IgG subclasses and allotypes: from structure to effector functions G Vidarsson, G Dekkers, T Rispens Frontiers in immunology 5, 520, 2014 | 3092 | 2014 |
Decoding the human immunoglobulin G-glycan repertoire reveals a spectrum of Fc-receptor-and complement-mediated-effector activities G Dekkers, L Treffers, R Plomp, AEH Bentlage, M de Boer, ... Frontiers in immunology 8, 877, 2017 | 353 | 2017 |
Affinity of human IgG subclasses to mouse Fc gamma receptors G Dekkers, AEH Bentlage, TC Stegmann, HL Howie, ... MAbs 9 (5), 767-773, 2017 | 226 | 2017 |
Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans G Dekkers, R Plomp, CAM Koeleman, R Visser, HH Von Horsten, ... Scientific reports 6 (1), 36964, 2016 | 143 | 2016 |
Hinge-region O-glycosylation of human immunoglobulin G3 (IgG3)*[S] R Plomp, G Dekkers, Y Rombouts, R Visser, CAM Koeleman, ... Molecular & cellular proteomics 14 (5), 1373-1384, 2015 | 127 | 2015 |
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages SQ Nagelkerke, G Dekkers, I Kustiawan, FS van de Bovenkamp, ... Blood, The Journal of the American Society of Hematology 124 (25), 3709-3718, 2014 | 118 | 2014 |
Glycosylation pattern of anti‐platelet IgG is stable during pregnancy and predicts clinical outcome in alloimmune thrombocytopenia ME Sonneveld, S Natunen, S Sainio, CAM Koeleman, S Holst, G Dekkers, ... British journal of haematology 174 (2), 310-320, 2016 | 112 | 2016 |
Novel Concepts of altered immunoglobulin G Galactosylation in autoimmune diseases G Dekkers, T Rispens, G Vidarsson Frontiers in immunology 9, 553, 2018 | 104 | 2018 |
Identification of sequence variants influencing immunoglobulin levels S Jonsson, G Sveinbjornsson, AL de Lapuente Portilla, B Swaminathan, ... Nature genetics 49 (8), 1182-1191, 2017 | 100 | 2017 |
Enhanced effector functions due to antibody defucosylation depend on the effector cell Fcγ receptor profile CW Bruggeman, G Dekkers, AEH Bentlage, LW Treffers, SQ Nagelkerke, ... The Journal of Immunology 199 (1), 204-211, 2017 | 80 | 2017 |
Functional attributes of antibodies, effector cells, and target cells affecting NK cell–mediated antibody-dependent cellular cytotoxicity AR Temming, SW de Taeye, EL de Graaf, LA de Neef, G Dekkers, ... The Journal of Immunology 203 (12), 3126-3135, 2019 | 78 | 2019 |
Human DC-SIGN and CD23 do not interact with human IgG AR Temming, G Dekkers, FS van de Bovenkamp, HR Plomp, ... Scientific reports 9 (1), 9995, 2019 | 55 | 2019 |
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1 LE McCoy, L Rutten, D Frampton, I Anderson, L Granger, ... PLoS pathogens 10 (12), e1004552, 2014 | 55 | 2014 |
Conserved FcγR-glycan discriminates between fucosylated and afucosylated IgG in humans and mice G Dekkers, AEH Bentlage, R Plomp, R Visser, CAM Koeleman, ... Molecular immunology 94, 54-60, 2018 | 36 | 2018 |
Glycoengineering HIV-1 Env creates ‘supercharged’and ‘hybrid’glycans to increase neutralizing antibody potency, breadth and saturation ET Crooks, SL Grimley, M Cully, K Osawa, G Dekkers, K Saunders, ... PLoS pathogens 14 (5), e1007024, 2018 | 30 | 2018 |
IgG subclass determines suppression versus enhancement of humoral alloimmunity to kell RBC antigens in mice P Shinde, HL Howie, TC Stegmann, AM Hay, HR Waterman, Z Szittner, ... Frontiers in immunology 11, 1516, 2020 | 17 | 2020 |
Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation WJJ Falkenburg, AC Kempers, G Dekkers, P Ooijevaar-de Heer, ... Rheumatology 56 (11), 2025-2030, 2017 | 15 | 2017 |
Anti-HIV-1 Nanobody-IgG1 constructs with improved neutralization potency and the ability to mediate fc effector functions AI Schriek, MM van Haaren, M Poniman, G Dekkers, AEH Bentlage, ... Frontiers in immunology 13, 893648, 2022 | 12 | 2022 |
IgG glyco-engineering to improve IVIg potency CW Bruggeman, G Dekkers, R Visser, NWM Goes, TK Van den Berg, ... Frontiers in immunology 9, 2442, 2018 | 12 | 2018 |
Biophysical evaluation of rhesus macaque Fc gamma receptors reveals similar IgG Fc glycoform preferences to human receptors AR Crowley, NY Osei-Owusu, G Dekkers, W Gao, M Wuhrer, DM Magnani, ... Frontiers in Immunology 12, 754710, 2021 | 9 | 2021 |