Helix-Turn-Helix Peptides That Form alpha-Helical Fibrils: Turn Sequences Drive Fibril Structure KL Lazar, H Miller-Auer, GS Getz, JPRO Orgel, SC Meredith Biochemistry 44, 12681-12689, 2005 | 75 | 2005 |
Substrate analogues to study cell-wall biosynthesis and its inhibition K Lazar, S Walker Current Opinion in Chemical Biology 6, 786-793, 2002 | 75 | 2002 |
Cold denaturation of monoclonal antibodies KL Lazar, TW Patapoff, VK Sharma MAbs 2, 42-52, 2010 | 61 | 2010 |
Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action HE Feinstein, SJ Benbow, NE LaPointe, N Patel, S Ramachandran, ... Journal of neurochemistry 137 (6), 939-954, 2016 | 44 | 2016 |
Hetero-oligomeric amyloid assembly and mechanism: Prion fragment PrP (106–126) catalyzes the islet amyloid polypeptide β-hairpin AI Ilitchev, MJ Giammona, C Olivas, SL Claud, KL Lazar Cantrell, C Wu, ... Journal of the American Chemical Society 140 (30), 9685-9695, 2018 | 37 | 2018 |
Catalytic prion-like cross-talk between a key Alzheimer’s disease tau-fragment R3 and the type 2 diabetes peptide IAPP S Arya, SL Claud, KL Cantrell, MT Bowers ACS Chemical Neuroscience 10 (11), 4757-4765, 2019 | 26 | 2019 |
Terminal capping of an amyloidogenic tau fragment modulates its fibrillation propensity S Arya, P Ganguly, A Arsiccio, SL Claud, B Trapp, GE Schonfeld, X Liu, ... The Journal of Physical Chemistry B 124 (40), 8772-8783, 2020 | 21 | 2020 |
Characterizing TDP-43307–319 Oligomeric Assembly: Mechanistic and Structural Implications Involved in the Etiology of Amyotrophic Lateral Sclerosis V Laos, TD Do, D Bishop, Y Jin, NM Marsh, B Quon, M Fetters, KL Cantrell, ... ACS Chemical Neuroscience 10 (9), 4112-4123, 2019 | 21 | 2019 |
Catalytic cross talk between key peptide fragments that couple Alzheimer’s disease with amyotrophic lateral sclerosis V Laos, D Bishop, P Ganguly, G Schonfeld, E Trapp, KL Cantrell, ... Journal of the American Chemical Society 143 (9), 3494-3502, 2021 | 12 | 2021 |
Cytotoxicity of α-Helical, Staphylococcus aureus PSMα3 Investigated by Post-Ion-Mobility Dissociation Mass Spectrometry ALH Gray, A Antevska, DS Oluwatoba, GE Schonfeld, KL Lazar Cantrell, ... Analytical Chemistry 92 (17), 11802-11808, 2020 | 10 | 2020 |
Modulating ALS-Related Amyloidogenic TDP-43307–319 Oligomeric Aggregates with Computationally Derived Therapeutic Molecules V Laos, D Bishop, CA Lang, NM Marsh, KL Cantrell, SK Buratto, AK Singh, ... Biochemistry 59 (4), 499-508, 2019 | 10 | 2019 |
Novel semi-synthetic method for generating full length beta-amyloid peptides JJ Bockhorn, KL Lazar, AJ Gasser, LM Luther, IM Qahwash, N Chopra, ... Biopolymers 94 (4), 511-520, 2010 | 10 | 2010 |
Elucidation of the Aggregation Pathways of Helix–Turn–Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation TD Do, A Chamas, X Zheng, A Barnes, D Chang, T Veldstra, H Takhar, ... Biochemistry 54 (26), 4050-4062, 2015 | 8 | 2015 |
Encapsulation and NMR of an Aggregating Peptide before Fibrillogenesis KL Lazar, JW Kurutz, R Tycko, SC Meredith Journal of the American Chemical Society 128, 16460-16461, 2006 | 7 | 2006 |
Optically detected magnetic resonance of alpha-deuterated 2-indanone KL Lazar, BE Greene, CS Stein, WP Johnson, PJ Choi, DF Marten, ... Journal of Luminescence 118, 21-32, 2006 | 3 | 2006 |
Investigating a Novel Neurodegenerative Disease Toxic Mechanism Involving Lipid Binding Specificity of Amyloid Oligomers SS Hirschbeck, ET Lindberg, JH Jang, MKR Jacob, KL Lazar Cantrell, ... ACS Chemical Neuroscience 15 (7), 1523-1532, 2024 | 1 | 2024 |
Deciphering the Molecular Dance: Exploring the Dynamic Interplay Between Mouse Insulin B9-23 Peptides and Their Variants A Antevska, KA Hess, CC Long, EJ Walker, JH Jang, RJ DeSoto, ... | | 2024 |
Computationally Designed Molecules Modulate ALS-Related Amyloidogenic TDP-43307–319 Aggregation X Liu, S Duan, Y Jin, E Walker, M Tsao, JH Jang, Z Chen, AK Singh, ... ACS Chemical Neuroscience 14 (24), 4395-4408, 2023 | | 2023 |
30-Second Biochemistry: The 50 vital processes in and around living organisms each explained in half a minute editor Contakes, Stephen | | 2021 |
Assembly of amyloid systems: The TDP-43 and SOD 1 proteins associated with Amyotrophic Lateral Sclerosis (ALS); key fragments and mutants M Bowers, V Laos, KL Cantrell, T Do ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |