Structure of the neurotensin receptor 1 in complex with β-arrestin 1 W Huang*, M Masureel*, Q Qu*, J Janetzko*, A Inoue, HE Kato, ... Nature 579 (7798), 303-308, 2020 | 299 | 2020 |
A small molecule that inhibits OGT activity in cells RF Ortiz-Meoz, J Jiang, MB Lazarus, M Orman, J Janetzko, C Fan, ... ACS chemical biology 10 (6), 1392-1397, 2015 | 244 | 2015 |
HCF-1 is cleaved in the active site of O-GlcNAc transferase MB Lazarus, J Jiang, V Kapuria, T Bhuiyan, J Janetzko, WF Zandberg, ... Science 342 (6163), 1235-1239, 2013 | 210 | 2013 |
Structure-based evolution of low nanomolar O-GlcNAc transferase inhibitors SES Martin, ZW Tan, HM Itkonen, DY Duveau, JA Paulo, J Janetzko, ... Journal of the American Chemical Society 140 (42), 13542-13545, 2018 | 130 | 2018 |
The making of a sweet modification: structure and function of O-GlcNAc transferase J Janetzko, S Walker Journal of Biological Chemistry 289 (50), 34424-34432, 2014 | 87 | 2014 |
Development and characterization of potent cyclic acyldepsipeptide analogues with increased antimicrobial activity JD Goodreid, J Janetzko, JP Santa Maria Jr, KS Wong, E Leung, BT Eger, ... Journal of medicinal chemistry 59 (2), 624-646, 2016 | 58 | 2016 |
Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics J Janetzko, R Kise, B Barsi-Rhyne, DH Siepe, FM Heydenreich, ... Cell 185 (24), 4560-4573. e19, 2022 | 54* | 2022 |
Indium-Promoted Chemo-and Diastereoselective Allylation of α, β-Epoxy Ketones with Potassium Allyltrifluoroborate F Nowrouzi, J Janetzko, RA Batey Organic Letters 12 (23), 5490-5493, 2010 | 38 | 2010 |
How the glycosyltransferase OGT catalyzes amide bond cleavage J Janetzko, SA Trauger, MB Lazarus, S Walker Nature chemical biology 12 (11), 899-901, 2016 | 36 | 2016 |
Organoboron-Based Allylation Approach to the Total Synthesis of the Medium-Ring Dilactone (+)-Antimycin A1b J Janetzko, RA Batey The Journal of Organic Chemistry 79 (16), 7415-7424, 2014 | 26 | 2014 |
Protein substrates engage the lumen of O-GlcNAc transferase’s tetratricopeptide repeat domain in different ways CM Joiner, FA Hammel, J Janetzko, S Walker Biochemistry 60 (11), 847-853, 2021 | 23 | 2021 |
Palladium β-diiminate chemistry: Reactivity towards monodentate ligands and arylboronic acids VT Annibale, R Tan, J Janetzko, LM Lund, D Song Inorganica Chimica Acta 380, 308-321, 2012 | 17 | 2012 |
Aspartate glycosylation triggers isomerization to isoaspartate J Janetzko, S Walker Journal of the American Chemical Society 139 (9), 3332-3335, 2017 | 16 | 2017 |
Novel dinuclear and trinuclear palladium β-diiminate complexes containing amido–chloro double-bridges A Hadzovic, J Janetzko, D Song Dalton Transactions, 3279-3281, 2008 | 13 | 2008 |
How membranes shape the β-arrestin conformational landscape to provide spatiotemporal control of GPCR desensitization and trafficking J Janetzko, R Shivnaraine, JC Deutsch, Y Shi, W Liu, M Masureel, S Chu, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Dissecting OGT’s TPR domain to identify determinants of cellular function SC Potter, BE Gibbs, FA Hammel, CM Joiner, JA Paulo, J Janetzko, ... Proceedings of the National Academy of Sciences 121 (22), e2401729121, 2024 | | 2024 |
Arrestin C-tail dynamics regulate activation and GPCR engagement J Janetzko, A Inoue, Y Shi, JC Deutsch, KK Ray, M Masureel, ... Biophysical Journal 122 (3), 49a, 2023 | | 2023 |
Viewpoint on the Second Transatlantic GPCR Symposium for Early Career Investigators J Janetzko, CP Johnson, P Morales, MM Scharf ACS Pharmacology & Translational Science 6 (1), 195-199, 2022 | | 2022 |
Developing new tools for the study of O-GlcNAc transferase in disease S Martin, D Duveau, J Janetzko, Z Tan, F Moss, H Itkonen, P Sliz, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
OGT Catalyzes Three Distinct Post-Translational Modifications via Glycosylation JC Janetzko Harvard University, 2017 | | 2017 |