Insulin signaling to the glomerular podocyte is critical for normal kidney function GI Welsh, LJ Hale, V Eremina, M Jeansson, Y Maezawa, R Lennon, ... Cell metabolism 12 (4), 329-340, 2010 | 503 | 2010 |
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation KT Lawlor, JM Vanslambrouck, JW Higgins, A Chambon, K Bishard, ... Nature Biomaterials 63, 2020 | 316 | 2020 |
Evaluation of variability in human kidney organoids B Phipson, P X. Er, AN Combes, TA Forbes, SE Howden, L Zappia, ... Nature Methods, 2018 | 217 | 2018 |
3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening LJ Hale, SE Howden, B Phipson, A Lonsdale, P X.Er, I Ghobrial, S Hosawi, ... Nature Communications 9 (Article number: 5167), 2018 | 198 | 2018 |
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms T Forbes, S Howden, K Lawlor, B Phipson, L Hale, S Wilson, C Quinlan, ... The American Journal of Human Genetics, 2018 | 191 | 2018 |
Insulin-like growth factors and kidney disease LA Bach, LJ Hale American Journal of Kidney Diseases 65 (2), 327-336, 2015 | 127 | 2015 |
Insulin directly stimulates VEGF-A production in the glomerular podocyte LJ Hale, J Hurcombe, A Lay, B Santamaría, AM Valverde, MA Saleem, ... American journal of physiology-Renal physiology 305 (2), F182-F188, 2013 | 74 | 2013 |
Insulin signalling to the kidney in health and disease LJ Hale, RJM Coward Clinical science 124 (6), 351-370, 2013 | 60 | 2013 |
The insulin receptor and the kidney LJ Hale, RJM Coward Current opinion in nephrology and hypertension 22 (1), 100-106, 2013 | 47 | 2013 |
IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes B Santamaria, E Marquez, A Lay, RMM Carew, Á González-Rodríguez, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (12), 3224-3234, 2015 | 39 | 2015 |
Genetic deletion of cell division autoantigen 1 retards diabetes-associated renal injury Z Chai, A Dai, Y Tu, J Li, T Wu, Y Wang, LJ Hale, F Koentgen, MC Thomas, ... Journal of the American Society of Nephrology 24 (11), 1782-1792, 2013 | 32 | 2013 |
Generating Kidney from Stem Cells MH Little, LJ Hale, SE Howden, SV Kumar Annual Review of Physiology 81, 335–357, 2019 | 28 | 2019 |
Insulin‐like growth factor‐II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse LJ Hale, GI Welsh, CM Perks, JA Hurcombe, S Moore, I Hers, MA Saleem, ... The Journal of pathology 230 (1), 95-106, 2013 | 27 | 2013 |
Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ... bioRxiv, 505396, 2018 | 26 | 2018 |
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes AC Lay, LJ Hale, H Stowell-Connolly, RJP Pope, V Nair, W Ju, E Marquez, ... Diabetologia, 2021 | 21 | 2021 |
Associations with age and glomerular filtration rate in a referred population with chronic kidney disease: Methods and baseline data from a UK multicentre cohort study (NURTuRE … Nephrology Dialysis Transplantation, 2023 | 10 | 2023 |
Transcriptional evaluation of the developmental accuracy, reproducibility and robustness of kidney organoids derived from human pluripotent stem cells B Phipson, PX Er, L Hale, D Yen, K Lawlor, M Takasato, J Sun, ... bioRxiv, 238428, 2017 | 4 | 2017 |
Generating Human Glomeruli from Pluripotent Stem Cells for Disease Modelling and Drug Screening LJ Hale, MH Little Methods Molecular Biology: Kidney Research Experimental Protocols 2664, 55-68, 2023 | 2 | 2023 |
Shining a Light on Alport Syndrome L Hale, M Little Cell Chemical Biology 25 (5), 497-498, 2018 | 1 | 2018 |
Optimisation of Kidney Organoids as a Reproducible and Developmentally Accurate Model of Human Kidney Development and Disease MH Little, PX Er, B Phipson, J Vanslambrouck, S Howden, L Hale, ... Journal of Gene Medicine 20 (1), 2018 | | 2018 |