Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice K Rezai-Zadeh, D Shytle, N Sun, T Mori, H Hou, D Jeanniton, J Ehrhart, ... Journal of Neuroscience 25 (38), 8807-8814, 2005 | 835 | 2005 |
Cholinergic modulation of microglial activation by α7 nicotinic receptors RD Shytle, T Mori, K Townsend, M Vendrame, N Sun, J Zeng, J Ehrhart, ... Journal of neurochemistry 89 (2), 337-343, 2004 | 731 | 2004 |
Caffeine protects Alzheimer’s mice against cognitive impairment and reduces brain β-amyloid production GW Arendash, W Schleif, K Rezai-Zadeh, EK Jackson, LC Zacharia, ... Neuroscience 142 (4), 941-952, 2006 | 627 | 2006 |
The microglial" activation" continuum: from innate to adaptive responses T Town, V Nikolic, J Tan Journal of neuroinflammation 2, 1-10, 2005 | 605 | 2005 |
Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice K Rezai-Zadeh, GW Arendash, H Hou, F Fernandez, M Jensen, ... Brain research 1214, 177-187, 2008 | 534 | 2008 |
Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology T Town, Y Laouar, C Pittenger, T Mori, CA Szekely, J Tan, RS Duman, ... Nature medicine 14 (6), 681-687, 2008 | 489 | 2008 |
Microglial activation resulting from CD40-CD40L interaction after β-amyloid stimulation J Tan, T Town, D Paris, T Mori, Z Suo, F Crawford, MP Mattson, RA Flavell, ... Science 286 (5448), 2352-2355, 1999 | 475 | 1999 |
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation J Ehrhart, D Obregon, T Mori, H Hou, N Sun, Y Bai, T Klein, F Fernandez, ... Journal of neuroinflammation 2, 1-13, 2005 | 456 | 2005 |
Caffeine reverses cognitive impairment and decreases brain amyloid-β levels in aged Alzheimer's disease mice GW Arendash, T Mori, C Cao, M Mamcarz, M Runfeldt, A Dickson, ... Journal of Alzheimer's disease 17 (3), 661-680, 2009 | 399 | 2009 |
Inflammaging as a prodrome to Alzheimer's disease B Giunta, F Fernandez, WV Nikolic, D Obregon, E Rrapo, T Town, J Tan Journal of neuroinflammation 5, 1-15, 2008 | 397 | 2008 |
Microglia activation as a biomarker for traumatic brain injury DG Hernandez-Ontiveros, N Tajiri, S Acosta, B Giunta, J Tan, ... Frontiers in neurology 4, 30, 2013 | 339 | 2013 |
Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease A Smith, B Giunta, PC Bickford, M Fountain, J Tan, RD Shytle International journal of pharmaceutics 389 (1-2), 207-212, 2010 | 308 | 2010 |
Electromagnetic field treatment protects against and reverses cognitive impairment in Alzheimer's disease mice GW Arendash, J Sanchez-Ramos, T Mori, M Mamcarz, X Lin, M Runfeldt, ... Journal of Alzheimer's disease 19 (1), 191-210, 2010 | 277 | 2010 |
Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease Y Xiang, XL Bu, YH Liu, C Zhu, LL Shen, SS Jiao, XY Zhu, B Giunta, J Tan, ... Acta neuropathologica 130, 487-499, 2015 | 251 | 2015 |
ADAM10 activation is required for green tea (–)-epigallocatechin-3-gallate-induced α-secretase cleavage of amyloid precursor protein DF Obregon, K Rezai-Zadeh, Y Bai, N Sun, H Hou, J Ehrhart, J Zeng, ... Journal of Biological Chemistry 281 (24), 16419-16427, 2006 | 250 | 2006 |
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice J Tan, T Town, F Crawford, T Mori, A DelleDonne, R Crescentini, ... Nature neuroscience 5 (12), 1288-1293, 2002 | 244 | 2002 |
Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics D Morgan, MN Gordon, J Tan, D Wilcock, AM Rojiani Journal of Neuropathology & Experimental Neurology 64 (9), 743-753, 2005 | 240 | 2005 |
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease T Mori, N Koyama, GW Arendash, Y Horikoshi‐Sakuraba, J Tan, T Town Glia 58 (3), 300-314, 2010 | 235 | 2010 |
T-cells in Alzheimer’s disease T Town, J Tan, RA Flavell, M Mullan Neuromolecular medicine 7, 255-264, 2005 | 235 | 2005 |
Mitochondrial amyloid-β levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's … N Dragicevic, M Mamcarz, Y Zhu, R Buzzeo, J Tan, GW Arendash, ... Journal of Alzheimer's Disease 20 (s2), S535-S550, 2010 | 231 | 2010 |