Direct electron transfer between heme-containing enzymes and electrodes as basis for third generation biosensors L Gorton, A Lindgren, T Larsson, FD Munteanu, T Ruzgas, I Gazaryan Analytica Chimica Acta 400 (1-3), 91-108, 1999 | 667 | 1999 |
Comparison of physico-chemical characteristics of four laccases from different basidiomycetes SV Shleev, OV Morozova, OV Nikitina, ES Gorshina, TV Rusinova, ... Biochimie 86 (9-10), 693-703, 2004 | 279 | 2004 |
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms TW Faust, EH Chang, C Kowal, RA Berlin, IG Gazaryan, E Bertini, J Zhang, ... Proceedings of the National Academy of Sciences 107 (43), 18569-18574, 2010 | 230 | 2010 |
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase IG Gazaryan, BF Krasnikov, GA Ashby, RNF Thorneley, BS Kristal, ... Journal of Biological Chemistry 277 (12), 10064-10072, 2002 | 213 | 2002 |
Mechanism of indole-3-acetic acid oxidation by plant peroxidases: anaerobic stopped-flow spectrophotometric studies on horseradish and tobacco peroxidases IG Gazaryan, LM Lagrimini, GA Ashby, RNF THORNELEY Biochemical Journal 313 (3), 841-847, 1996 | 198 | 1996 |
Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced experimental … M Ahuja, NA Kaidery, L Yang, N Calingasan, N Smirnova, A Gaisin, ... Journal of Neuroscience 36 (23), 6332-6351, 2016 | 197 | 2016 |
Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease NA Kaidery, R Banerjee, L Yang, NA Smirnova, DM Hushpulian, KT Liby, ... Antioxidants & redox signaling 18 (2), 139-157, 2013 | 172 | 2013 |
Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition IG Gazaryan, IP Krasinskaya, BS Kristal, AM Brown Journal of Biological Chemistry 282 (33), 24373-24380, 2007 | 172 | 2007 |
Biosensors based on novel peroxidases with improved properties in direct and mediated electron transfer A Lindgren, T Ruzgas, L Gorton, E Csöregi, GB Ardila, IY Sakharov, ... Biosensors and Bioelectronics 15 (9-10), 491-497, 2000 | 170 | 2000 |
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway RE Haskew-Layton, JB Payappilly, NA Smirnova, TC Ma, KK Chan, ... Proceedings of the National Academy of Sciences 107 (40), 17385-17390, 2010 | 165 | 2010 |
Bioelectrochemical monitoring of phenols and aromatic amines in flow injection using novel plant peroxidases FD Munteanu, A Lindgren, J Emnéus, L Gorton, T Ruzgas, E Csöregi, ... Analytical Chemistry 70 (13), 2596-2600, 1998 | 165 | 1998 |
Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke RE Speer, SS Karuppagounder, M Basso, SF Sleiman, A Kumar, D Brand, ... Free Radical Biology and Medicine 62, 26-36, 2013 | 150 | 2013 |
Immobilization of peroxidase glycoprotein on gold electrodes modified with mixed epoxy-boronic acid monolayers JM Abad, M Vélez, C Santamaría, JM Guisán, PR Matheus, L Vázquez, ... Journal of the American Chemical Society 124 (43), 12845-12853, 2002 | 144 | 2002 |
Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators NA Smirnova, RE Haskew-Layton, M Basso, DM Hushpulian, ... Chemistry & biology 18 (6), 752-765, 2011 | 138 | 2011 |
Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models SS Karuppagounder, I Alim, SJ Khim, MW Bourassa, SF Sleiman, R John, ... Science translational medicine 8 (328), 328ra29-328ra29, 2016 | 130 | 2016 |
Oxidation of indole-3-acetic acid by dioxygen catalysed by plant peroxidases: specificity for the enzyme structure PA Savitsky, IG Gazaryan, VI Tishkov, LM Lagrimini, T Ruzgas, L Gorton Biochemical journal 340 (3), 579-583, 1999 | 129 | 1999 |
Purification and unusual kinetic properties of a tobacco anionic peroxidase IG Gazaryan, LM Lagrimini Phytochemistry 41 (4), 1029-1034, 1996 | 123 | 1996 |
Inhibition of 12/15‐lipoxygenase as therapeutic strategy to treat stroke K Yigitkanli, A Pekcec, H Karatas, S Pallast, E Mandeville, N Joshi, ... Annals of neurology 73 (1), 129-135, 2013 | 118 | 2013 |
Harnessing hypoxic adaptation to prevent, treat, and repair stroke RR Ratan, A Siddiq, N Smirnova, K Karpisheva, R Haskew-Layton, ... Journal of Molecular Medicine 85, 1331-1338, 2007 | 116 | 2007 |
Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation NA Smirnova, I Rakhman, N Moroz, M Basso, J Payappilly, S Kazakov, ... Chemistry & biology 17 (4), 380-391, 2010 | 105 | 2010 |