| Molecular mechanisms of action of bisphosphonates: current status AJ Roelofs, K Thompson, S Gordon, MJ Rogers Clinical Cancer Research 12 (20), 6222s-6230s, 2006 | 741 | 2006 |
| Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP AJ Roelofs, M Jauhiainen, H Mönkkönen, MJ Rogers, J Mönkkönen, ... British journal of haematology 144 (2), 245-250, 2009 | 330 | 2009 |
| Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells FP Coxon, K Thompson, AJ Roelofs, FH Ebetino, MJ Rogers Bone 42 (5), 848-860, 2008 | 288 | 2008 |
| Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages A J Roelofs, K Thompson, F H Ebetino, M J Rogers, F P Coxon Current pharmaceutical design 16 (27), 2950-2960, 2010 | 242 | 2010 |
| Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo AJ Roelofs, FP Coxon, FH Ebetino, MW Lundy, ZJ Henneman, ... Journal of Bone and Mineral Research 25 (3), 606-616, 2010 | 192 | 2010 |
| A role for L‐α‐lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells LA Ford, AJ Roelofs, S Anavi‐Goffer, L Mowat, DG Simpson, AJ Irving, ... British journal of pharmacology 160 (3), 762-771, 2010 | 184 | 2010 |
| Joint morphogenetic cells in the adult mammalian synovium AJ Roelofs, J Zupan, AHK Riemen, K Kania, S Ansboro, N White, ... Nature communications 8 (1), 15040, 2017 | 170 | 2017 |
| Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis C De Bari, AJ Roelofs Current opinion in pharmacology 40, 74-80, 2018 | 165 | 2018 |
| Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field Z Zhao, C Watt, A Karystinou, AJ Roelofs, CD McCaig, IR Gibson, ... Eur Cell Mater 22 (344), 58, 2011 | 165 | 2011 |
| Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells A Karystinou, AJ Roelofs, A Neve, FP Cantatore, H Wackerhage, ... Arthritis research & therapy 17 (1), 147-160, 2015 | 140 | 2015 |
| The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation A Guenther, S Gordon, M Tiemann, R Burger, F Bakker, JR Green, ... International Journal of Cancer 126 (1), 239-246, 2010 | 134 | 2010 |
| Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo AJ Roelofs, CA Stewart, S Sun, KM Błażewska, BA Kashemirov, ... Journal of bone and mineral research 27 (4), 835-847, 2012 | 118 | 2012 |
| Mesenchymal stem cells for the management of rheumatoid arthritis: immune modulation, repair or both? S Ansboro, AJ Roelofs, C De Bari Current opinion in rheumatology 29 (2), 201-207, 2017 | 108 | 2017 |
| Cell-based approaches to joint surface repair: a research perspective AJ Roelofs, JPJ Rocke, C De Bari Osteoarthritis and cartilage 21 (7), 892-900, 2013 | 100 | 2013 |
| Activation of γδ T cells by bisphosphonates K Thompson, AJ Roelofs, M Jauhiainen, H Mönkkönen, J Mönkkönen, ... Osteoimmunology: Interactions of the Immune and skeletal systems II, 11-20, 2010 | 90 | 2010 |
| Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S‐phase arrest, in human myeloma cells AJ Roelofs, PA Hulley, A Meijer, FH Ebetino, RGG Russell, CM Shipman International journal of cancer 119 (6), 1254-1261, 2006 | 78 | 2006 |
| The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts AC Hirbe, AJ Roelofs, DH Floyd, H Deng, SN Becker, LG Lanigan, ... Bone 44 (5), 908-916, 2009 | 77 | 2009 |
| The burden of metabolic syndrome on osteoarthritic joints BM Dickson, AJ Roelofs, JJ Rochford, HM Wilson, C De Bari Arthritis research & therapy 21, 1-10, 2019 | 70 | 2019 |
| Fluorescently labeled risedronate and related analogues:“magic linker” synthesis BA Kashemirov, JLF Bala, X Chen, FH Ebetino, Z Xia, RGG Russell, ... Bioconjugate chemistry 19 (12), 2308-2310, 2008 | 69 | 2008 |
| Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis AJ Roelofs, K Kania, AJ Rafipay, M Sambale, ST Kuwahara, FL Collins, ... Annals of the rheumatic diseases 79 (12), 1625-1634, 2020 | 66 | 2020 |
