关注
Gabriele Büchel
Gabriele Büchel
Professor of Dynamics of Protein complexes
在 uni-wuerzburg.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase
S Herold, J Kalb, G Büchel, CP Ade, A Baluapuri, J Xu, J Koster, D Solvie, ...
Nature 567 (7749), 545-549, 2019
922019
Association with Aurora-A controls N-MYC-dependent promoter escape and pause release of RNA polymerase II during the cell cycle
G Büchel, A Carstensen, KY Mak, I Roeschert, E Leen, O Sumara, ...
Cell reports 21 (12), 3483-3497, 2017
902017
Potential of novel antiretrovirals to modulate expression and function of drug transporters in vitro
NCL Zembruski, G Büchel, L Jödicke, M Herzog, WE Haefeli, J Weiss
Journal of antimicrobial chemotherapy 66 (4), 802-812, 2011
842011
Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma
I Roeschert, E Poon, AG Henssen, H Dorado Garcia, M Gatti, C Giansanti, ...
Nature cancer 2 (3), 312-326, 2021
692021
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer
C Kalogirou, J Linxweiler, P Schmucker, MT Snaebjornsson, W Schmitz, ...
Nature communications 12 (1), 5066, 2021
502021
Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN‐amplified neuroblastoma
A Schramm, J Köster, T Marschall, M Martin, M Schwermer, K Fielitz, ...
International journal of cancer 132 (3), E106-E115, 2013
462013
Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers
AJ Wolpaw, R Bayliss, G Büchel, CV Dang, M Eilers, WC Gustafson, ...
Cancer Research 81 (7), 1627-1632, 2021
402021
Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma
G Büchel, JH Schulte, L Harrison, K Batzke, U Schüller, W Hansen, ...
Oncoimmunology 5 (5), e1131378, 2016
222016
LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
H Alborzinia, Z Chen, U Yildiz, FP Freitas, FCE Vogel, JP Varga, J Batani, ...
EMBO Molecular Medicine 15 (8), e18014, 2023
182023
TrkB-target galectin-1 impairs immune activation and radiation responses in neuroblastoma: implications for tumour therapy
K Batzke, G Büchel, W Hansen, A Schramm
International journal of molecular sciences 19 (3), 718, 2018
142018
Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers
H Alborzinia, Z Chen, U Yildiz, FP Freitas, FCE Vogel, J Varga, J Batani, ...
bioRxiv, 2022.05. 17.492172, 2022
62022
The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
D Papadopoulos, SA Ha, D Fleischhauer, L Uhl, TJ Russell, I Mikicic, ...
Molecular Cell 84 (11), 2070-2086. e20, 2024
12024
Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II
R Vidal, E Leen, S Herold, M Müller, D Fleischhauer, C Schülein-Völk, ...
bioRxiv, 2023.11. 18.567687, 2023
12023
Direct RNA-binding by MYCN mediates feedback from RNA processing to transcription control
D Papadopoulos, SA Ha, D Fleischhauer, L Uhl, K Schneider, I Mikicic, ...
bioRxiv, 2023.08. 16.553474, 2023
12023
Einfluss der Galectin-1 Expression auf die Tumor-Immun-Interaktion im Neuroblastom
G Büchel
Dissertation, Duisburg, Essen, Universität Duisburg-Essen, 2015, 2016
12016
POTENTIAL OF NOVEL ANTIRETROVIRALS TO MODULATE EXPRESSION AND FUNCTION OF ABC-TRANSPORTERS: 59
N Zembruski, G Büchel, L Jödicke, W Haefeli, J Weiss
British Journal of Clinical Pharmacology 68, 2009
12009
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy
L Grunewald, L Andersch, K Helmsauer, S Schwiebert, A Klaus, ...
bioRxiv, 2024.01. 27.576592, 2024
2024
系统目前无法执行此操作,请稍后再试。
文章 1–17