Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-κB K Gowrishankar, D Gunatilake, SJ Gallagher, J Tiffen, H Rizos, P Hersey PloS one 10 (4), e0123410, 2015 | 246 | 2015 |
Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma MS Carlino, JR Todd, K Gowrishankar, B Mijatov, GM Pupo, C Fung, ... Molecular oncology 8 (3), 544-554, 2014 | 139 | 2014 |
Disturbed CD4+ T Cell Homeostasis and In Vitro HIV-1 Susceptibility in Transgenic Mice Expressing T Cell Line–tropic HIV-1 Receptors S Sawada, K Gowrishankar, R Kitamura, M Suzuki, G Suzuki, S Tahara, ... The Journal of experimental medicine 187 (9), 1439-1449, 1998 | 128 | 1998 |
Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells KP Micklethwaite, K Gowrishankar, BS Gloss, Z Li, JA Street, L Moezzi, ... Blood, The Journal of the American Society of Hematology 138 (16), 1391-1405, 2021 | 119 | 2021 |
Acquired resistance to BRAF inhibition can confer cross-resistance to combined BRAF/MEK inhibition K Gowrishankar, S Snoyman, GM Pupo, TM Becker, RF Kefford, H Rizos Journal of investigative dermatology 132 (7), 1850-1859, 2012 | 109 | 2012 |
Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling A Heinemann, C Cullinane, R De Paoli-Iseppi, JS Wilmott, D Gunatilake, ... Oncotarget 6 (25), 21507, 2015 | 98 | 2015 |
Control of NF‐kB activity in human melanoma by bromodomain and extra‐terminal protein inhibitor I‐BET 151 SJ Gallagher, B Mijatov, D Gunatilake, K Gowrishankar, J Tiffen, W James, ... Pigment cell & melanoma research 27 (6), 1126-1137, 2014 | 98 | 2014 |
Antiproliferative effects of continued mitogen-activated protein kinase pathway inhibition following acquired resistance to BRAF and/or MEK inhibition in melanoma MS Carlino, K Gowrishankar, CAB Saunders, GM Pupo, S Snoyman, ... Molecular cancer therapeutics 12 (7), 1332-1342, 2013 | 86 | 2013 |
Characterization of the host immune response in human ganglia after herpes zoster K Gowrishankar, M Steain, AL Cunningham, M Rodriguez, P Blumbergs, ... Journal of virology 84 (17), 8861-8870, 2010 | 83 | 2010 |
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes JC Tiffen, D Gunatilake, SJ Gallagher, K Gowrishankar, A Heinemann, ... Oncotarget 6 (29), 27023, 2015 | 80 | 2015 |
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor TM Becker, SC Boyd, B Mijatov, K Gowrishankar, S Snoyman, GM Pupo, ... Oncogene 33 (9), 1158-1166, 2014 | 76 | 2014 |
The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells SJ Gallagher, B Mijatov, D Gunatilake, JC Tiffen, K Gowrishankar, L Jin, ... Journal of Investigative Dermatology 134 (11), 2795-2805, 2014 | 68 | 2014 |
Absence of distinguishing senescence traits in human melanocytic nevi SL Tran, S Haferkamp, LL Scurr, K Gowrishankar, TM Becker, C Desilva, ... Journal of Investigative Dermatology 132 (9), 2226-2234, 2012 | 64 | 2012 |
Oncogenic B-RAFV600E signaling induces the T-box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion SC Boyd, B Mijatov, GM Pupo, SL Tran, K Gowrishankar, HM Shaw, ... Journal of Investigative Dermatology 133 (5), 1269-1277, 2013 | 58 | 2013 |
Upregulation of CXCL10 in human dorsal root ganglia during experimental and natural varicella-zoster virus infection M Steain, K Gowrishankar, M Rodriguez, B Slobedman, A Abendroth Journal of virology 85 (1), 626-631, 2011 | 55 | 2011 |
Release of a membrane-bound death domain by γ-secretase processing of the p75NTR homolog NRADD K Gowrishankar, MG Zeidler, C Vincenz Journal of Cell Science 117 (18), 4099-4111, 2004 | 50 | 2004 |
Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells K Gowrishankar, L Birtwistle, K Micklethwaite Mammalian Genome 29, 739-756, 2018 | 46 | 2018 |
NRADD, a novel membrane protein with a death domain involved in mediating apoptosis in response to ER stress X Wang, Z Shao, FS Zetoune, MG Zeidler, K Gowrishankar, C Vincenz Cell Death & Differentiation 10 (5), 580-591, 2003 | 39 | 2003 |
Productive varicella-zoster virus infection of cultured intact human ganglia K Gowrishankar, B Slobedman, AL Cunningham, M Miranda-Saksena, ... Journal of virology 81 (12), 6752-6756, 2007 | 38 | 2007 |
CAR T cell generation by piggyBac transposition from linear doggybone DNA vectors requires transposon DNA-flanking regions DC Bishop, L Caproni, K Gowrishankar, M Legiewicz, K Karbowniczek, ... Molecular Therapy-Methods & Clinical Development 17, 359-368, 2020 | 27 | 2020 |