Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance N Gonen, YG Assaraf Drug Resistance Updates 15 (4), 183-210, 2012 | 518 | 2012 |
Sex reversal following deletion of a single distal enhancer of Sox9 N Gonen, CR Futtner, S Wood, SA Garcia-Moreno, IM Salamone, ... Science 360 (6396), 1469-1473, 2018 | 198 | 2018 |
Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest S Raz, D Sheban, N Gonen, M Stark, B Berman, YG Assaraf Cell death & disease 5 (2), e1067-e1067, 2014 | 75 | 2014 |
Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone N Gonen, A Quinn, HC O’Neill, P Koopman, R Lovell-Badge PLoS genetics 13 (1), e1006520, 2017 | 68 | 2017 |
The regulation of Sox9 expression in the gonad N Gonen, R Lovell-Badge Current topics in developmental biology 134, 223-252, 2019 | 61 | 2019 |
Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene C Eozenou, N Gonen, MS Touzon, A Jorgensen, SA Yatsenko, L Fusee, ... Proceedings of the National Academy of Sciences 117 (24), 13680-13688, 2020 | 55 | 2020 |
PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells N Gonen, EE Bram, YG Assaraf Biochemical and biophysical research communications 376 (4), 787-792, 2008 | 54 | 2008 |
The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1 N Gonen, YG Assaraf Journal of Biological Chemistry 285 (44), 33602-33613, 2010 | 48 | 2010 |
Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination SA Garcia-Moreno, CR Futtner, IM Salamone, N Gonen, R Lovell-Badge, ... Developmental biology 446 (2), 168-179, 2019 | 39 | 2019 |
Functional elements in the minimal promoter of the human proton-coupled folate transporter M Stark, N Gonen, YG Assaraf Biochemical and biophysical research communications 388 (1), 79-85, 2009 | 28 | 2009 |
SOX genes and their role in disorders of sex development R Sreenivasan, N Gonen, A Sinclair Sexual Development 16 (2-3), 80-91, 2022 | 18 | 2022 |
In vitro cellular reprogramming to model gonad development and its disorders N Gonen, C Eozenou, R Mitter, M Elzaiat, I Stévant, R Aviram, ... Science Advances 9 (1), eabn9793, 2023 | 16 | 2023 |
Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone N Gonen, A Quinn, HC O’Neill, P Koopman, R Lovell-Badge PLoS genetics 13 (2), e1006584, 2017 | 12 | 2017 |
Epigenetic aging of mammalian gametes M Klutstein, N Gonen Molecular Reproduction and Development 90 (12), 785-803, 2023 | 5 | 2023 |
Cis-regulatory control of mammalian sex determination M Ridnik, S Schoenfelder, N Gonen Sexual Development 15 (5-6), 317-334, 2021 | 5 | 2021 |
Homothorax plays autonomous and nonautonomous roles in proximodistal axis formation and migration of the Drosophila renal tubules A Zohar‐Stoopel, N Gonen, M Mahroum, DS Ben‐Zvi, H Toledano, ... Developmental Dynamics 243 (1), 132-144, 2014 | 4 | 2014 |
Towards a “Testis in a Dish”: Generation of Mouse Testicular Organoids that Recapitulate Testis Structure and Expression Profiles A Stopel, C Lev, S Dahari, O Adibi, L Armon, N Gonen International Journal of Biological Sciences 20 (3), 1024, 2024 | 2 | 2024 |
Regulation of Sox9 in the gonad during sex determination R Lovell-Badge, N Gonen, S Samson, H O'Neill, R Sekido, D Maatouk Transgenic Research 25 (2), 216, 2016 | 1 | 2016 |
Two redundant transcription factor binding sites in a single enhancer are essential for mammalian sex determination M Ridnik, E Abberbock, V Alipov, SZ Lhermann, S Kaufman, M Lubman, ... Nucleic Acids Research 52 (10), 5514-5528, 2024 | | 2024 |
Transposable elements acquire time-and sex-specific transcriptional and epigenetic signatures along mouse fetal gonad development I Stévant, N Gonen, F Poulat Frontiers in Cell and Developmental Biology 11, 1327410, 2024 | | 2024 |