Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus T Manabe, DJ Wyllie, DJ Perkel, RA Nicoll Journal of neurophysiology 70 (4), 1451-1459, 1993 | 743 | 1993 |
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses S Papadia, FX Soriano, F Léveillé, MA Martel, KA Dakin, HH Hansen, ... Nature neuroscience 11 (4), 476-487, 2008 | 605 | 2008 |
Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles K Erreger, SM Dravid, TG Banke, DJA Wyllie, SF Traynelis The Journal of physiology 563 (2), 345-358, 2005 | 532 | 2005 |
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ... Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012 | 411 | 2012 |
Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors LC Anson, PE Chen, DJA Wyllie, D Colquhoun, R Schoepfer Journal of Neuroscience 18 (2), 581-589, 1998 | 297 | 1998 |
Single‐channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors DJA Wyllie, P Behe, D Colquhoun The Journal of physiology 510 (1), 1-18, 1998 | 293 | 1998 |
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ... Nature communications 8 (1), 15132, 2017 | 286 | 2017 |
Influence of GluN2 subunit identity on NMDA receptor function DJA Wyllie, MR Livesey, GE Hardingham Neuropharmacology 74, 4-17, 2013 | 284 | 2013 |
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals J Qiu, YW Tan, AM Hagenston, MA Martel, N Kneisel, PA Skehel, ... Nature communications 4 (1), 2034, 2013 | 277 | 2013 |
Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors P Béhé, P Stern, DJA Wyllie, M Nassar, R Schoepfer, D Colquhoun Proceedings of the Royal Society of London. Series B: Biological Sciences …, 1995 | 236 | 1995 |
Glutamate receptor gating K Erreger, PE Chen, DJA Wyllie, SF Traynelis Critical Reviews™ in Neurobiology 16 (3), 2004 | 230 | 2004 |
The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults MA Martel, TJ Ryan, KFS Bell, JH Fowler, A McMahon, B Al-Mubarak, ... Neuron 74 (3), 543-556, 2012 | 210 | 2012 |
Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling PE Chen, MT Geballe, PJ Stansfeld, AR Johnston, H Yuan, AL Jacob, ... Molecular pharmacology 67 (5), 1470-1484, 2005 | 206 | 2005 |
Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors K Erreger, MT Geballe, A Kristensen, PE Chen, KB Hansen, CJ Lee, ... Molecular pharmacology 72 (4), 907-920, 2007 | 202 | 2007 |
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ... Nature communications 9 (1), 347, 2018 | 199 | 2018 |
In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as … MA Martel, DJA Wyllie, GE Hardingham Neuroscience 158 (1), 334-343, 2009 | 191 | 2009 |
Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles EL Clayton, N Sue, KJ Smillie, T O'Leary, N Bache, G Cheung, AR Cole, ... Nature neuroscience 13 (7), 845-851, 2010 | 189 | 2010 |
Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand FX Soriano, MA Martel, S Papadia, A Vaslin, P Baxter, C Rickman, ... Journal of Neuroscience 28 (42), 10696-10710, 2008 | 185 | 2008 |
GRIN2A-related disorders: genotype and functional consequence predict phenotype V Strehlow, HO Heyne, DRM Vlaskamp, KFM Marwick, G Rudolf, ... Brain 142 (1), 80-92, 2019 | 184 | 2019 |
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2 KFS Bell, B Al-Mubarak, MA Martel, S McKay, N Wheelan, P Hasel, ... Nature communications 6 (1), 7066, 2015 | 182 | 2015 |