://www.biorxiv.org/content/10.1101/, 2023 | 6* | 2023 |
ATG4s: above and beyond the Atg8-family protein lipidation system TN Nguyen, BS Padman, M Lazarou Autophagy 17 (9), 2648-2650, 2021 | 6 | 2021 |
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy TL Saunders, SP Windley, G Gervinskas, KR Balka, C Rowe, R Lane, ... Cell Death & Differentiation 31 (3), 335-347, 2024 | 5 | 2024 |
A human apolipoprotein L with detergent-like activity kills intracellular pathogens. Science 373, eabf8113 RG Gaudet, S Zhu, A Halder, BH Kim, CJ Bradfield, S Huang, D Xu, ... | 5 | 2021 |