BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression AM Roccaro, A Sacco, P Maiso, AK Azab, YT Tai, M Reagan, F Azab, ... The Journal of clinical investigation 123 (4), 1542-1555, 2013 | 847 | 2013 |
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy AK Azab, JM Runnels, C Pitsillides, AS Moreau, F Azab, X Leleu, X Jia, ... Blood, The Journal of the American Society of Hematology 113 (18), 4341-4351, 2009 | 485 | 2009 |
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma AM Roccaro, A Sacco, B Thompson, X Leleu, AK Azab, F Azab, J Runnels, ... Blood, The Journal of the American Society of Hematology 113 (26), 6669-6680, 2009 | 396 | 2009 |
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features AK Azab, J Hu, P Quang, F Azab, C Pitsillides, R Awwad, B Thompson, ... Blood, The Journal of the American Society of Hematology 119 (24), 5782-5794, 2012 | 354 | 2012 |
Engineered nanomedicine for myeloma and bone microenvironment targeting A Swami, MR Reagan, P Basto, Y Mishima, N Kamaly, S Glavey, S Zhang, ... Proceedings of the National Academy of Sciences 111 (28), 10287-10292, 2014 | 284 | 2014 |
Prognostic role of circulating exosomal miRNAs in multiple myeloma S Manier, CJ Liu, H Avet-Loiseau, J Park, J Shi, F Campigotto, KZ Salem, ... Blood, The Journal of the American Society of Hematology 129 (17), 2429-2436, 2017 | 266 | 2017 |
Metabolic signature identifies novel targets for drug resistance in multiple myeloma P Maiso, D Huynh, M Moschetta, A Sacco, Y Aljawai, Y Mishima, ... Cancer research 75 (10), 2071-2082, 2015 | 246 | 2015 |
C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma AM Roccaro, A Sacco, C Jimenez, P Maiso, M Moschetta, Y Mishima, ... Blood, The Journal of the American Society of Hematology 123 (26), 4120-4131, 2014 | 228 | 2014 |
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenstrom macroglobulinemia treated with nucleoside analogs X Leleu, J Soumerai, A Roccaro, E Hatjiharissi, ZR Hunter, R Manning, ... Journal of Clinical Oncology 27 (2), 250-255, 2009 | 194 | 2009 |
Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-κB signaling pathways in Waldenstrom's macroglobulinemia E Braggio, JJ Keats, X Leleu, S Van Wier, VH Jimenez-Zepeda, R Valdez, ... Cancer research 69 (8), 3579-3588, 2009 | 190 | 2009 |
LNA-mediated anti–miR-155 silencing in low-grade B-cell lymphomas Y Zhang, AM Roccaro, C Rombaoa, L Flores, S Obad, SM Fernandes, ... Blood, The Journal of the American Society of Hematology 120 (8), 1678-1686, 2012 | 182 | 2012 |
SDF-1 inhibition targets the bone marrow niche for cancer therapy AM Roccaro, A Sacco, WG Purschke, M Moschetta, K Buchner, C Maasch, ... Cell reports 9 (1), 118-128, 2014 | 161 | 2014 |
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition M Cea, A Cagnetta, M Fulciniti, YT Tai, T Hideshima, D Chauhan, ... Blood, The Journal of the American Society of Hematology 120 (17), 3519-3529, 2012 | 157 | 2012 |
SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia HT Ngo, X Leleu, J Lee, X Jia, M Melhem, J Runnels, AS Moreau, ... Blood, The Journal of the American Society of Hematology 112 (1), 150-158, 2008 | 151 | 2008 |
Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenström's macroglobulinemia IM Ghobrial, A Roccaro, F Hong, E Weller, N Rubin, R Leduc, M Rourke, ... Clinical Cancer Research 16 (3), 1033-1041, 2010 | 142 | 2010 |
RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma AK Azab, F Azab, S Blotta, CM Pitsillides, B Thompson, JM Runnels, ... Blood, The Journal of the American Society of Hematology 114 (3), 619-629, 2009 | 140 | 2009 |
Targeting NF-κB in Waldenstrom macroglobulinemia X Leleu, J Eeckhoute, X Jia, AM Roccaro, AS Moreau, M Farag, A Sacco, ... Blood, The Journal of the American Society of Hematology 111 (10), 5068-5077, 2008 | 140 | 2008 |
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal-transition-like transcriptional activation AM Roccaro, Y Mishima, A Sacco, M Moschetta, YT Tai, J Shi, Y Zhang, ... Cell reports 12 (4), 622-635, 2015 | 138 | 2015 |
microRNA-dependent modulation of histone acetylation in Waldenström macroglobulinemia AM Roccaro, A Sacco, X Jia, AK Azab, P Maiso, HT Ngo, F Azab, ... Blood, The Journal of the American Society of Hematology 116 (9), 1506-1514, 2010 | 135 | 2010 |
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment AK Azab, P Quang, F Azab, C Pitsillides, B Thompson, T Chonghaile, ... Blood, The Journal of the American Society of Hematology 119 (6), 1468-1478, 2012 | 133 | 2012 |