Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population H Korkaya, G Kim, A Davis, F Malik, NL Henry, S Ithimakin, AA Quraishi, ... Molecular cell 47 (4), 570-584, 2012 | 581 | 2012 |
Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells JP Burnett, G Lim, Y Li, RB Shah, R Lim, HJ Paholak, SP McDermott, ... Cancer Letters 394, 52-64, 2017 | 132 | 2017 |
Highly crystallized iron oxide nanoparticles as effective and biodegradable mediators for photothermal cancer therapy H Chen, J Burnett, F Zhang, J Zhang, H Paholak, D Sun Journal of Materials Chemistry B 2 (7), 757-765, 2014 | 130 | 2014 |
Applications of human pharmacokinetic prediction in first-in-human dose estimation P Zou, Y Yu, N Zheng, Y Yang, HJ Paholak, LX Yu, D Sun The AAPS journal 14, 262-281, 2012 | 120 | 2012 |
‘Living’PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities H Chen, H Paholak, M Ito, K Sansanaphongpricha, W Qian, Y Che, D Sun Nanotechnology 24 (35), 355101, 2013 | 83 | 2013 |
Noninvasive Fluorescence Resonance Energy Transfer Imaging of in Vivo Premature Drug Release from Polymeric Nanoparticles P Zou, H Chen, HJ Paholak, D Sun Molecular pharmaceutics 10 (11), 4185-4194, 2013 | 79 | 2013 |
Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy HJ Paholak, NO Stevers, H Chen, JP Burnett, M He, H Korkaya, ... Biomaterials 104, 145-157, 2016 | 52 | 2016 |
Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy H Chen, X Luan, HJ Paholak, JP Burnett, NO Stevers, ... Nanomedicine 15 (1), 77-92, 2020 | 43 | 2020 |
Intracellular dissociation of a polymer coating from nanoparticles H Chen, P Zou, J Connarn, H Paholak, D Sun Nano Research 5, 815-825, 2012 | 27 | 2012 |
Thiol-reactive amphiphilic block copolymer for coating gold nanoparticles with neutral and functionable surfaces H Chen, H Zou, HJ Paholak, M Ito, W Qian, Y Che, D Sun Polymer chemistry 5 (8), 2768-2773, 2014 | 21 | 2014 |
Facile fabrication of near-infrared-resonant and magnetic resonance imaging-capable nanomediators for photothermal therapy H Chen, X Ren, HJ Paholak, J Burnett, F Ni, X Fang, D Sun ACS applied materials & interfaces 7 (23), 12814-12823, 2015 | 20 | 2015 |
Self-assembled Au@ Fe core/satellite magnetic nanoparticles for versatile biomolecule functionalization H Chen, H Hu, C Tao, RM Clauson, I Moncion, X Luan, S Hwang, ... ACS applied materials & interfaces 11 (27), 23858-23869, 2019 | 16 | 2019 |
Burst release of lipophilic drugs from poly (ethylene oxide)-B-polystyrene micelles is not caused by micelle disassembly P Zou, HW Chen, HJ Paholak Journal of tumor 1 (2), 2013 | 8 | 2013 |
Conjugated gold nanoparticles D Sun, H Chen, W Qian, Y Che, M Ito, H Paholak, K Sansanaphongpricha US Patent 9,234,078, 2016 | 4 | 2016 |
Combination of docetaxel with sulforaphane synergistically inhibits triple negative breast cancer and cancer stem cells JP Burnett, RB Shah, HJ Paholak, SP McDermott, Y Tsume, MW Wicha, ... Cancer Research 75 (15_Supplement), 4076-4076, 2015 | 3 | 2015 |
'Living'PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities C Hongwei, H Paholak, K Sansanaphongpricha, D Sun, M Ito, Q Wei, ... Nanotechnology (Print) 24, 2013 | 3 | 2013 |
Conjugated gold nanoparticles D Sun, H Chen, W Qian, Y Che, M Ito, H Paholak, K Sansanaphongpricha US Patent 9,587,071, 2017 | 2 | 2017 |
Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem JP Burnett, G Lim, Y Li, RB Shah, R Lim, HJ Paholak, SP McDermott, ... | 2 | |
Epithelial-like breast cancer stem cells are preferentially sensitive to nanoparticle-mediated hyperthermia HJ Paholak, NO Stevers, JP Burnett, H Chen, SP McDermott, M He, ... Cancer Research 75 (15_Supplement), 4239-4239, 2015 | 1 | 2015 |
Nanoparticle Design and Novel Approaches to Enhance Photothermal Cancer Therapy. HJS Paholak | 1 | 2015 |