The vascular smooth muscle cell: a therapeutic target in Type 2 diabetes? KE Porter, K Riches Clinical science 125 (4), 167-182, 2013 | 110 | 2013 |
Lipoprotein (a): cellular effects and molecular mechanisms K Riches, KE Porter Cholesterol 2012, 2012 | 86 | 2012 |
Inherent differences in morphology, proliferation, and migration in saphenous vein smooth muscle cells cultured from nondiabetic and Type 2 diabetic patients HA Madi, K Riches, P Warburton, DJ O'Regan, NA Turner, KE Porter American Journal of Physiology-Cell Physiology 297 (5), C1307-C1317, 2009 | 81 | 2009 |
Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein RS Mughal, JL Scragg, P Lister, P Warburton, K Riches, DJ O’Regan, ... Diabetologia 53 (8), 1761-1771, 2010 | 80 | 2010 |
Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1. 3 channel blockers A Cheong, J Li, P Sukumar, B Kumar, F Zeng, K Riches, C Munsch, ... Cardiovascular research 89 (2), 282-289, 2011 | 79 | 2011 |
Exploring smooth muscle phenotype and function in a bioreactor model of abdominal aortic aneurysm K Riches, TG Angelini, GS Mudhar, J Kaye, E Clark, MA Bailey, S Sohrabi, ... Journal of translational medicine 11 (1), 208, 2013 | 75 | 2013 |
Therapeutic Targeting of the Proinflammatory IL-6-JAK/STAT Signalling Pathways Responsible for Vascular Restenosis in Type 2 Diabetes Mellitus FT Moshapa, K Riches-Suman, TM Palmer Cardiology Research and Practice 2019, 2019 | 71 | 2019 |
Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function K Riches, AR Alshanwani, P Warburton, DJ O’Regan, SG Ball, IC Wood, ... Journal of molecular and cellular cardiology 74, 240-250, 2014 | 71 | 2014 |
Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids. E Al-Shawaf, J Naylor, H Taylor, K Riches, CJ Milligan, D O'regan, ... Arteriosclerosis, thrombosis, and vascular biology 30 (7), 1453-1459, 2010 | 55 | 2010 |
Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts K Riches, ME Morley, NA Turner, DJ O'Regan, SG Ball, C Peers, ... Journal of molecular and cellular cardiology 47 (3), 391-399, 2009 | 55 | 2009 |
Investigating inherent functional differences between human cardiac fibroblasts cultured from nondiabetic and Type 2 diabetic donors B Sedgwick, K Riches, SA Bageghni, DJ O’Regan, KE Porter, NA Turner Cardiovascular Pathology 23 (4), 204-210, 2014 | 53 | 2014 |
Dermal fibroblasts cultured from donors with type 2 diabetes mellitus retain an epigenetic memory associated with poor wound healing responses AHA Al-Rikabi, DJ Tobin, K Riches-Suman, MJ Thornton Scientific reports 11 (1), 1474, 2021 | 52 | 2021 |
Progressive development of aberrant smooth muscle cell phenotype in abdominal aortic aneurysm disease K Riches, E Clark, RJ Helliwell, TG Angelini, KE Hemmings, MA Bailey, ... Journal of vascular research 55 (1), 35-46, 2018 | 48 | 2018 |
Linking energy sensing to suppression of JAK-STAT signalling: a potential route for repurposing AMPK activators? C Speirs, JJL Williams, K Riches, IP Salt, TM Palmer Pharmacological Research, 2017 | 40 | 2017 |
Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing LV Trevor, K Riches-Suman, AL Mahajan, MJ Thornton Journal of Clinical Medicine 9 (7), 2161, 2020 | 36 | 2020 |
CCAAT/enhancer binding protein α, β and δ gene variants: associations with obesity related phenotypes in the Leeds Family Study CE Bennett, J Nsengimana, JA Bostock, C Cymbalista, TS Futers, ... Diabetes and Vascular Disease Research 7 (3), 195-203, 2010 | 36 | 2010 |
Type 2 diabetes impairs venous, but not arterial smooth muscle cell function: possible role of differential RhoA activity K Riches, P Warburton, DJ O’Regan, NA Turner, KE Porter Cardiovascular Revascularization Medicine 15 (3), 141-148, 2014 | 30 | 2014 |
Apolipoprotein (a) acts as a chemorepellent to human vascular smooth muscle cells via integrin α V β 3 and RhoA/ROCK-mediated mechanisms K Riches, L Franklin, A Maqbool, M Peckham, M Adams, J Bond, ... The international journal of biochemistry & cell biology 45 (8), 1776-1783, 2013 | 30 | 2013 |
Hypoxic inhibition of human cardiac fibroblast invasion and MMP-2 activation may impair adaptive myocardial remodelling ME Morley, K Riches, C Peers, KE Porter Biochemical Society Transactions 35 (5), 905-907, 2007 | 30 | 2007 |
Emerging roles of protein O-GlcNAcylation in cardiovascular diseases: insights and novel therapeutic targets IO Bolanle, K Riches-Suman, R Williamson, TM Palmer Pharmacological Research 165, 105467, 2021 | 23 | 2021 |