RETRACTED ARTICLE: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins J Martinez, RKS Malireddi, Q Lu, LD Cunha, S Pelletier, S Gingras, ... Nature cell biology 17 (7), 893-906, 2015 | 828 | 2015 |
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia Z Gu, ML Churchman, KG Roberts, I Moore, X Zhou, J Nakitandwe, ... Nature genetics 51 (2), 296-307, 2019 | 494 | 2019 |
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration RM Perciavalle, DP Stewart, B Koss, J Lynch, S Milasta, M Bathina, ... Nature cell biology 14 (6), 575-583, 2012 | 465 | 2012 |
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome P Samir, S Kesavardhana, DM Patmore, S Gingras, RKS Malireddi, ... Nature 573 (7775), 590-594, 2019 | 321 | 2019 |
BOK is a non-canonical BCL-2 family effector of apoptosis regulated by ER-associated degradation F Llambi, YM Wang, B Victor, M Yang, DM Schneider, S Gingras, ... Cell 165 (2), 421-433, 2016 | 264 | 2016 |
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ... Journal of Experimental Medicine 217 (3), 2020 | 231 | 2020 |
Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors S Pelletier, F Duhamel, P Coulombe, MR Popoff, S Meloche Molecular and cellular biology 23 (4), 1316-1333, 2003 | 191 | 2003 |
NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer R Karki, SM Man, RKS Malireddi, S Kesavardhana, Q Zhu, AR Burton, ... Nature 540 (7634), 583-587, 2016 | 179 | 2016 |
Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during … P Coulombe, G Rodier, S Pelletier, J Pellerin, S Meloche Molecular and cellular biology, 2003 | 169 | 2003 |
Differential roles of caspase-1 and caspase-11 in infection and inflammation SM Man, R Karki, B Briard, A Burton, S Gingras, S Pelletier, ... Scientific reports 7 (1), 45126, 2017 | 146 | 2017 |
Mouse genome engineering via CRISPR-Cas9 for study of immune function S Pelletier, S Gingras, DR Green Immunity 42 (1), 18-27, 2015 | 109 | 2015 |
Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity M Funakoshi-Tago, S Pelletier, H Moritake, E Parganas, JN Ihle Molecular and cellular biology, 2008 | 109 | 2008 |
Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2 M Funakoshi‐Tago, S Pelletier, T Matsuda, E Parganas, JN Ihle The EMBO journal 25 (20), 4763-4772, 2006 | 108 | 2006 |
Caspase-8-dependent inflammatory responses are controlled by its adaptor, FADD, and necroptosis B Tummers, L Mari, CS Guy, BL Heckmann, DA Rodriguez, S Rühl, ... Immunity 52 (6), 994-1006. e8, 2020 | 99 | 2020 |
Amino acids license kinase mTORC1 activity and Treg cell function via small G proteins Rag and Rheb H Shi, NM Chapman, J Wen, C Guy, L Long, Y Dhungana, S Rankin, ... Immunity 51 (6), 1012-1027. e7, 2019 | 96 | 2019 |
Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function S Pelletier, S Gingras, M Funakoshi-Tago, S Howell, JN Ihle Molecular and cellular biology 26 (22), 8527-8538, 2006 | 82 | 2006 |
Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function SK Ippagunta, R Gangwar, D Finkelstein, P Vogel, S Pelletier, S Gingras, ... Proceedings of the National Academy of Sciences 113 (41), E6162-E6171, 2016 | 78 | 2016 |
Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor … JL Rouleau, G Kapuku, S Pelletier, H Gosselin, A Adam, C Gagnon, ... Circulation 104 (8), 939-944, 2001 | 68 | 2001 |
Cyclic AMP induces morphological changes of vascular smooth muscle cells by inhibiting a Rac‐dependent signaling pathway S Pelletier, C Julien, MR Popoff, N Lamarche‐Vane, S Meloche Journal of cellular physiology 204 (2), 412-422, 2005 | 60 | 2005 |
CRISPR-Cas9–Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes X Lin, S Pelletier, S Gingras, S Rigaud, CJ Maine, K Marquardt, YD Dai, ... Diabetes 65 (8), 2134-2138, 2016 | 44 | 2016 |