Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13) F Curnis, A Sacchi, L Borgna, F Magni, A Gasparri, A Corti Nature biotechnology 18 (11), 1185-1190, 2000 | 545 | 2000 |
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells F Curnis, G Arrigoni, A Sacchi, L Fischetti, W Arap, R Pasqualini, A Corti Cancer research 62 (3), 867-874, 2002 | 381 | 2002 |
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration F Curnis, A Sacchi, A Corti The Journal of clinical investigation 110 (4), 475-482, 2002 | 335 | 2002 |
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif G Colombo, F Curnis, GMS De Mori, A Gasparri, C Longoni, A Sacchi, ... Journal of Biological Chemistry 277 (49), 47891-47897, 2002 | 253 | 2002 |
Spontaneous formation of L-isoaspartate and gain of function in fibronectin F Curnis, R Longhi, L Crippa, A Cattaneo, E Dondossola, A Bachi, A Corti Journal of Biological Chemistry 281 (47), 36466-36476, 2006 | 231 | 2006 |
Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function M Pieroni, A Corti, B Tota, F Curnis, T Angelone, B Colombo, MC Cerra, ... European heart journal 28 (9), 1117-1127, 2007 | 225 | 2007 |
The neovasculature homing motif NGR: more than meets the eye A Corti, F Curnis, W Arap, R Pasqualini Blood, The Journal of the American Society of Hematology 112 (7), 2628-2635, 2008 | 222 | 2008 |
Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-α A Sacchi, A Gasparri, C Gallo-Stampino, S Toma, F Curnis, A Corti Clinical Cancer Research 12 (1), 175-182, 2006 | 191 | 2006 |
Coupling Tumor Necrosis Factor-α with αV Integrin Ligands Improves Its Antineoplastic Activity F Curnis, A Gasparri, A Sacchi, R Longhi, A Corti Cancer research 64 (2), 565-571, 2004 | 182 | 2004 |
Targeting TNF-α to neoangiogenic vessels enhances lymphocyte infiltration in tumors and increases the therapeutic potential of immunotherapy A Calcinotto, M Grioni, E Jachetti, F Curnis, A Mondino, G Parmiani, ... The Journal of Immunology 188 (6), 2687-2694, 2012 | 150 | 2012 |
Roles of tumor necrosis factor p55 and p75 receptors in TNF-α-induced vascular permeability E Ferrero, MR Zocchi, E Magni, MC Panzeri, F Curnis, C Rugarli, ... American Journal of Physiology-Cell Physiology 281 (4), C1173-C1179, 2001 | 145 | 2001 |
Chromogranin A protects vessels against tumor necrosis factor α‐induced vascular leakage E Ferrero, S Scabini, E Magni, C Foglieni, D Belloni, B Colombo, F Curnis, ... The FASEB journal 18 (3), 554-556, 2004 | 142 | 2004 |
Targeted drug delivery and penetration into solid tumors A Corti, F Pastorino, F Curnis, W Arap, M Ponzoni, R Pasqualini Medicinal research reviews 32 (5), 1078-1091, 2012 | 135 | 2012 |
Targeted delivery of IFNγ to tumor vessels uncouples antitumor from counterregulatory mechanisms F Curnis, A Gasparri, A Sacchi, A Cattaneo, F Magni, A Corti Cancer research 65 (7), 2906-2913, 2005 | 120 | 2005 |
Structural basis for the interaction of isoDGR with the RGD-binding site of αvβ3 integrin A Spitaleri, S Mari, F Curnis, C Traversari, R Longhi, C Bordignon, A Corti, ... Journal of Biological Chemistry 283 (28), 19757-19768, 2008 | 117 | 2008 |
Isoaspartate-dependent molecular switches for integrin–ligand recognition A Corti, F Curnis Journal of cell science 124 (4), 515-522, 2011 | 105 | 2011 |
Structure-activity relationships of chromogranin A in cell adhesion: identification of an adhesion site for fibroblasts and smooth muscle cells S Ratti, F Curnis, R Longhi, B Colombo, A Gasparri, F Magni, E Manera, ... Journal of Biological Chemistry 275 (38), 29257-29263, 2000 | 105 | 2000 |
Tumor pretargeting with avidin improves the therapeutic index of biotinylated tumor necrosis factor α in mouse models A Gasparri, M Moro, F Curnis, A Sacchi, S Pagano, F Veglia, G Casorati, ... Cancer research 59 (12), 2917-2923, 1999 | 104 | 1999 |
Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching F Curnis, A Cattaneo, R Longhi, A Sacchi, AM Gasparri, F Pastorino, ... Journal of biological chemistry 285 (12), 9114-9123, 2010 | 94 | 2010 |
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma M Loi, S Marchiò, P Becherini, D Di Paolo, M Soster, F Curnis, C Brignole, ... Journal of controlled release 145 (1), 66-73, 2010 | 91 | 2010 |