Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis QT Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao ... Nature Medicine, 2019 | 591 | 2019 |
Metabolic network failures in Alzheimer's disease: A biochemical road map JB Toledo, M Arnold, G Kastenmüller, R Chang, RA Baillie, X Han, ... Alzheimer's & Dementia 13 (9), 965-984, 2017 | 408 | 2017 |
Analysis of transcriptional variability in a large human iPSC library reveals genetic and non-genetic determinants of heterogeneity I Carcamo-Orive, GE Hoffman, P Cundiff, ND Beckmann, SL D’Souza, ... Cell stem cell 20 (4), 518-532. e9, 2017 | 241 | 2017 |
Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome M Arnold, K Nho, A Kueider-Paisley, T Massaro, K Huynh, B Brauner, ... Nature communications 11 (1), 1148, 2020 | 144 | 2020 |
Metabolic network analysis reveals altered bile acid synthesis and metabolism in Alzheimer’s disease P Baloni, CC Funk, J Yan, JT Yurkovich, A Kueider-Paisley, K Nho, ... Cell Reports Medicine 1 (8), 2020 | 135 | 2020 |
Systematic search for recipes to generate induced pluripotent stem cells R Chang, R Shoemaker, W Wang PLoS computational biology 7 (12), e1002300, 2011 | 73 | 2011 |
Elevated rates of transaminitis during ipilimumab therapy for metastatic melanoma SG Bernardo, M Moskalenko, M Pan, S Shah, HK Sidhu, S Sicular, ... Melanoma research 23 (1), 47-54, 2013 | 65 | 2013 |
Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II–III resectable disease S Sivendran, R Chang, L Pham, RG Phelps, ST Harcharik, LD Hall, ... Journal of Investigative Dermatology 134 (8), 2202-2211, 2014 | 63 | 2014 |
Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy Acta Neuropathologica 136 (5), 709–727, 2018 | 53 | 2018 |
A novel knowledge-driven systems biology approach for phenotype prediction upon genetic intervention R Chang, R Shoemaker, W Wang IEEE/ACM Transactions on Computational Biology and Bioinformatics 8 (5 …, 2011 | 50 | 2011 |
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target VA Petyuk, R Chang, M Ramirez-Restrepo, ND Beckmann, MYR Henrion, ... Brain 141 (9), 2721-2739, 2018 | 40 | 2018 |
Modeling semantics of inconsistent qualitative knowledge for quantitative Bayesian network inference R Chang, W Brauer, M Stetter Neural Networks 21 (2-3), 182-192, 2008 | 35 | 2008 |
Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro MP Cadiz, TD Jensen, JP Sens, K Zhu, WM Song, B Zhang, M Ebbert, ... Molecular Neurodegeneration 17 (1), 26, 2022 | 34 | 2022 |
Novel algorithm for Bayesian network parameter learning with informative prior constraints R Chang, W Wang The 2010 international joint conference on neural networks (IJCNN), 1-8, 2010 | 31 | 2010 |
Quantitative inference by qualitative semantic knowledge mining with Bayesian model averaging R Chang, M Stetter, W Brauer IEEE transactions on knowledge and data engineering 20 (12), 1587-1600, 2008 | 30 | 2008 |
Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas EH de Moll, Y Fu, Y Qian, SH Perkins, S Wieder, S Gnjatic, R Remark, ... Cancer Immunology, Immunotherapy 64, 1193-1203, 2015 | 26 | 2015 |
Automated digital TIL analysis (ADTA) adds prognostic value to standard assessment of depth and ulceration in primary melanoma MR Moore, ID Friesner, EM Rizk, BT Fullerton, M Mondal, MH Trager, ... Scientific reports 11 (1), 2809, 2021 | 23 | 2021 |
Exploring the reproducibility of probabilistic causal molecular network models A Cohain, AA Divaraniya, K Zhu, JR Scarpa, A Kasarskis, J Zhu, R Chang, ... PSB, 120-131, 2017 | 23 | 2017 |
Linking transcriptomic and imaging data defines features of a favorable tumor immune microenvironment and identifies a combination biomarker for primary melanoma RD Gartrell-Corrado, AX Chen, EM Rizk, DK Marks, MH Bogardus, ... Cancer research 80 (5), 1078-1087, 2020 | 22 | 2020 |
Causal inference in biology networks with integrated belief propagation R Chang, JR Karr, EE Schadt Pacific Symposium on Biocomputing Co-Chairs, 359-370, 2014 | 22 | 2014 |