Alternative splicing directs the expression of two D2 dopamine receptor isoforms B Giros, P Sokoloff, MP Martres, JF Riou, LJ Emorine, JC Schwartz Nature 342 (6252), 923-926, 1989 | 905 | 1989 |
Targeting telomeres and telomerase A De Cian, L Lacroix, C Douarre, N Temime-Smaali, C Trentesaux, ... Biochimie 90 (1), 131-155, 2008 | 685 | 2008 |
Natural and pharmacological regulation of telomerase JL Mergny, JF Riou, P Mailliet, MP Teulade-Fichou, E Gilson Nucleic Acids Research 30 (4), 839-865, 2002 | 518 | 2002 |
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands JF Riou, L Guittat, P Mailliet, A Laoui, E Renou, O Petitgenet, ... Proceedings of the National Academy of Sciences 99 (5), 2672-2677, 2002 | 503 | 2002 |
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres R Rodriguez, S Müller, JA Yeoman, C Trentesaux, JF Riou, ... Journal of the American Chemical Society 130 (47), 15758-15759, 2008 | 487 | 2008 |
Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I F Rossi, E Labourier, T Forné, G Divita, J Derancourt, JF Riou, E Antoine, ... Nature 381 (6577), 80-82, 1996 | 406 | 1996 |
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay JL Mergny, L Lacroix, MP Teulade-Fichou, C Hounsou, L Guittat, ... Proceedings of the National Academy of Sciences 98 (6), 3062-3067, 2001 | 403 | 2001 |
The Bloom's syndrome gene product interacts with topoisomerase III L Wu, SL Davies, PS North, H Goulaouic, JF Riou, H Turley, KC Gatter, ... Journal of Biological Chemistry 275 (13), 9636-9644, 2000 | 365 | 2000 |
Preferential binding of a G-quadruplex ligand to human chromosome ends C Granotier, G Pennarun, L Riou, F Hoffschir, LR Gauthier, A De Cian, ... Nucleic acids research 33 (13), 4182-4190, 2005 | 327 | 2005 |
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands G Pennarun, C Granotier, LR Gauthier, D Gomez, F Hoffschir, E Mandine, ... Oncogene 24 (18), 2917-2928, 2005 | 308 | 2005 |
Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes F Koeppel, JF Riou, A Laoui, P Mailliet, PB Arimondo, D Labit, ... Nucleic acids research 29 (5), 1087-1096, 2001 | 299 | 2001 |
Telomerase downregulation induced by the G‐quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing D Gomez, T Lemarteleur, L Lacroix, P Mailliet, JL Mergny, JF Riou Nucleic acids research 32 (1), 371-379, 2004 | 293 | 2004 |
Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase T Lemarteleur, D Gomez, R Paterski, E Mandine, P Mailliet, JF Riou Biochemical and biophysical research communications 323 (3), 802-808, 2004 | 269 | 2004 |
Preclinical evaluation of docetaxel (Taxotere). F Lavelle, MC Bissery, C Combeau, JF Riou, P Vrignaud, S Andre Seminars in oncology 22 (2 Suppl 4), 3-16, 1995 | 252 | 1995 |
The G-quadruplex Ligand Telomestatin Inhibits POT1 Binding to Telomeric Sequences In vitro and Induces GFP-POT1 Dissociation from Telomeres in Human Cells D Gomez, MF O'Donohue, T Wenner, C Douarre, J Macadré, P Koebel, ... Cancer research 66 (14), 6908-6912, 2006 | 251 | 2006 |
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells D Gomez, T Wenner, B Brassart, C Douarre, MF O'Donohue, V El Khoury, ... Journal of Biological Chemistry 281 (50), 38721-38729, 2006 | 247 | 2006 |
Preclinical antitumor activity of cabazitaxel, a semisynthetic taxane active in taxane-resistant tumors P Vrignaud, D Sémiond, P Lejeune, H Bouchard, L Calvet, C Combeau, ... Clinical Cancer Research 19 (11), 2973-2983, 2013 | 238 | 2013 |
G4 motifs affect origin positioning and efficiency in two vertebrate replicators AL Valton, V Hassan‐Zadeh, I Lema, N Boggetto, P Alberti, C Saintomé, ... The EMBO journal 33 (7), 732-746, 2014 | 225 | 2014 |
Interactions of cryptolepine and neocryptolepine with unusual DNA structures L Guittat, P Alberti, F Rosu, S Van Miert, E Thetiot, L Pieters, V Gabelica, ... Biochimie 85 (5), 535-547, 2003 | 199 | 2003 |
A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells D Gomez, A Guedin, JL Mergny, B Salles, JF Riou, MP Teulade-Fichou, ... Nucleic acids research 38 (20), 7187-7198, 2010 | 196 | 2010 |