Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms T Aoki, J Frȍsen, M Fukuda, K Bando, G Shioi, K Tsuji, E Ollikainen, ... Science signaling 10 (465), eaah6037, 2017 | 179 | 2017 |
BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF HH Pulkkinen, M Kiema, JP Lappalainen, A Toropainen, M Beter, ... Angiogenesis 24, 129-144, 2021 | 120 | 2021 |
Baculovirus entry into human hepatoma cells H Matilainen, J Rinne, L Gilbert, V Marjomäki, H Reunanen, ... Journal of virology 79 (24), 15452-15459, 2005 | 100 | 2005 |
Internalization of novel non-viral vector TAT-streptavidin into human cells J Rinne, B Albarran, J Jylhävä, TO Ihalainen, P Kankaanpää, VP Hytönen, ... BMC biotechnology 7, 1-14, 2007 | 90 | 2007 |
Improvement in nuclear entry and transgene expression of baculoviruses by disintegration of microtubules in human hepatocytes M Salminen, KJ Airenne, R Rinnankoski, J Reimari, O Välilehto, J Rinne, ... Journal of virology 79 (5), 2720-2728, 2005 | 80 | 2005 |
Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells JP Laakkonen, AR Mäkelä, E Kakkonen, P Turkki, S Kukkonen, J Peränen, ... PLoS One 4 (4), e5093, 2009 | 60 | 2009 |
6-O- and N-Sulfated Syndecan-1 Promotes Baculovirus Binding and Entry into Mammalian Cells KE Makkonen, P Turkki, JP Laakkonen, S Ylä-Herttuala, V Marjomäki, ... Journal of Virology 87 (20), 11148-11159, 2013 | 52 | 2013 |
Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction T Vuorio, E Ylä-Herttuala, JP Laakkonen, S Laidinen, T Liimatainen, ... Scientific reports 8 (1), 16709, 2018 | 45 | 2018 |
Baculovirus‐mediated immediate‐early gene expression and nuclear reorganization in human cells JP Laakkonen, MU Kaikkonen, PHA Ronkainen, TO Ihalainen, ... Cellular microbiology 10 (3), 667-681, 2008 | 45 | 2008 |
Beyond endothelial cells: vascular endothelial growth factors in heart, vascular anomalies and placenta JP Laakkonen, J Lähteenvuo, S Jauhiainen, T Heikura, S Ylä-Herttuala Vascular pharmacology 112, 91-101, 2019 | 44 | 2019 |
Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8 JP Laakkonen, JP Lappalainen, TL Theelen, PI Toivanen, T Nieminen, ... Angiogenesis 20, 109-124, 2017 | 43 | 2017 |
Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice MP Turunen, T Husso, H Musthafa, S Laidinen, G Dragneva, ... PLoS One 9 (2), e89979, 2014 | 37 | 2014 |
Tumor targeting of baculovirus displaying a lymphatic homing peptide AR Mäkelä, J Enbäck, JP Laakkonen, M Vihinen‐Ranta, P Laakkonen, ... The Journal of Gene Medicine 10 (9), 1019-1031, 2008 | 35 | 2008 |
Coxsackievirus B3-induced cellular protrusions: structural characteristics and functional competence O Paloheimo, TO Ihalainen, S Tauriainen, O Välilehto, S Kirjavainen, ... Journal of virology 85 (13), 6714-6724, 2011 | 33 | 2011 |
Dynamics and interactions of parvoviral NS1 protein in the nucleus TO Ihalainen, EA Niskanen, J Jylhävä, T Turpeinen, J Rinne, J Timonen, ... Cellular microbiology 9 (8), 1946-1959, 2007 | 31 | 2007 |
Recent advancements in cardiovascular gene therapy and vascular biology JP Laakkonen, S Ylä-Herttuala Human gene therapy 26 (8), 518-524, 2015 | 29 | 2015 |
Sleeping Beauty–baculovirus hybrid vectors for long‐term gene expression in the eye TAK Turunen, JP Laakkonen, L Alasaarela, KJ Airenne, S Ylä‐Herttuala The journal of gene medicine 16 (1-2), 40-53, 2014 | 29 | 2014 |
Hypoxia-mediated regulation of histone demethylases affects angiogenesis-associated functions in endothelial cells OHF Liu, M Kiema, M Beter, S Ylä-Herttuala, JP Laakkonen, ... Arteriosclerosis, thrombosis, and vascular biology 40 (11), 2665-2677, 2020 | 27 | 2020 |
Wall shear stress predicts media degeneration and biomechanical changes in thoracic aorta M Kiema, JK Sarin, SP Kauhanen, J Torniainen, H Matikka, ES Luoto, ... Frontiers in Physiology 13, 934941, 2022 | 25 | 2022 |
Culture medium induced vimentin reorganization associates with enhanced baculovirus-mediated gene delivery AJ Mähönen, KE Makkonen, JP Laakkonen, TO Ihalainen, SP Kukkonen, ... Journal of biotechnology 145 (2), 111-119, 2010 | 22 | 2010 |