Spiroindolone KAE609 for falciparum and vivax malaria NJ White, S Pukrittayakamee, AP Phyo, R Rueangweerayut, F Nosten, ... New England Journal of Medicine 371 (5), 403-410, 2014 | 275 | 2014 |
Role of polyanhydrides as localized drug carriers JP Jain, S Modi, AJ Domb, N Kumar Journal of Controlled Release 103 (3), 541-563, 2005 | 241 | 2005 |
Functionalized polymersomes for biomedical applications PV Pawar, SV Gohil, JP Jain, N Kumar Polymer Chemistry 4 (11), 3160-3176, 2013 | 140 | 2013 |
Self assembling polymers as polymersomes for drug delivery J Prakash Jain, W Yenet Ayen, N Kumar Current pharmaceutical design 17 (1), 65-79, 2011 | 92 | 2011 |
Polyanhydrides as localized drug delivery carrier: an update JP Jain, D Chitkara, N Kumar Expert opinion on drug delivery 5 (8), 889-907, 2008 | 92 | 2008 |
Fatty acid based biodegradable polymer JP Jain, M Sokolsky, N Kumar, AJ Domb Polymer Reviews 48 (1), 156-191, 2008 | 92 | 2008 |
Exploiting EPR in polymer drug conjugate delivery for tumor targeting S Modi, J Prakash Jain, AJ Domb, N Kumar Current pharmaceutical design 12 (36), 4785-4796, 2006 | 85 | 2006 |
Development of amphotericin B loaded polymersomes based on (PEG) 3-PLA co-polymers: Factors affecting size and in vitro evaluation JP Jain, N Kumar European journal of pharmaceutical sciences 40 (5), 456-465, 2010 | 82 | 2010 |
Self Assembly of Amphiphilic (PEG)3-PLA Copolymer as Polymersomes: Preparation, Characterization, and Their Evaluation As Drug Carrier JP Jain, N Kumar Biomacromolecules 11 (4), 1027-1035, 2010 | 77 | 2010 |
A first-in-human randomized, double-blind, placebo-controlled, single-and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess … FJ Leong, R Li, JP Jain, G Lefèvre, B Magnusson, TT Diagana, P Pertel Antimicrobial agents and chemotherapy 58 (10), 6209-6214, 2014 | 75 | 2014 |
Hydroxy fatty acid based polyanhydride as drug delivery system: Synthesis, characterization, in vitro degradation, drug release, and biocompatibility JP Jain, S Modi, N Kumar Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2008 | 58 | 2008 |
Biodegradable polymers in drug delivery JP Jain, W Yenet Ayen, AJ Domb, N Kumar Biodegradable polymers in clinical use and clinical development, 1-58, 2011 | 50 | 2011 |
Simultaneous determination of hydrazinocurcumin and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation R Rathore, JP Jain, A Srivastava, SM Jachak, N Kumar Journal of pharmaceutical and biomedical analysis 46 (2), 374-380, 2008 | 45 | 2008 |
Bioavailability of lumefantrine is significantly enhanced with a novel formulation approach, an outcome from a randomized, open-label pharmacokinetic study in healthy volunteers JP Jain, FJ Leong, L Chen, S Kalluri, V Koradia, DS Stein, MC Wolf, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00868-17, 2017 | 39 | 2017 |
Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria TT Hien, NJ White, NT Thuy-Nhien, NT Hoa, PD Thuan, J Tarning, ... Antimicrobial agents and chemotherapy 61 (2), 10.1128/aac. 01940-16, 2017 | 38 | 2017 |
Amphotericin-B-Loaded Polymersomes Formulation (PAMBO) Based on (PEG)3-PLA Copolymers: An in Vivo Evaluation in a Murine Model JP Jain, M Jatana, A Chakrabarti, N Kumar Molecular pharmaceutics 8 (1), 204-212, 2011 | 36 | 2011 |
KAE609 (cipargamin), a new spiroindolone agent for the treatment of malaria: evaluation of the absorption, distribution, metabolism, and excretion of a single oral 300-mg dose … SEW Huskey, C Zhu, A Fredenhagen, J Kühnöl, A Luneau, Z Jian, Z Yang, ... Drug Metabolism and disposition 44 (5), 672-682, 2016 | 35 | 2016 |
Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility S Modi, JP Jain, AJ Domb, N Kumar European journal of pharmaceutics and biopharmaceutics 64 (3), 277-286, 2006 | 34 | 2006 |
Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609 (cipargamin) and piperaquine DS Stein, JP Jain, M Kangas, G Lefèvre, S Machineni, P Griffin, J Lickliter Antimicrobial agents and chemotherapy 59 (6), 3493-3500, 2015 | 29 | 2015 |
Effect of PEG chain length and hydrophilic weight fraction on polymersomes prepared from branched (PEG)3‐PLA co‐polymers WY Ayen, B Chintankumar, JP Jain, N Kumar Polymers for Advanced Technologies 22 (1), 158-165, 2011 | 29 | 2011 |