Computational strategies for dissecting the high-dimensional complexity of adaptive immune repertoires E Miho, A Yermanos, CR Weber, CT Berger, ST Reddy, V Greiff Frontiers in immunology 9, 224, 2018 | 191 | 2018 |
A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer L D’Amico, U Menzel, M Prummer, P Müller, M Buchi, A Kashyap, ... Journal for immunotherapy of cancer 7, 1-15, 2019 | 95 | 2019 |
Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain JM Taft, CR Weber, B Gao, RA Ehling, J Han, L Frei, SW Metcalfe, ... Cell 185 (21), 4008-4022. e14, 2022 | 68 | 2022 |
immuneSIM: tunable multi-feature simulation of B-and T-cell receptor repertoires for immunoinformatics benchmarking CR Weber, R Akbar, A Yermanos, M Pavlović, I Snapkov, GK Sandve, ... Bioinformatics 36 (11), 3594-3596, 2020 | 67 | 2020 |
Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory M Borsa, I Barnstorf, NS Baumann, K Pallmer, A Yermanos, F Gräbnitz, ... Science immunology 4 (34), eaav1730, 2019 | 63 | 2019 |
Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim) A Yermanos, V Greiff, NJ Krautler, U Menzel, A Dounas, E Miho, ... Bioinformatics 33 (24), 3938-3946, 2017 | 50 | 2017 |
Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons D Frieser, A Pignata, L Khajavi, D Shlesinger, C Gonzalez-Fierro, ... Science translational medicine 14 (640), eabl6157, 2022 | 44 | 2022 |
A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients F Bieberich, R Vazquez-Lombardi, A Yermanos, RA Ehling, DM Mason, ... Frontiers in immunology 12, 701085, 2021 | 41 | 2021 |
Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection SPM Welten, A Yermanos, NS Baumann, F Wagen, N Oetiker, I Sandu, ... Nature communications 11 (1), 2295, 2020 | 39 | 2020 |
Quantitative and qualitative analysis of humoral immunity reveals continued and personalized evolution in chronic viral infection NJ Kräutler, A Yermanos, A Pedrioli, SPM Welten, D Lorgé, U Greczmiel, ... Cell reports 30 (4), 997-1012. e6, 2020 | 36 | 2020 |
Discovery and validation of human genomic safe harbor sites for gene and cell therapies E Aznauryan, A Yermanos, E Kinzina, A Devaux, E Kapetanovic, ... Cell Reports Methods 2 (1), 2022 | 33 | 2022 |
Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes A Yermanos, A Agrafiotis, R Kuhn, D Robbiani, J Yates, C Papadopoulou, ... NAR genomics and bioinformatics 3 (2), lqab023, 2021 | 31 | 2021 |
Modulation of BK channel by MicroRNA-9 in neurons after exposure to HIV and methamphetamine ET Tatro, S Hefler, S Shumaker-Armstrong, B Soontornniyomkij, M Yang, ... Journal of neuroimmune pharmacology 8, 1210-1223, 2013 | 30 | 2013 |
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS I Vincenti, N Page, K Steinbach, A Yermanos, S Lemeille, N Nunez, ... Science translational medicine 14 (640), eabl6058, 2022 | 29 | 2022 |
Tracing antibody repertoire evolution by systems phylogeny AD Yermanos, AK Dounas, T Stadler, A Oxenius, ST Reddy Frontiers in immunology 9, 2149, 2018 | 28 | 2018 |
Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner I Barnstorf, M Borsa, N Baumann, K Pallmer, A Yermanos, N Joller, ... Journal of Experimental Medicine 216 (3), 571-586, 2019 | 25 | 2019 |
Applications of machine and deep learning in adaptive immunity M Pertseva, B Gao, D Neumeier, A Yermanos, ST Reddy Annual Review of Chemical and Biomolecular Engineering 12 (1), 39-62, 2021 | 23 | 2021 |
Rapid expansion of Treg cells protects from collateral colitis following a viral trigger M Schorer, K Lambert, N Rakebrandt, F Rost, KC Kao, A Yermanos, ... Nature communications 11 (1), 1522, 2020 | 22 | 2020 |
Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells D Neumeier, A Yermanos, A Agrafiotis, L Csepregi, T Chowdhury, ... Proceedings of the National Academy of Sciences 119 (18), e2113766119, 2022 | 20 | 2022 |
TLR7 signaling shapes and maintains antibody diversity upon virus-like particle immunization X Chang, P Krenger, CC Krueger, L Zha, J Han, A Yermanos, S Roongta, ... Frontiers in immunology 12, 827256, 2022 | 19 | 2022 |