| A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ... Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017 | 308 | 2017 |
| Nucleation and growth of amino acid and peptide supramolecular polymers through liquid–liquid phase separation C Yuan, A Levin, W Chen, R Xing, Q Zou, TW Herling, PK Challa, ... Angewandte Chemie International Edition 58 (50), 18116-18123, 2019 | 302 | 2019 |
| Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, ... Proceedings of the National Academy of Sciences 114 (2), E200-E208, 2017 | 212 | 2017 |
| Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ... Nature communications 10 (1), 225, 2019 | 135 | 2019 |
| Twist-bend nematic liquid crystals in high magnetic fields PK Challa, V Borshch, O Parri, CT Imrie, SN Sprunt, JT Gleeson, ... Physical Review E 89 (6), 060501, 2014 | 129 | 2014 |
| Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, ... ACS chemical biology 13 (8), 2308-2319, 2018 | 108 | 2018 |
| Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning PK Challa, T Kartanas, J Charmet, TPJ Knowles Biomicrofluidics 11 (1), 2017 | 67 | 2017 |
| Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, ... Journal of neuroscience methods 306, 57-67, 2018 | 59 | 2018 |
| Attoliter protein nanogels from droplet nanofluidics for intracellular delivery Z Toprakcioglu, PK Challa, DB Morse, T Knowles Science Advances 6 (6), eaay7952, 2020 | 57 | 2020 |
| Scalable integration of nano-, and microfluidics with hybrid two-photon lithography O Vanderpoorten, Q Peter, PK Challa, UF Keyser, J Baumberg, ... Microsystems & nanoengineering 5 (1), 40, 2019 | 56 | 2019 |
| Label-free analysis of protein aggregation and phase behavior Z Toprakcioglu, P Challa, C Xu, TPJ Knowles ACS nano 13 (12), 13940-13948, 2019 | 53 | 2019 |
| On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, ... Lab on a Chip 18 (1), 162-170, 2018 | 52 | 2018 |
| Real-time intrinsic fluorescence visualization and sizing of proteins and protein complexes in microfluidic devices PK Challa, Q Peter, MA Wright, Y Zhang, KL Saar, JA Carozza, ... Analytical chemistry 90 (6), 3849-3855, 2018 | 45 | 2018 |
| Fluctuation modes of a twist-bend nematic liquid crystal Z Parsouzi, SM Shamid, V Borshch, PK Challa, AR Baldwin, MG Tamba, ... Physical Review X 6 (2), 021041, 2016 | 45 | 2016 |
| Observation of Molecular Self-assembly Events in Massively Parallel Microdroplet Arrays Z Toprakcioglu, PK Challa, A Levin, T Knowles Lab on a Chip, 2018 | 37 | 2018 |
| Enhancing the resolution of micro free flow electrophoresis through spatially controlled sample injection KL Saar, T Müller, J Charmet, PK Challa, TPJ Knowles Analytical chemistry 90 (15), 8998-9005, 2018 | 36 | 2018 |
| Gradient-free determination of isoelectric points of proteins on chip U Łapińska, KL Saar, EV Yates, TW Herling, T Müller, PK Challa, ... Physical Chemistry Chemical Physics 19 (34), 23060-23067, 2017 | 29 | 2017 |
| Enhanced quality factor label-free biosensing with micro-cantilevers integrated into microfluidic systems T Kartanas, V Ostanin, PK Challa, R Daly, J Charmet, TPJ Knowles Analytical chemistry 89 (22), 11929-11936, 2017 | 24 | 2017 |
| Low-Cost microfabrication tool box J Charmet, R Rodrigues, E Yildirim, PK Challa, B Roberts, R Dallmann, ... Micromachines 11 (2), 135, 2020 | 20 | 2020 |
| Rapid two-dimensional characterisation of proteins in solution KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles Microsystems & Nanoengineering 5 (1), 33, 2019 | 20 | 2019 |
Tuomas KnowlesProfessor of Physical Chemistry and Biophysics, University of Cambridge在 cam.ac.uk 的电子邮件经过验证
