Hydroxyl alkyl ammonium ionic liquid assisted green and one-pot regioselective access to functionalized pyrazolodihydropyridine core and their pharmacological evaluation DM Patel, MG Sharma, RM Vala, I Lagunes, A Puerta, JM Padrón, ... Bioorganic chemistry 86, 137-150, 2019 | 64 | 2019 |
Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations I Lagunes, P Begines, A Silva, AR Galán, A Puerta, MX Fernandes, I Maya, ... European Journal of Medicinal Chemistry 179, 493-501, 2019 | 33 | 2019 |
A new oxadiazole-based topsentin derivative modulates cyclin-dependent kinase 1 expression and exerts cytotoxic effects on pancreatic cancer cells C Pecoraro, B Parrino, S Cascioferro, A Puerta, A Avan, GJ Peters, ... Molecules 27 (1), 19, 2021 | 32 | 2021 |
Synthesis and in vitro study of antiproliferative benzyloxy dihydropyrimidinones RM Vala, MG Sharma, DM Patel, A Puerta, JM Padron, V Ramkumar, ... Archiv der Pharmazie 354 (6), 2000466, 2021 | 28 | 2021 |
Synthesis of novel 1, 2, 3-triazole-dihydropyrimidinone hybrids using multicomponent 1, 3-dipolar cycloaddition (click)–Biginelli reactions: Anticancer activity EP Carreiro, AM Sena, A Puerta, JM Padron, AJ Burke Synlett 31 (06), 615-621, 2020 | 28 | 2020 |
Naphthol-derived Betti bases as potential SLC6A14 blockers A Puerta, AR Galán, R Abdilla, K Demanuele, MX Fernandes, G Bosica, ... Journal of Molecular and Clinical Medicine 2 (2), 35-40, 2019 | 22 | 2019 |
Microwave-assisted multicomponent synthesis of antiproliferative 2, 4-dimethoxy-tetrahydropyrimido [4, 5-b] quinolin-6 (7 H)-ones SG Patel, A González-Bakker, RM Vala, PJ Patel, A Puerta, A Malik, ... RSC advances 12 (47), 30404-30415, 2022 | 19 | 2022 |
2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases A Fuentes-Aguilar, P Merino-Montiel, S Montiel-Smith, S Meza-Reyes, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 168-177, 2022 | 15 | 2022 |
Study of the anticancer potential of Cd complexes of selenazoyl-hydrazones and their sulfur isosters SB Marković, N Maciejewska, M Olszewski, A Višnjevac, A Puerta, ... European journal of medicinal chemistry 238, 114449, 2022 | 14 | 2022 |
One-pot multicomponent green Hantzsch synthesis of 1, 2-dihydropyridine derivatives with antiproliferative activity G Bosica, K Demanuele, JM Padrón, A Puerta Beilstein Journal of Organic Chemistry 16 (1), 2862-2869, 2020 | 14 | 2020 |
Masked phenolic-selenium conjugates: Potent and selective antiproliferative agents overcoming P-gp resistance P Begines, L Sevilla-Horrillo, A Puerta, R Puckett, S Bayort, I Lagunes, ... Pharmaceuticals 13 (11), 358, 2020 | 13 | 2020 |
Squaramide-tethered sulfonamides and coumarins: Synthesis, inhibition of tumor-associated CAs IX and XII and docking simulations G Arrighi, A Puerta, A Petrini, FJ Hicke, A Nocentini, MX Fernandes, ... International Journal of Molecular Sciences 23 (14), 7685, 2022 | 11 | 2022 |
Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties MC Padilla-Pérez, EM Sánchez-Fernández, A González-Bakker, A Puerta, ... European journal of medicinal chemistry 255, 115390, 2023 | 10 | 2023 |
Synthesis and evaluation of pyrimidine steroids as antiproliferative agents A Cortés-Percino, JL Vega-Báez, A Romero-López, A Puerta, ... Molecules 24 (20), 3676, 2019 | 10 | 2019 |
A Focused Library of NO‐Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions M Ingold, L Colella, P Hernández, C Batthyány, D Tejedor, A Puerta, ... ChemMedChem 14 (18), 1669-1683, 2019 | 10 | 2019 |
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE) TCS Evangelista, Ó López, A Puerta, MX Fernandes, SB Ferreira, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2395-2402, 2022 | 8 | 2022 |
Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease M Velueta-Viveros, M Martinez-Bailen, A Puerta, LL Romero-Hernández, ... Bioorganic Chemistry 127, 105983, 2022 | 8 | 2022 |
Ugi adducts of isatin as promising antiproliferative agents with druglike properties P Brandão, A Puerta, JM Padrón, ML Kuznetsov, AJ Burke, M Pineiro Asian Journal of Organic Chemistry 10 (12), 3434-3455, 2021 | 8 | 2021 |
Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil. RE Barrientos, E Ibáñez, A Puerta, JM Padrón, A Paredes, F Cifuentes, ... Antioxidants 11 (12), 2313, 2022 | 7 | 2022 |
New pharmacological strategies against pancreatic adenocarcinoma: The multifunctional thiosemicarbazone FA4 DP Anobile, M Niso, A Puerta, SM Fraga Rodrigues, FS Abatematteo, ... Molecules 27 (5), 1682, 2022 | 7 | 2022 |