A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62 A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ... Molecular and cellular biology 30 (13), 3275-3285, 2010 | 874 | 2010 |
Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response W Chen, Z Sun, XJ Wang, T Jiang, Z Huang, D Fang, DD Zhang Molecular cell 34 (6), 663-673, 2009 | 703 | 2009 |
Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism D Ren, NF Villeneuve, T Jiang, T Wu, A Lau, HA Toppin, DD Zhang Proceedings of the National Academy of Sciences 108 (4), 1433-1438, 2011 | 668 | 2011 |
p62 links autophagy and Nrf2 signaling T Jiang, B Harder, MR De La Vega, PK Wong, E Chapman, DD Zhang Free Radical Biology and Medicine 88, 199-204, 2015 | 550 | 2015 |
The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy T Jiang, Z Huang, Y Lin, Z Zhang, D Fang, DD Zhang Diabetes 59 (4), 850-860, 2010 | 501 | 2010 |
PARP inhibition elicits STING-dependent antitumor immunity in Brca1-deficient ovarian cancer L Ding, HJ Kim, Q Wang, M Kearns, T Jiang, CE Ohlson, BB Li, S Xie, ... Cell reports 25 (11), 2972-2980. e5, 2018 | 448 | 2018 |
Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-N2-(2-isopropoxy-5 … TH Marsilje, W Pei, B Chen, W Lu, T Uno, Y Jin, T Jiang, S Kim, N Li, ... Journal of medicinal chemistry 56 (14), 5675-5690, 2013 | 445 | 2013 |
High levels of Nrf2 determine chemoresistance in type II endometrial cancer T Jiang, N Chen, F Zhao, XJ Wang, B Kong, W Zheng, DD Zhang Cancer research 70 (13), 5486-5496, 2010 | 317 | 2010 |
Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I T Jiang, KL Kuhen, K Wolff, H Yin, K Bieza, J Caldwell, B Bursulaya, ... Bioorganic & medicinal chemistry letters 16 (8), 2105-2108, 2006 | 294 | 2006 |
Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response T Jiang, F Tian, H Zheng, SA Whitman, Y Lin, Z Zhang, N Zhang, ... Kidney international 85 (2), 333-343, 2014 | 243 | 2014 |
Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2 T Jiang, KL Kuhen, K Wolff, H Yin, K Bieza, J Caldwell, B Bursulaya, ... Bioorganic & medicinal chemistry letters 16 (8), 2109-2112, 2006 | 236 | 2006 |
The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells W GT, NF Villeneuve, SD Lamore, AS Bause, T Jiang, DD Zhang Molecules 15 (5), 3338-3355, 2010 | 205 | 2010 |
An essential role of NRF2 in diabetic wound healing M Long, M Rojo de la Vega, Q Wen, M Bharara, T Jiang, R Zhang, S Zhou, ... Diabetes 65 (3), 780-793, 2016 | 198 | 2016 |
Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention B Harder, T Jiang, T Wu, S Tao, MR de la Vega, W Tian, E Chapman, ... Biochemical Society Transactions 43 (4), 680-686, 2015 | 179 | 2015 |
Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer L Ji, H Li, P Gao, G Shang, DD Zhang, N Zhang, T Jiang PloS one 8 (5), e63404, 2013 | 173 | 2013 |
Nrf2 promotes neuronal cell differentiation F Zhao, T Wu, A Lau, T Jiang, Z Huang, XJ Wang, W Chen, PK Wong, ... Free Radical Biology and Medicine 47 (6), 867-879, 2009 | 122 | 2009 |
Does Nrf2 contribute to p53-mediated control of cell survival and death? W Chen, T Jiang, H Wang, S Tao, A Lau, D Fang, DD Zhang Antioxidants & redox signaling 17 (12), 1670-1675, 2012 | 121 | 2012 |
Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway G Shang, X Tang, P Gao, F Guo, H Liu, Z Zhao, Q Chen, T Jiang, N Zhang, ... The Journal of Nutritional Biochemistry 26 (6), 596-606, 2015 | 114 | 2015 |
GelMA/PEGDA microneedles patch loaded with HUVECs-derived exosomes and Tazarotene promote diabetic wound healing M Yuan, K Liu, T Jiang, S Li, J Chen, Z Wu, W Li, R Tan, W Wei, X Yang, ... Journal of nanobiotechnology 20 (1), 147, 2022 | 110 | 2022 |
Nrf2 protects against As (III)-induced damage in mouse liver and bladder T Jiang, Z Huang, JY Chan, DD Zhang Toxicology and applied pharmacology 240 (1), 8-14, 2009 | 109 | 2009 |