Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model TE Sussan, S Gajghate, RK Thimmulappa, J Ma, JH Kim, K Sudini, ... PloS one 10 (2), e0116861, 2015 | 471 | 2015 |
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ... ACS chemical biology 11 (11), 3214-3225, 2016 | 448 | 2016 |
Hyperglycemia-driven neuroinflammation compromises BBB leading to memory loss in both diabetes mellitus (DM) type 1 and type 2 mouse models S Rom, V Zuluaga-Ramirez, S Gajghate, A Seliga, M Winfield, NA Heldt, ... Molecular neurobiology 56, 1883-1896, 2019 | 241 | 2019 |
miR-98 reduces endothelial dysfunction by protecting blood–brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model DL Bernstein, V Zuluaga-Ramirez, S Gajghate, NL Reichenbach, ... Journal of Cerebral Blood Flow & Metabolism 40 (10), 1953-1965, 2020 | 99 | 2020 |
Cited2 modulates hypoxia‐inducible factor–dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc A Agrawal, S Gajghate, H Smith, DG Anderson, TJ Albert, IM Shapiro, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 94 | 2008 |
PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc CC Cheng, Y Uchiyama, A Hiyama, S Gajghate, IM Shapiro, MV Risbud Journal of cellular physiology 221 (3), 668-676, 2009 | 93 | 2009 |
Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function TE Sussan, S Gajghate, S Chatterjee, P Mandke, S McCormick, K Sudini, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (1 …, 2015 | 84 | 2015 |
Antiinflammatory role of MUC1 mucin during infection with nontypeable Haemophilus influenzae. KKC Kyo Y1, Kato K, Park YS, Gajghate S, Umehara T, Lillehoj EP, Suzaki H Am J Respir Cell Mol Biol 46 (2), 149-56, 2012 | 83 | 2012 |
Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles S Rom, NA Heldt, S Gajghate, A Seliga, NL Reichenbach, Y Persidsky Scientific reports 10 (1), 7274, 2020 | 80 | 2020 |
BMP‐2 and TGF‐β stimulate expression of β1, 3‐glucuronosyl transferase 1 (GlcAT‐1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: Role of MAPKs A Hiyama, SS Gogate, S Gajghate, J Mochida, IM Shapiro, MV Risbud Journal of Bone and Mineral Research 25 (5), 1179-1190, 2010 | 78 | 2010 |
Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc S Gajghate, A Hiyama, M Shah, D Sakai, DG Anderson, IM Shapiro, ... Journal of Bone and Mineral Research 24 (6), 992-1001, 2009 | 69 | 2009 |
Activation of GPR55 induces neuroprotection of hippocampal neurogenesis and immune responses of neural stem cells following chronic, systemic inflammation JD Hill, V Zuluaga-Ramirez, S Gajghate, M Winfield, U Sriram, S Rom, ... Brain, behavior, and immunity 76, 165-181, 2019 | 60 | 2019 |
Activation of TonEBP by calcium controls β1, 3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc A Hiyama, S Gajghate, D Sakai, J Mochida, IM Shapiro, MV Risbud Journal of Biological Chemistry 284 (15), 9824-9834, 2009 | 59 | 2009 |
Electronic cigarette exposure disrupts blood-brain barrier integrity and promotes neuroinflammation NA Heldt, A Seliga, M Winfield, S Gajghate, N Reichenbach, X Yu, S Rom, ... Brain, behavior, and immunity 88, 363-380, 2020 | 44 | 2020 |
PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier S Rom, V Zuluaga-Ramirez, NL Reichenbach, H Dykstra, S Gajghate, ... Journal of Neuroinflammation 13, 1-16, 2016 | 44 | 2016 |
Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis JD Hill, V Zuluaga‐Ramirez, S Gajghate, M Winfield, Y Persidsky British journal of pharmacology 175 (16), 3407-3421, 2018 | 43 | 2018 |
Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation S Rom, V Zuluaga-Ramirez, NL Reichenbach, MA Erickson, M Winfield, ... Journal of Neuroinflammation 15, 1-10, 2018 | 41 | 2018 |
SMAD3 functions as a transcriptional repressor of acid‐sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc Y Uchiyama, A Guttapalli, S Gajghate, J Mochida, IM Shapiro, MV Risbud Journal of Bone and Mineral Research 23 (10), 1619-1628, 2008 | 39 | 2008 |
let-7g counteracts endothelial dysfunction and ameliorating neurological functions in mouse ischemia/reperfusion stroke model DL Bernstein, S Gajghate, NL Reichenbach, M Winfield, Y Persidsky, ... Brain, behavior, and immunity 87, 543-555, 2020 | 25 | 2020 |
Chronic intrahippocampal infusion of HIV-1 neurotoxic proteins: a novel mouse model of HIV-1 associated inflammation and neural stem cell dysfunction JD Hill, V Zuluaga-Ramirez, S Gajghate, M Winfield, Y Persidsky Journal of NeuroImmune Pharmacology 14, 375-382, 2019 | 9 | 2019 |