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Paul Blakeley
Paul Blakeley
HKU
没有经过验证的电子邮件地址
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Defining the three cell lineages of the human blastocyst by single-cell RNA-seq
P Blakeley, NME Fogarty, I Del Valle, SE Wamaitha, TX Hu, K Elder, ...
Development 142 (18), 3151-3165, 2015
6302015
Genome editing reveals a role for OCT4 in human embryogenesis
NME Fogarty, A McCarthy, KE Snijders, BE Powell, N Kubikova, ...
Nature 550 (7674), 67-73, 2017
4672017
Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease
LA Hyslop, P Blakeley, L Craven, J Richardson, NME Fogarty, E Fragouli, ...
Nature 534 (7607), 383-386, 2016
3272016
Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells
SE Wamaitha, I Del Valle, LTY Cho, Y Wei, NME Fogarty, P Blakeley, ...
Genes & development 29 (12), 1239-1255, 2015
1382015
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders
E Evangelou, H Gao, C Chu, G Ntritsos, P Blakeley, AR Butts, R Pazoki, ...
Nature human behaviour 3 (9), 950-961, 2019
1062019
Addressing statistical biases in nucleotide-derived protein databases for proteogenomic search strategies
P Blakeley, IM Overton, SJ Hubbard
Journal of proteome research 11 (11), 5221-5234, 2012
1032012
SETDB1 links the meiotic DNA damage response to sex chromosome silencing in mice
T Hirota, P Blakeley, MN Sangrithi, SK Mahadevaiah, V Encheva, ...
Developmental cell 47 (5), 645-659. e6, 2018
822018
Investigating protein isoforms via proteomics: A feasibility study
P Blakeley, JA Siepen, C Lawless, SJ Hubbard
Proteomics 10 (6), 1127-1140, 2010
662010
GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits
R Pazoki, E Evangelou, D Mosen-Ansorena, RC Pinto, I Karaman, ...
Nature communications 10 (1), 3653, 2019
332019
A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway
BH Parikh, Z Liu, P Blakeley, Q Lin, M Singh, JY Ong, KH Ho, JW Lai, ...
Nature Communications 13 (1), 2796, 2022
242022
A pilot study on microRNA profile in tear fluid to predict response to anti-VEGF treatments for diabetic macular edema
HW Chan, B Yang, W Wong, P Blakeley, I Seah, QSW Tan, H Wang, ...
Journal of clinical medicine 9 (9), 2920, 2020
182020
Single-cell transcriptomics reveals maturation of transplanted stem cell–derived retinal pigment epithelial cells toward native state
BH Parikh, P Blakeley, K Regha, Z Liu, B Yang, M Bhargava, DSL Wong, ...
Proceedings of the National Academy of Sciences 120 (26), e2214842120, 2023
92023
Direct reprogramming of human embryonic to trophoblast stem cells
NME Fogarty, A Abdelbaki, A Mccarthy, L Devito, AE Chen, P Munusamy, ...
bioRxiv, 2021.08. 18.456785, 2021
52021
Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders
E Evangelou, H Gao, C Chu, G Ntritsos, P Blakeley, AR Butts, R Pazoki, ...
bioRxiv, 453332, 2018
52018
Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells
PA Balestrini, A Abdelbaki, A McCarthy, L Devito, CE Senner, AE Chen, ...
Development 151 (17), 2024
12024
Pathways underlying urinary sodium and potassium excretion and the link to blood pressure and cardiovascular disease
R Pazoki, E Evangelou, D Mosen-Ansorena, R Pinto, I Karaman, ...
Journal of Hypertension 37, e74, 2019
12019
Computational proteomics for genome annotation
P Blakeley
PQDT-UK & Ireland, 2013
12013
Bioinformatics in animal proteomics
P Blakeley, JC Wright, SJ Hubbard, AR Jones
Methods in Animal Proteomics, 103-119, 2011
12011
Single-Cell RNA-seq Defines the Three Cell Lineages of the Human Blastocyst
P Blakeley, NME Fogarty, I del Valle, SE Wamaitha, TX Hu, K Elder, ...
1
Animal and organoid models to elucidate the anti-fibrotic effect of steroid on biliary atresia
F Liu, VCH Lui, Z Wu, PD Blakeley, CSM Tang, PKH Tam, KKY Wong, ...
Pediatric Surgery International 40 (1), 214, 2024
2024
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