Modulation of ghrelin O-acyltransferase expression in pancreatic islets W An, Y Li, G Xu, J Zhao, X Xiang, L Ding, J Li, Y Guan, X Wang, C Tang, ... Cellular Physiology and Biochemistry 26 (4-5), 707-716, 2010 | 60 | 2010 |
Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to chemotherapy by abrogating the TopBP1/ATR-mediated DNA damage response L Ding, VS Madamsetty, S Kiers, O Alekhina, A Ugolkov, J Dube, Y Zhang, ... Clinical Cancer Research 25 (21), 6452-6462, 2019 | 59 | 2019 |
Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production H Chen, AK Victor, J Klein, KF Tacer, DJC Tai, C de Esch, A Nuttle, ... JCI insight 5 (17), 2020 | 56 | 2020 |
Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression Y Bi, VS Shirure, R Liu, C Cunningham, L Ding, JM Meacham, ... Integrative Biology 12 (9), 221-232, 2020 | 55 | 2020 |
Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice G Xu, Z Wang, Y Li, Z Li, H Tang, J Zhao, X Xiang, L Ding, L Ma, F Yuan, ... Diabetologia 55, 1813-1823, 2012 | 44 | 2012 |
Glycogen synthase kinase-3β: A novel therapeutic target for pancreatic cancer L Ding, DD Billadeau Expert opinion on therapeutic targets 24 (5), 417-426, 2020 | 39 | 2020 |
Glycogen synthase kinase‐3β ablation limits pancreatitis‐induced acinar‐to‐ductal metaplasia L Ding, GY Liou, DM Schmitt, P Storz, JS Zhang, DD Billadeau The Journal of pathology 243 (1), 65-77, 2017 | 39 | 2017 |
An FGFR/AKT/SOX2 signaling axis controls pancreatic cancer stemness MY Quan, Q Guo, J Liu, R Yang, J Bai, W Wang, Y Cai, R Han, YQ Lv, ... Frontiers in cell and developmental biology 8, 287, 2020 | 38 | 2020 |
Intestinal mTOR regulates GLP-1 production in mouse L cells G Xu, Z Li, L Ding, H Tang, S Guo, H Liang, H Wang, W Zhang Diabetologia 58, 1887-1897, 2015 | 34 | 2015 |
Regulation of gastric hormones by systemic rapamycin G Xu, Y Li, W An, J Zhao, X Xiang, L Ding, Z Li, Y Guan, X Wang, C Tang, ... Peptides 31 (12), 2185-2192, 2010 | 27 | 2010 |
WASH regulates glucose homeostasis by facilitating Glut2 receptor recycling in pancreatic β-cells L Ding, L Han, J Dube, DD Billadeau Diabetes 68 (2), 377-386, 2019 | 26 | 2019 |
TSC1-mTOR signaling determines the differentiation of islet cells L Ding, Y Yin, L Han, Y Li, J Zhao, W Zhang J Endocrinol 232 (1), 59-70, 2017 | 20 | 2017 |
Neurogenin 3–directed Cre deletion of Tsc1 gene causes pancreatic acinar carcinoma L Ding, L Han, Y Li, J Zhao, P He, W Zhang Neoplasia 16 (11), 909-917, 2014 | 18 | 2014 |
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy C Zuo, JM Baer, BL Knolhoff, JI Belle, X Liu, A Alarcon De La Lastra, C Fu, ... Journal of Experimental Medicine 220 (6), e20212062, 2023 | 15 | 2023 |
Arf GTPase activates the WAVE regulatory complex through a distinct binding site S Yang, Y Tang, Y Liu, AJ Brown, M Schaks, B Ding, DA Kramer, ... Science advances 8 (50), eadd1412, 2022 | 15 | 2022 |
Microfluidic organoid cultures derived from pancreatic cancer biopsies for personalized testing of chemotherapy and immunotherapy D Choi, AM Gonzalez‐Suarez, MG Dumbrava, M Medlyn, ... Advanced Science 11 (5), 2303088, 2024 | 10 | 2024 |
Comparison of intraoperative 3-dimensional fluoroscopy with standard computed tomography for stereotactic frame registration T Peng, DR Kramer, MB Lee, MF Barbaro, L Ding, CY Liu, S Kellis, B Lee Operative Neurosurgery 18 (6), 698-709, 2020 | 10 | 2020 |
Pancreas resident macrophage-induced fibrosis has divergent roles in pancreas inflammatory injury and PDAC JM Baer, C Zuo, LI Kang, A Alarcon de la Lastra, NC Borcherding, ... bioRxiv, 2022.02. 09.479745, 2022 | 7 | 2022 |
Nuclear GSK-3β and oncogenic KRas lead to the retention of pancreatic ductal progenitor cells phenotypically similar to those seen in IPMN L Ding, K Roeck, C Zhang, B Zidek, E Rodman, Y Hernandez-Barco, ... Frontiers in Cell and Developmental Biology 10, 853003, 2022 | 5 | 2022 |
Macrophage proliferation machinery leads to PDAC progression, but susceptibility to innate immunotherapy C Zuo, JM Baer, BL Knolhoff, JI Belle, X Liu, GD Hogg, C Fu, NL Kingston, ... bioRxiv, 2021.11. 08.467770, 2021 | 3 | 2021 |