Context specificity of the EMT transcriptional response DP Cook, BC Vanderhyden Nature communications 11 (1), 2142, 2020 | 177 | 2020 |
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells S Robichaud, G Fairman, V Vijithakumar, E Mak, DP Cook, AR Pelletier, ... Autophagy 17 (11), 3671-3689, 2021 | 105 | 2021 |
Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage M Hurskainen, I Mižíková, DP Cook, N Andersson, C Cyr-Depauw, ... Nature communications 12 (1), 1565, 2021 | 105 | 2021 |
Metformin abrogates age-associated ovarian fibrosis CW McCloskey, DP Cook, BS Kelly, F Azzi, CH Allen, A Forsyth, J Upham, ... Clinical Cancer Research 26 (3), 632-642, 2020 | 62 | 2020 |
When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer MS Hasim, M Marotel, JJ Hodgins, E Vulpis, OJ Makinson, S Asif, HY Shih, ... Science Advances 8 (15), eabj3286, 2022 | 50 | 2022 |
Ovarian cancer and the evolution of subtype classifications using transcriptional profiling DP Cook, BC Vanderhyden Biology of reproduction 101 (3), 645-658, 2019 | 47 | 2019 |
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice D Karunakaran, AW Turner, AC Duchez, S Soubeyrand, A Rasheed, ... Nature metabolism 2 (10), 1113-1125, 2020 | 40 | 2020 |
Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice DA Landry, E Yakubovich, DP Cook, S Fasih, J Upham, BC Vanderhyden Science Advances 8 (35), eabq1475, 2022 | 38 | 2022 |
The evolution and functional diversification of the deubiquitinating enzyme superfamily C Vlasschaert, D Cook, X Xia, DA Gray Genome Biology and Evolution 9 (3), 558-573, 2017 | 36 | 2017 |
Transcriptional census of epithelial-mesenchymal plasticity in cancer DP Cook, BC Vanderhyden Science advances 8 (1), eabi7640, 2022 | 35 | 2022 |
Single-cell transcriptomic analysis of neuroepithelial cells and other cell types of the gills of zebrafish (Danio rerio) exposed to hypoxia W Pan, RS Godoy, DP Cook, AL Scott, CA Nurse, MG Jonz Scientific Reports 12 (1), 10144, 2022 | 31 | 2022 |
Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium NH Vuong*, DP Cook*, LA Forrest, LE Carter, P Robineau-Charette, ... PLoS genetics 14 (11), e1007788, 2018 | 18 | 2018 |
A specialist-generalist framework for epithelial-mesenchymal plasticity in cancer DP Cook, JL Wrana Trends in Cancer 8 (5), 358-368, 2022 | 16 | 2022 |
Periostin gene expression in neu-positive breast cancer cells is regulated by a FGFR signaling cross talk with TGFβ/PI3K/AKT pathways C Labrèche, DP Cook, J Abou-Hamad, J Pascoal, BR Pryce, ... Breast Cancer Research 23, 1-14, 2021 | 16 | 2021 |
Assessing the efficacy of androgen receptor and Sox10 as independent markers of the triple-negative breast cancer subtype by transcriptome profiling KN Al-Zahrani, DP Cook, BC Vanderhyden, LA Sabourin Oncotarget 9 (70), 33348, 2018 | 16 | 2018 |
The tumor immune profile of murine ovarian cancer models: an essential tool for ovarian cancer immunotherapy research GM Rodriguez, KJC Galpin, DP Cook, E Yakubovich, V Maranda, ... Cancer research communications 2 (6), 417-433, 2022 | 11 | 2022 |
Single-cell RNA sequencing-based characterization of resident lung mesenchymal stromal cells in bronchopulmonary dysplasia I Mižíková, F Lesage, C Cyr-Depauw, DP Cook, M Hurskainen, ... Stem Cells 40 (5), 479-492, 2022 | 11 | 2022 |
COX2 is induced in the ovarian epithelium during ovulatory wound repair and promotes cell survival LE Carter, DP Cook, O Collins, LF Gamwell, HA Dempster, HW Wong, ... Biology of Reproduction 101 (5), 961-974, 2019 | 11 | 2019 |
Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells YK Kim, B Cho, DP Cook, D Trcka, JL Wrana, M Ramalho-Santos Cell Reports 42 (1), 2023 | 10 | 2023 |
Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation RS Godoy, ND Cober, DP Cook, E McCourt, Y Deng, L Wang, ... Elife 12, e80900, 2023 | 9 | 2023 |