Master transcription factors and mediator establish super-enhancers at key cell identity genes WA Whyte, DA Orlando, D Hnisz, BJ Abraham, CY Lin, MH Kagey, ... Cell 153 (2), 307-319, 2013 | 3820 | 2013 |
Super-enhancers in the control of cell identity and disease D Hnisz, BJ Abraham, TI Lee, A Lau, V Saint-André, AA Sigova, HA Hoke, ... Cell 155 (4), 934-947, 2013 | 3546 | 2013 |
Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018 | 1934 | 2018 |
A phase separation model for transcriptional control D Hnisz, K Shrinivas, RA Young, AK Chakraborty, PA Sharp Cell 169 (1), 13-23, 2017 | 1498 | 2017 |
Transcriptional addiction in cancer JE Bradner, D Hnisz, RA Young Cell 168 (4), 629-643, 2017 | 1065 | 2017 |
Activation of proto-oncogenes by disruption of chromosome neighborhoods D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ... Science 351 (6280), 1454-1458, 2016 | 1055 | 2016 |
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes JM Dowen, ZP Fan, D Hnisz, G Ren, BJ Abraham, LN Zhang, ... Cell 159 (2), 374-387, 2014 | 924 | 2014 |
YY1 is a structural regulator of enhancer-promoter loops AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ... Cell 171 (7), 1573-1588. e28, 2017 | 878 | 2017 |
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers D Hnisz, J Schuijers, CY Lin, AS Weintraub, BJ Abraham, TI Lee, ... Molecular cell 58 (2), 362-370, 2015 | 484 | 2015 |
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ... Cell 172 (5), 979-992. e6, 2018 | 459 | 2018 |
3D chromosome regulatory landscape of human pluripotent cells X Ji, DB Dadon, BE Powell, ZP Fan, D Borges-Rivera, S Shachar, ... Cell stem cell 18 (2), 262-275, 2016 | 436 | 2016 |
Insulated neighborhoods: structural and functional units of mammalian gene control D Hnisz, DS Day, RA Young Cell 167 (5), 1188-1200, 2016 | 430 | 2016 |
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas VE Clark, AS Harmancı, H Bai, MW Youngblood, TI Lee, JF Baranoski, ... Nature genetics 48 (10), 1253-1259, 2016 | 321 | 2016 |
Transcriptional dysregulation of MYC reveals common enhancer-docking mechanism J Schuijers, JC Manteiga, AS Weintraub, DS Day, AV Zamudio, D Hnisz, ... Cell reports 23 (2), 349-360, 2018 | 171 | 2018 |
Unblending of transcriptional condensates in human repeat expansion disease S Basu, SD Mackowiak, H Niskanen, D Knezevic, V Asimi, S Grosswendt, ... Cell 181 (5), 1062-1079. e30, 2020 | 139 | 2020 |
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans D Hnisz, O Majer, IE Frohner, V Komnenovic, K Kuchler PLoS pathogens 6 (5), e1000889, 2010 | 126 | 2010 |
Transcriptional loops meet chromatin: a dual‐layer network controls white–opaque switching in Candida albicans D Hnisz, T Schwarzmüller, K Kuchler Molecular microbiology 74 (1), 1-15, 2009 | 124 | 2009 |
Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms R Schulte-Sasse, S Budach, D Hnisz, A Marsico Nature Machine Intelligence 3 (6), 513-526, 2021 | 119 | 2021 |
A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequences during Candida albicans Morphogenesis D Hnisz, AF Bardet, CJ Nobile, A Petryshyn, W Glaser, U Schöck, A Stark, ... PLoS genetics 8 (12), e1003118, 2012 | 101 | 2012 |
TNFα shedding and epidermal inflammation are controlled by Jun proteins J Guinea-Viniegra, R Zenz, H Scheuch, D Hnisz, M Holcmann, L Bakiri, ... Genes & development 23 (22), 2663-2674, 2009 | 94 | 2009 |