| Glucocorticoid receptor-dependent gene regulatory networks P Phuc Le, JR Friedman, J Schug, JE Brestelli, JB Parker, IM Bochkis, ... PLoS genetics 1 (2), e16, 2005 | 288 | 2005 |
| Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress IM Bochkis, NE Rubins, P White, EE Furth, JR Friedman, KH Kaestner Nature medicine 14 (8), 828-836, 2008 | 206 | 2008 |
| Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver IM Bochkis, D Przybylski, J Chen, A Regev Cell reports 9 (3), 996-1006, 2014 | 80 | 2014 |
| Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2 IM Bochkis, J Schug, DZ Ye, S Kurinna, SA Stratton, MC Barton, ... PLoS genetics 8 (6), e1002770, 2012 | 54 | 2012 |
| Impaired male fertility and atrophy of seminiferous tubules caused by haploinsufficiency for Foxa3 R Behr, SD Sackett, IM Bochkis, PP Le, KH Kaestner Developmental biology 306 (2), 636-645, 2007 | 48 | 2007 |
| Foxa2-dependent hepatic gene regulatory networks depend on physiological state IM Bochkis, J Schug, NE Rubins, AR Chopra, BW O'Malley, KH Kaestner Physiological genomics, 2009 | 32 | 2009 |
| Hdac3, Setdb1, and Kap1 mark H3K9me3/H3K14ac bivalent regions in young and aged liver AJ Price, MC Manjegowda, J Kain, S Anandh, IM Bochkis Aging Cell 19 (2), e13092, 2020 | 29 | 2020 |
| Bile acid-induced inflammatory signaling in mice lacking Foxa2 in the liver leads to activation of mTOR and age-onset obesity IM Bochkis, S Shin, KH Kaestner Molecular metabolism 2 (4), 447-456, 2013 | 29 | 2013 |
| Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver H Whitton, LN Singh, MA Patrick, AJ Price, FG Osorio, C López‐Otín, ... Aging Cell 17 (3), e12742, 2018 | 28 | 2018 |
| Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis CM Upchurch, S Yeudall, CM Pavelec, D Merk, J Greulich, ... Science Advances 8 (28), eabn0050, 2022 | 16 | 2022 |
| Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα J Kain, X Wei, NA Reddy, AJ Price, C Woods, IM Bochkis Molecular Metabolism 53, 101291, 2021 | 14 | 2021 |
| Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease X Wei, MA Murphy, NA Reddy, Y Hao, TG Eggertsen, JJ Saucerman, ... Genome Research 32 (11-12), 1981-1992, 2022 | 6 | 2022 |
| Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation ME Granade, SR Hargett, DS Lank, MC Lemke, MA Luse, BE Isakson, ... Molecular Metabolism 63, 101543, 2022 | 3 | 2022 |
| Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR Y Hao, L Han, A Wu, IM Bochkis Cellular and Molecular Gastroenterology and Hepatology 17 (2), 237-249, 2024 | 1 | 2024 |
| Reduced ZMPSTE24 expression leads to prelamin accumulation and development of steatosis in MASLD patients. A Wu, JD Schinderle, I Bochkis bioRxiv, 2024.05. 16.594546, 2024 | | 2024 |
| OR33-06 Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes In Ligand-dependent Activation Of FXR Y Hao, L Han, C Wu, I Bochkis Journal of the Endocrine Society 7 (Supplement_1), bvad114. 1774, 2023 | | 2023 |
| Pioneer factor Foxa2 mediates chromatin conformation changes in ligand-dependent activation of nuclear receptor FXR Y Hao, L Han, A Wu, IM Bochkis bioRxiv, 2023.03. 06.531297, 2023 | | 2023 |
| AAV8-mediated expression of scFv-E06 to target oxidized phosphatidylcholines protects against hepatic fibrosis C Upchurch, S Yeudall, C Pavelec, D Merk, J Greulich, M Manjegowda, ... Free Radical Biology and Medicine 192, 93, 2022 | | 2022 |
| Virus‐induced Hepatic Expression of an Oxidized Phospholipid‐binding Antibody Fragment Prevents Initiation of Hepatic Steatosis and Progression to Fibrosis CM Upchurch, S Yeudall, CM Pavelec, M Manjegowda, IM Bochkis, ... The FASEB Journal 36, 2022 | | 2022 |
| Pioneer factor Foxa2 enables ligand-dependent activation of LXRα J Kain, X Wei, AJ Price, C Woods, IM Bochkis bioRxiv, 2020.04. 10.036061, 2020 | | 2020 |
