Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, J Kloepper, ... Proceedings of the National Academy of Sciences 113 (16), 4470-4475, 2016 | 306 | 2016 |
IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells DT Fisher, Q Chen, JJ Skitzki, JB Muhitch, L Zhou, MM Appenheimer, ... The Journal of clinical investigation 121 (10), 3846-3859, 2011 | 260 | 2011 |
Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 J Incio, JA Ligibel, DT McManus, P Suboj, K Jung, K Kawaguchi, M Pinter, ... Science translational medicine 10 (432), eaag0945, 2018 | 189 | 2018 |
Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells R Samuel, L Daheron, S Liao, T Vardam, WS Kamoun, A Batista, ... Proceedings of the National Academy of Sciences 110 (31), 12774-12779, 2013 | 183 | 2013 |
Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. J Incio, P Suboj, SM Chin, T Vardam-Kaur, H Liu, T Hato, S Babykutty, C I, ... PLoS One 10 (12), 2015 | 145 | 2015 |
PlGF/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity J Incio, J Tam, NN Rahbari, P Suboj, DT McManus, SM Chin, TD Vardam, ... Clinical Cancer Research 22 (12), 2993-3004, 2016 | 142 | 2016 |
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. V Askoxylakis, GB Ferraro, DP Kodak, M Badeaux, RC Shankaraiah, ... J Natl Canc 108 (2), 2015 | 82 | 2015 |
Regulation of a lymphocyte–endothelial–IL-6 trans-signaling axis by fever-range thermal stress: Hot spot of immune surveillance TD Vardam, L Zhou, MM Appenheimer, Q Chen, WC Wang, H Baumann, ... Cytokine 39 (1), 84-96, 2007 | 77 | 2007 |
Phase I and biomarker study of plerixafor and bevacizumab in recurrent high-grade glioma EQ Lee, DG Duda, A Muzikansky, ER Gerstner, JG Kuhn, DA Reardon, ... Clinical Cancer Research 24 (19), 4643-4649, 2018 | 50 | 2018 |
Immune Adjuvant Activity of Pre-Resectional Radiofrequency Ablation Protects against Local and Systemic Recurrence in Aggressive Murine Colorectal Cancer F Ito, AW Ku, MJ Bucsek, JB Muhitch, T Vardam-Kaur, M Kim, DT Fisher, ... PLoS One 10 (11), 2015 | 43 | 2015 |
Fine-tuning immune surveillance by fever-range thermal stress DT Fisher, TD Vardam, JB Muhitch, SS Evans Immunologic research 46, 177-188, 2010 | 23 | 2010 |
In situ thermal ablation augments antitumor efficacy of adoptive T cell therapy F Ito, TD Vardam, MM Appenheimer, KH Eng, SO Gollnick, JB Muhitch, ... International Journal of Hyperthermia 36 (sup1), 22-36, 2019 | 19 | 2019 |
Targeting the tumor microenvironment to enhance pediatric brain cancer treatment A Batista, L Riedemann, T Vardam, RK Jain The Cancer Journal 21 (4), 307-313, 2015 | 18 | 2015 |
The Extracellular ATP Receptor P2RX7 Imprints a Promemory Transcriptional Signature in Effector CD8 + T Cells T Vardam-Kaur, S van Dijk, C Peng, K Wanhainen, J Stephen, ... Journal of Immunology, 2022 | 17 | 2022 |
Metabolic regulation of tissue-resident memory CD8 + T cells T Vardam-Kaur, J Sun, H Borges da Silva Curr Opin Pharmacol 57, 117-124, 2021 | 7 | 2021 |
Langerhans cells orchestrate TFH-dependent humoral immunity T Vardam, N Anandasabapathy Journal of Investigative Dermatology 137 (9), 1826-1828, 2017 | 7 | 2017 |
T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections I Santiago-Carvalho, G Almeida-Santos, BG Macedo, ... Cell reports 42 (11), 2023 | 4 | 2023 |
Abstract LB-346: Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages Z Amoozgar, TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, ... Cancer Research 76 (14_Supplement), LB-346-LB-346, 2016 | 2 | 2016 |
The ATP-exporting channel Pannexin-1 promotes CD8+ T cell effector and memory responses T Vardam-Kaur, A Banuelos, M Gabaldon-Parish, BG Macedo, ... iScience, 2024 | 1 | 2024 |
Multipeptide stimulated PBMCs generate T EM/T CM for adoptive cell therapy in multiple myeloma T Vardam-Kaur, L Pathangey, D McCormick, L Bergsagel, P Cohen, ... Oncotarget 12 (20), 2051-2067, 2021 | 1 | 2021 |