Activated p53 suppresses the histone methyltransferase EZH2 gene X Tang, M Milyavsky, I Shats, N Erez, N Goldfinger, V Rotter Oncogene 23 (34), 5759-5769, 2004 | 255 | 2004 |
A joint analysis of metabolomics and genetics of breast cancer X Tang, CC Lin, I Spasojevic, ES Iversen, JT Chi, JR Marks Breast cancer research 16, 1-15, 2014 | 214 | 2014 |
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress G LaMonte, X Tang, JLY Chen, J Wu, CKC Ding, MM Keenan, ... Cancer & metabolism 1, 1-19, 2013 | 204 | 2013 |
p53-dependent down-regulation of telomerase is mediated by p21waf1 I Shats, M Milyavsky, X Tang, P Stambolsky, N Erez, R Brosh, I Kogan, ... Journal of Biological Chemistry 279 (49), 50976-50985, 2004 | 201 | 2004 |
Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype M Milyavsky, I Shats, N Erez, X Tang, S Senderovich, A Meerson, ... Cancer research 63 (21), 7147-7157, 2003 | 191 | 2003 |
The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA H Offer, N Erez, I Zurer, X Tang, M Milyavsky, N Goldfinger, V Rotter Carcinogenesis 23 (6), 1025-1032, 2002 | 165 | 2002 |
Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs X Tang, JE Lucas, JLY Chen, G LaMonte, J Wu, MC Wang, C Koumenis, ... Cancer research 72 (2), 491-502, 2012 | 114 | 2012 |
Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis X Tang, MM Keenan, J Wu, CA Lin, L Dubois, JW Thompson, ... PLoS genetics 11 (4), e1005158, 2015 | 98 | 2015 |
Cystine deprivation triggers programmed necrosis in VHL-deficient renal cell carcinomas X Tang, J Wu, CK Ding, M Lu, MM Keenan, CC Lin, CA Lin, CC Wang, ... Cancer research 76 (7), 1892-1903, 2016 | 88 | 2016 |
Leptin signaling mediates obesity-associated CSC enrichment and EMT in preclinical TNBC models LW Bowers, EL Rossi, SB McDonell, SS Doerstling, SA Khatib, ... Molecular Cancer Research 16 (5), 869-879, 2018 | 74 | 2018 |
Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation M Milyavsky, Y Tabach, I Shats, N Erez, Y Cohen, X Tang, M Kalis, ... Cancer research 65 (11), 4530-4543, 2005 | 72 | 2005 |
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway CC Lin, WH Yang, YT Lin, X Tang, PH Chen, CKC Ding, DC Qu, ... Oncogene 40 (11), 2018-2034, 2021 | 63 | 2021 |
Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling X Tang, CK Ding, J Wu, J Sjol, S Wardell, I Spasojevic, D George, ... Oncogene 36 (30), 4235-4242, 2017 | 62 | 2017 |
Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate–induced death by attenuating activating transcription factor 3 induction Y Buganim, E Kalo, R Brosh, H Besserglick, I Nachmany, Y Rais, ... Cancer research 66 (22), 10750-10759, 2006 | 44 | 2006 |
ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate MM Keenan, B Liu, X Tang, J Wu, D Cyr, RD Stevens, O Ilkayeva, ... PLoS genetics 11 (10), e1005599, 2015 | 43 | 2015 |
RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence CC Lin, NW Mabe, YT Lin, WH Yang, X Tang, L Hong, T Sun, J Force, ... Cell Death & Differentiation 27 (7), 2234-2247, 2020 | 42 | 2020 |
Single-cell analysis reveals distinct gene expression and heterogeneity in male and female Plasmodium falciparum gametocytes KA Walzer, DM Kubicki, X Tang, JTA Chi MSphere 3 (2), 10.1128/msphere. 00130-18, 2018 | 41* | 2018 |
Amyloid-β precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress X Tang, M Milyavsky, N Goldfinger, V Rotter Oncogene 26 (52), 7302-7312, 2007 | 40 | 2007 |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation CC Lin, M Kitagawa, X Tang, MH Hou, J Wu, DC Qu, V Srinivas, X Liu, ... Nature communications 9 (1), 1039, 2018 | 38 | 2018 |
HDAC6 inhibitors sensitize non-mesenchymal triple-negative breast cancer cells to cysteine deprivation T Alothaim, M Charbonneau, X Tang Scientific Reports 11 (1), 10956, 2021 | 26 | 2021 |