Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis B Mittra, A Saha, A Roy Chowdhury, C Pal, S Mandal, S Mukhopadhyay, ... Molecular Medicine 6, 527-541, 2000 | 332 | 2000 |
Associations between metabolites of aromatic compounds in bile and the occurrence of hepatic lesions in English sole (Parophrys vetulus) from Puget Sound … MM Krahn, LD Rhodes, MS Myers, LK Moore, WD MacLeod, DC Malins Archives of Environmental Contamination and Toxicology 15, 61-67, 1986 | 307 | 1986 |
Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani N Sen, BB Das, A Ganguly, T Mukherjee, G Tripathi, S Bandyopadhyay, ... Cell Death & Differentiation 11 (8), 924-936, 2004 | 299 | 2004 |
Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I AR Chowdhury, S Sharma, S Mandal, A Goswami, S Mukhopadhyay, ... Biochemical Journal 366 (2), 653-661, 2002 | 260 | 2002 |
PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage BB Das, SN Huang, J Murai, I Rehman, JC Ame, S Sengupta, SK Das, ... Nucleic acids research 42 (7), 4435-4449, 2014 | 232 | 2014 |
Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3, 3′-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular … A Roy, A Ganguly, S BoseDasgupta, BB Das, C Pal, P Jaisankar, ... Molecular Pharmacology 74 (5), 1292-1307, 2008 | 185 | 2008 |
Betulinic acid, a potent inhibitor of eukaryotic topoisomerase I: identification of the inhibitory step, the major functional group responsible and development of more potent … AR Chowdhury, S Mandal, B Mittra, S Sharma, S Mukhopadhyay, ... Medical Science Monitor 8 (7), BR254-BR260, 2002 | 181 | 2002 |
Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani R Das, A Roy, N Dutta, HK Majumder Apoptosis 13, 867-882, 2008 | 178 | 2008 |
Diospyrin, a bisnaphthoquinone: a novel inhibitor of type I DNA topoisomerase of Leishmania donovani S Ray, B Hazra, B Mittra, A Das, HK Majumder Molecular pharmacology 54 (6), 994-999, 1998 | 167 | 1998 |
Camptothecin-induced imbalance in intracellular cation homeostasis regulates programmed cell death in unicellular hemoflagellate Leishmania donovani N Sen, BB Das, A Ganguly, T Mukherjee, S Bandyopadhyay, ... Journal of Biological Chemistry 279 (50), 52366-52375, 2004 | 158 | 2004 |
Amarogentin, a Naturally Occurring Secoiridoid Glycoside and a Newly Recognized Inhibitor of Topoisomerase I from Leishmania donovani S Ray, HK Majumder, AK Chakravarty, S Mukhopadhyay, RR Gil, ... Journal of natural products 59 (1), 27-29, 1996 | 158 | 1996 |
Mode of action of pentavalent antimonials: Specific inhibition of type I DNA topoisomerase of Leishmaniadonovani AK Chakraborty, HK Majumder Biochemical and biophysical research communications 152 (2), 605-611, 1988 | 136 | 1988 |
Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex N Sen, B Banerjee, BB Das, A Ganguly, T Sen, S Pramanik, ... Cell Death & Differentiation 14 (2), 358-367, 2007 | 131 | 2007 |
Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species–mediated apoptotic topoisomerase I–DNA cleavable complex formation in prostate cancer … A Ganguly, B Das, A Roy, N Sen, SB Dasgupta, S Mukhopadhayay, ... Cancer research 67 (24), 11848-11858, 2007 | 117 | 2007 |
Dihydrobetulinic Acid Induces Apoptosis in Leishmania donovani by Targeting DNA Topoisomerase I and II: Implications in Antileishmanial Therapy A Roy Chowdhury, S Mandal, A Goswami, M Ghosh, L Mandal, ... Molecular Medicine 9, 26-36, 2003 | 116 | 2003 |
Topoisomerases of kinetoplastid parasites as potential chemotherapeutic targets A Das, A Dasgupta, T Sengupta, HK Majumder TRENDS in Parasitology 20 (8), 381-387, 2004 | 98 | 2004 |
Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani BB Das, N Sen, A Ganguly, HK Majumder FEBS letters 565 (1-3), 81-88, 2004 | 94 | 2004 |
Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones … BB Das, N Sen, A Roy, SB Dasgupta, A Ganguly, BC Mohanta, B Dinda, ... Nucleic acids research 34 (4), 1121-1132, 2006 | 91 | 2006 |
16α‐Hydroxycleroda‐3,13 (14)Z‐dien‐15,16‐olide from Polyalthia longifolia: a safe and orally active antileishmanial agent P Misra, KV Sashidhara, SP Singh, A Kumar, R Gupta, SS Chaudhaery, ... British journal of pharmacology 159 (5), 1143-1150, 2010 | 89 | 2010 |
Homologous 3′-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei HK Majumder, JC Boothroyd, H Weber Nucleic acids research 9 (18), 4745-4753, 1981 | 85 | 1981 |