Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B U Viswanathan, N Mani, Z Hu, H Ban, Y Du, J Hu, J Chang, JT Guo Antiviral research 182, 104917, 2020 | 78 | 2020 |
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal U Viswanathan, SM Tomlinson, JM Fonner, SA Mock, SJ Watowich Journal of chemical information and modeling 54 (10), 2816-2825, 2014 | 55 | 2014 |
Discovery and mechanistic study of a novel human-stimulator-of-interferon-genes agonist X Zhang, B Liu, L Tang, Q Su, N Hwang, M Sehgal, J Cheng, J Ma, ... ACS infectious diseases 5 (7), 1139-1149, 2019 | 51 | 2019 |
Importance of dynamic hydrogen bonds and reorientation barriers in proton transport C Nagamani, U Viswanathan, C Versek, MT Tuominen, SM Auerbach, ... Chemical Communications 47 (23), 6638-6640, 2011 | 35 | 2011 |
Vibrational predissociation spectroscopy and theory of Ar-tagged, protonated Imidazole (Im) Im1–3H+· Ar clusters HK Gerardi, GH Gardenier, U Viswanathan, SM Auerbach, MA Johnson Chemical Physics Letters 501 (4-6), 172-178, 2011 | 25 | 2011 |
CpAMs induce assembly of HBV capsids with altered electrophoresis mobility: Implications for mechanism of inhibiting pgRNA packaging S Wu, Y Luo, U Viswanathan, J Kulp, J Cheng, Z Hu, Q Xu, Y Zhou, ... Antiviral research 159, 1-12, 2018 | 21 | 2018 |
Modeling energy landscapes of proton motion in nonaqueous, tethered proton wires U Viswanathan, D Basak, D Venkataraman, JT Fermann, SM Auerbach The Journal of Physical Chemistry A 115 (21), 5423-5434, 2011 | 21 | 2011 |
Modeling proton jumps in HY zeolite: effects of acid site heterogeneity U Viswanathan, JT Fermann, LK Toy, SM Auerbach, T Vreven, MJ Frisch The Journal of Physical Chemistry C 111 (49), 18341-18347, 2007 | 19 | 2007 |
Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis H Liu, J Cheng, U Viswanathan, J Chang, F Lu, JT Guo PLoS pathogens 17 (11), e1010057, 2021 | 18 | 2021 |
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice T Sato, CDC Andrade, SH Yoon, Y Zhao, WJ Greenlee, PC Weber, ... Proceedings of the National Academy of Sciences 119 (50), e2214396119, 2022 | 16 | 2022 |
Profiling the circulating mRNA transcriptome in human liver disease A Sayeed, BE Dalvano, DE Kaplan, U Viswanathan, J Kulp, AH Janneh, ... Oncotarget 11 (23), 2216, 2020 | 15 | 2020 |
Modeling nonaqueous proton wires built from helical peptides: biased proton transfer driven by helical dipoles GE López, I Colón-Díaz, A Cruz, S Ghosh, SB Nicholls, U Viswanathan, ... The Journal of Physical Chemistry A 116 (4), 1283-1288, 2012 | 14 | 2012 |
Simulating hydrogen-bond clustering and phase behaviour of imidazole oligomers JA Harvey, D Basak, D Venkataraman, SM Auerbach Molecular Physics 110 (9-10), 957-966, 2012 | 13 | 2012 |
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators Y Luo, J Cheng, Z Hu, H Ban, S Wu, N Hwang, J Kulp, Y Li, Y Du, J Chang, ... Antiviral research 191, 105080, 2021 | 11 | 2021 |
A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles S Yang, Z Shen, Y Kang, L Sun, U Viswanathan, H Guo, T Zhou, X Dai, ... Journal of virology 95 (8), 10.1128/jvi. 02399-20, 2021 | 6 | 2021 |
4-Oxooctahydroquinoline-1 (2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators N Hwang, H Ban, S Wu, K McGuire, E Hernandez, J Chen, Q Zhao, ... Bioorganic & medicinal chemistry letters 58, 128518, 2022 | 4 | 2022 |
Precision Discovery of Novel Inhibitors of Human Cancer Target HsMetAP1 from Vast Unexplored Metagenomic Diversity OW Liu, S Akers, G Alvarez, S Brown, W Cai, Z Charlop-Powers, ... bioRxiv, 2022.06. 11.495772, 2022 | 1 | 2022 |
Small-molecule inhibitors of dengue virus proteases SJ Watowich, U Viswanathan US Patent 9,408,813, 2016 | 1 | 2016 |
Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly N Hwang, S Wu, H Ban, H Luo, J Ma, J Cheng, Q Zhao, JA Laney, N Du, ... European Journal of Medicinal Chemistry 259, 115634, 2023 | | 2023 |
Molecular modeling of proton transfer mechanisms, energetics and rates in zeolites and proton exchange membranes U Viswanathan University of Massachusetts Amherst, 2011 | | 2011 |