DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity C Lu, J Guan, S Lu, Q Jin, B Rousseau, T Lu, D Stephens, H Zhang, J Zhu, ... Cancer cell 39 (1), 96-108. e6, 2021 | 192 | 2021 |
Targeting tumors with IL-10 prevents dendritic cell-mediated CD8+ T cell apoptosis J Qiao, Z Liu, C Dong, Y Luan, A Zhang, C Moore, K Fu, J Peng, Y Wang, ... Cancer cell 35 (6), 901-915. e4, 2019 | 128 | 2019 |
Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling C Han, Z Liu, Y Zhang, A Shen, C Dong, A Zhang, C Moore, Z Ren, C Lu, ... Nature immunology 21 (5), 546-554, 2020 | 100 | 2020 |
Telomere stress potentiates STING-dependent anti-tumor immunity I Mender, A Zhang, Z Ren, C Han, Y Deng, S Siteni, H Li, J Zhu, A Vemula, ... Cancer cell 38 (3), 400-411. e6, 2020 | 85 | 2020 |
Targeting innate sensing in the tumor microenvironment to improve immunotherapy Z Liu, C Han, YX Fu Cellular & molecular immunology 17 (1), 13-26, 2020 | 85 | 2020 |
Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy M Luo, Z Liu, X Zhang, C Han, LZ Samandi, C Dong, BD Sumer, J Lea, ... Journal of Controlled Release 300, 154-160, 2019 | 74 | 2019 |
NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance X Li, Z Liu, A Zhang, C Han, A Shen, L Jiang, DA Boothman, J Qiao, ... Nature communications 10 (1), 3251, 2019 | 69 | 2019 |
Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration K Yang, W Han, X Jiang, A Piffko, J Bugno, C Han, S Li, H Liang, Z Xu, ... Nature Nanotechnology 17 (12), 1322-1331, 2022 | 67 | 2022 |
Personalized ultrafractionated stereotactic adaptive radiotherapy (PULSAR) in preclinical models enhances single-agent immune checkpoint blockade C Moore, CC Hsu, WM Chen, BPC Chen, C Han, M Story, T Aguilera, ... International Journal of Radiation Oncology* Biology* Physics 110 (5), 1306-1316, 2021 | 67 | 2021 |
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells H Li, Z Liu, L Liu, H Zhang, C Han, L Girard, H Park, A Zhang, C Dong, ... Cell Reports Medicine 3 (3), 2022 | 51 | 2022 |
The AIM2 and NLRP3 inflammasomes trigger IL-1–mediated antitumor effects during radiation C Han, V Godfrey, Z Liu, Y Han, L Liu, H Peng, RR Weichselbaum, H Zaki, ... Science immunology 6 (59), eabc6998, 2021 | 44 | 2021 |
Rejuvenation of tumour-specific T cells through bispecific antibodies targeting PD-L1 on dendritic cells L Liu, J Chen, J Bae, H Li, Z Sun, C Moore, E Hsu, C Han, J Qiao, YX Fu Nature biomedical engineering 5 (11), 1261-1273, 2021 | 43 | 2021 |
Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity Z Liu, C Han, C Dong, A Shen, E Hsu, Z Ren, C Lu, L Liu, A Zhang, ... Science immunology 4 (38), eaav6473, 2019 | 36 | 2019 |
A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum Y Zhang, B Li, S Cananzi, C Han, LL Wang, Y Zou, YX Fu, GC Hon, ... Proceedings of the National Academy of Sciences 119 (11), e2107339119, 2022 | 32 | 2022 |
ZAP inhibits murine gammaherpesvirus 68 ORF64 expression and is antagonized by RTA Y Xuan, D Gong, J Qi, C Han, H Deng, G Gao Journal of virology 87 (5), 2735-2743, 2013 | 31 | 2013 |
Replication and transcription activator (RTA) of murine gammaherpesvirus 68 binds to an RTA-responsive element and activates the expression of ORF18 Y Hong, J Qi, D Gong, C Han, H Deng Journal of virology 85 (21), 11338-11350, 2011 | 19 | 2011 |
Small molecular drugs reshape tumor microenvironment to synergize with immunotherapy C Han, A Zhang, Z Liu, C Moore, YX Fu Oncogene 40 (5), 885-898, 2021 | 15 | 2021 |
β-Catenin regulates tumor-derived PD-L1 C Han, YX Fu The Journal of experimental medicine 217 (11), 2020 | 14 | 2020 |
Murine Gammaherpesvirus 68 ORF48 Is an RTA-Responsive Gene Product and Functions in both Viral Lytic Replication and Latency during In Vivo Infection J Qi, C Han, D Gong, P Liu, S Zhou, H Deng Journal of virology 89 (11), 5788-5800, 2015 | 14 | 2015 |
Crystal structure and functional implication of the RUN domain of human NESCA Q Sun, C Han, L Liu, Y Wang, H Deng, L Bai, T Jiang Protein & cell 3 (8), 609-617, 2012 | 9 | 2012 |