α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy? AP Kiely, YT Asi, E Kara, P Limousin, H Ling, P Lewis, C Proukakis, ... Acta neuropathologica 125, 753-769, 2013 | 518 | 2013 |
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear … MB Fares, N Ait-Bouziad, I Dikiy, MK Mbefo, A Jovičić, A Kiely, JL Holton, ... Human molecular genetics 23 (17), 4491-4509, 2014 | 268 | 2014 |
Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease C O'Neill, AP Kiely, MF Coakley, S Manning, CM Long-Smith Biochemical Society Transactions 40 (4), 721-727, 2012 | 163 | 2012 |
Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation AP Kiely, H Ling, YT Asi, E Kara, C Proukakis, AH Schapira, HR Morris, ... Molecular neurodegeneration 10, 1-17, 2015 | 117 | 2015 |
A 6.4 Mb duplication of the α-synuclein locus causing frontotemporal dementia and Parkinsonism: phenotype-genotype correlations E Kara, AP Kiely, C Proukakis, N Giffin, S Love, J Hehir, K Rantell, ... JAMA neurology 71 (9), 1162-1171, 2014 | 69 | 2014 |
Coenzyme Q10 levels are decreased in the cerebellum of multiple-system atrophy patients LV Schottlaender, C Bettencourt, AP Kiely, A Chalasani, V Neergheen, ... PloS one 11 (2), e0149557, 2016 | 63 | 2016 |
Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson’s disease SC Foti, I Hargreaves, S Carrington, AP Kiely, H Houlden, JL Holton Scientific Reports 9 (1), 6559, 2019 | 50 | 2019 |
Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 b-cell insulin secretion and signal transduction A Kiely, A Robinson, NH McClenaghan, PR Flatt, P Newsholme Journal of Endocrinology 202 (3), 365-373, 2009 | 35 | 2009 |
Neuropathological features of genetically confirmed DYT1 dystonia: investigating disease-specific inclusions R Paudel, A Kiely, A Li, T Lashley, R Bandopadhyay, J Hardy, HA Jinnah, ... Acta neuropathologica communications 2, 1-8, 2014 | 30 | 2014 |
Immunohistochemical and molecular investigations show alteration in the inflammatory profile of multiple system atrophy brain AP Kiely, CE Murray, SC Foti, BC Benson, R Courtney, C Strand, ... Journal of Neuropathology & Experimental Neurology 77 (7), 598-607, 2018 | 22 | 2018 |
Exploring the putative role of kallikrein‐6, calpain‐1 and cathepsin‐D in the proteolytic degradation of α‐synuclein in multiple system atrophy AP Kiely, JS Miners, R Courtney, C Strand, S Love, JL Holton Neuropathology and applied neurobiology 45 (4), 347-360, 2019 | 20 | 2019 |
Synucleinopathy with a G51D a-synuclein mutation: A neuropathological and genetic study AP Kiely, YT Asi, E Kara, P Limousin, H Ling, P Lewis, C Proukakis, ... Neuropathology and Applied Neurobiology 39, 39-40, 2013 | 4 | 2013 |
Coenzyme Q10 levels are reduced in the cerebellum of multiple system atrophy patients LV Schottlaender, C Bettencourt, A Kiely, A Chalasani, V Neergheen, ... Movement Disorders 30, S328-S329, 2015 | 2 | 2015 |
A decade of service development: audit of service users’ experience of a rural Psychiatry of Later Life (POLL) service M Usman, L Lally, S Costello, A Kiely, S Fahy Irish Journal of Medical Science (1971-), 1-8, 2022 | 1 | 2022 |
Mitochondrial dysfunction in multiple system atrophy SC Wauters, A Kiely, H Houlden, I Hargreaves, JL Holton NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 42, 37-38, 2016 | 1 | 2016 |
Microglial activation in multiple system atrophy AP Kiely, YT Asi, Z Ahmed, T Revesz, JL Holton NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 40, 37-37, 2014 | 1 | 2014 |
Defects in PINK1 are part of Alzheimer's disease pathogenesis and associate with alterations in the mitochondrial fission protein Drp1 AP Kiely, AM Moloney, C O'Flanagan, MF Coakley, C O'Neill MOVEMENT DISORDERS 27, S493-S494, 2012 | 1 | 2012 |
Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy S Foti, S Carrington, A Kiely, H Houlden, I Hargreaves, J Holton NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 44, 15-15, 2018 | | 2018 |
Genetic and proteomic profiling of sporadic and familial Alzheimer’s disease post-mortem brains CE Murray, P Gami-Patel, AP Kiely, J Holton 13th International Conference AD/PD, 2017 | | 2017 |
Distinct inflammatory profile in brains with multiple system atrophy A Kiely, CE Murray, Y Asi, Z Ahmed, T Lashley, T Revesz, J Holton Federation of European Neuroscience Societies (FENS), 2016 | | 2016 |