| GABAA receptor signalling mechanisms revealed by structural pharmacology S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ... Nature 565 (7740), 454-459, 2019 | 495 | 2019 |
| Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ... Nature 565 (7740), 516-520, 2019 | 305 | 2019 |
| Extracellular K+ and Opening of Voltage-Gated Potassium Channels Activate T Cell Integrin Function: Physical and Functional Association between Kv1.3 … M Levite, L Cahalon, A Peretz, R Hershkoviz, A Sobko, A Ariel, R Desai, ... The Journal of experimental medicine 191 (7), 1167-1176, 2000 | 255 | 2000 |
| Slack and Slick KNa channels regulate the accuracy of timing of auditory neurons B Yang, R Desai, LK Kaczmarek Journal of Neuroscience 27 (10), 2617-2627, 2007 | 123 | 2007 |
| Tryptophan mutations at azi-etomidate photo-incorporation sites on α1 or β2 subunits enhance GABAA receptor gating and reduce etomidate modulation D Stewart, R Desai, Q Cheng, A Liu, SA Forman Molecular Pharmacology 74 (6), 1687-1695, 2008 | 88 | 2008 |
| Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels LK Kaczmarek, A Bhattacharjee, R Desai, L Gan, P Song, CAA von Hehn, ... Hearing research 206 (1-2), 133-145, 2005 | 73 | 2005 |
| Kv3. 3 channels bind Hax-1 and Arp2/3 to assemble a stable local actin network that regulates channel gating Y Zhang, XF Zhang, MR Fleming, A Amiri, L El-Hassar, AA Surguchev, ... Cell 165 (2), 434-448, 2016 | 72 | 2016 |
| Ca2+-activated K+ channels in human leukemic Jurkat T cells: molecular cloning, biochemical and functional characterization R Desai, A Peretz, H Idelson, P Lazarovici, B Attali Journal of Biological Chemistry 275 (51), 39954-39963, 2000 | 71 | 2000 |
| γ-Amino butyric acid type A receptor mutations at β2N265 alter etomidate efficacy while preserving basal and agonist-dependent activity R Desai, D Ruesch, SA Forman The Journal of the American Society of Anesthesiologists 111 (4), 774-784, 2009 | 61 | 2009 |
| Protein kinase C modulates inactivation of Kv3. 3 channels R Desai, J Kronengold, J Mei, SA Forman, LK Kaczmarek Journal of biological chemistry 283 (32), 22283-22294, 2008 | 52 | 2008 |
| Differential assembly diversifies GABAA receptor structures and signalling A Sente, R Desai, K Naydenova, T Malinauskas, Y Jounaidi, J Miehling, ... Nature 604 (7904), 190-194, 2022 | 47 | 2022 |
| High‐level expression and purification of Cys‐loop ligand‐gated ion channels in a tetracycline‐inducible stable mammalian cell line: GABAA and serotonin receptors Z Dostalova, A Liu, X Zhou, SL Farmer, ES Krenzel, E Arevalo, R Desai, ... Protein Science 19 (9), 1728-1738, 2010 | 46 | 2010 |
| Requirement of Voltage-Gated Calcium Channel β4 Subunit for T Lymphocyte Functions A Badou, S Basavappa, R Desai, YQ Peng, D Matza, WZ Mehal, ... Science 307 (5706), 117-121, 2005 | 44 | 2005 |
| Human α1β3γ2L gamma‐aminobutyric acid type A receptors: high‐level production and purification in a functional state Z Dostalova, X Zhou, A Liu, X Zhang, Y Zhang, R Desai, SA Forman, ... Protein Science 23 (2), 157-166, 2014 | 33 | 2014 |
| Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors DS Stewart, M Hotta, G Li, R Desai, DC Chiara, RW Olsen, SA Forman Journal of Biological Chemistry 288 (42), 30373-30386, 2013 | 33 | 2013 |
| p-Trifluoromethyldiazirinyl-etomidate: A Potent Photoreactive General Anesthetic Derivative of Etomidate That Is Selective for Ligand-Gated Cationic Ion Channels SS Husain, D Stewart, R Desai, AK Hamouda, SGD Li, E Kelly, ... Journal of medicinal chemistry 53 (17), 6432-6444, 2010 | 30 | 2010 |
| Positive and negative allosteric modulation of an α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor by binding to a site in the transmembrane domain at the γ+-β− interface SS Jayakar, X Zhou, PY Savechenkov, DC Chiara, R Desai, KS Bruzik, ... Journal of Biological Chemistry 290 (38), 23432-23446, 2015 | 29 | 2015 |
| State-dependent etomidate occupancy of its allosteric agonist sites measured in a cysteine-substituted GABAA receptor DS Stewart, M Hotta, R Desai, SA Forman Molecular pharmacology 83 (6), 1200-1208, 2013 | 25 | 2013 |
| Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands PY Savechenkov, DC Chiara, R Desai, AT Stern, X Zhou, AM Ziemba, ... European journal of medicinal chemistry 136, 334-347, 2017 | 16 | 2017 |
| The pyrrole etomidate analog carboetomidate potently inhibits human 5-HT3A receptor function: comparisons with etomidate and potential implications for emetogenesis R Desai, KW Miller, DE Raines Anesthesia & Analgesia 116 (3), 573-579, 2013 | 12 | 2013 |
