Rieske business: structure–function of Rieske non-heme oxygenases DJ Ferraro, L Gakhar, S Ramaswamy Biochemical and biophysical research communications 338 (1), 175-190, 2005 | 422 | 2005 |
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia HP Jia, DC Look, P Tan, L Shi, M Hickey, L Gakhar, MC Chappell, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (1 …, 2009 | 362 | 2009 |
PLUNC is a novel airway surfactant protein with anti-biofilm activity L Gakhar, JA Bartlett, J Penterman, D Mizrachi, PK Singh, RK Mallampalli, ... PloS one 5 (2), e9098, 2010 | 156 | 2010 |
Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia NB Ray, L Durairaj, BB Chen, BJ McVerry, AJ Ryan, M Donahoe, ... Nature medicine 16 (10), 1120-1127, 2010 | 147 | 2010 |
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange BD Freudenthal, L Gakhar, S Ramaswamy, MT Washington Nature structural & molecular biology 17 (4), 479-484, 2010 | 137 | 2010 |
WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins N Pashkova, L Gakhar, SC Winistorfer, L Yu, S Ramaswamy, RC Piper Molecular cell 40 (3), 433-443, 2010 | 132 | 2010 |
Novel, Highly Specific N-Demethylases Enable Bacteria To Live on Caffeine and Related Purine Alkaloids RM Summers, TM Louie, CL Yu, L Gakhar, KC Louie, M Subramanian Journal of bacteriology 194 (8), 2041-2049, 2012 | 117 | 2012 |
The NMDA receptor NR1 C1 region bound to calmodulin: structural insights into functional differences between homologous domains ZA Ataman, L Gakhar, BR Sorensen, JW Hell, MA Shea Structure 15 (12), 1603-1617, 2007 | 115 | 2007 |
The yeast Alix homolog Bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes N Pashkova, L Gakhar, SC Winistorfer, AB Sunshine, M Rich, MJ Dunham, ... Developmental cell 25 (5), 520-533, 2013 | 114 | 2013 |
Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6 HJ Little, NK Rorick, LI Su, C Baldock, S Malhotra, T Jowitt, L Gakhar, ... Human molecular genetics 18 (3), 535-545, 2009 | 114 | 2009 |
SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection Y Liu, JA Bartlett, ME Di, JM Bomberger, YR Chan, L Gakhar, ... The American journal of pathology 182 (5), 1519-1531, 2013 | 112 | 2013 |
Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii Q Guo, L Gakhar, K Wickersham, K Francis, A Vardi-Kilshtain, DT Major, ... Biochemistry 55 (19), 2760-2771, 2016 | 98 | 2016 |
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA SE Tsutakawa, AW Van Wynsberghe, BD Freudenthal, CP Weinacht, ... Proceedings of the National Academy of Sciences 108 (43), 17672-17677, 2011 | 72 | 2011 |
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment TK Ulland, N Jain, EE Hornick, EI Elliott, GM Clay, JJ Sadler, KAM Mills, ... Nature communications 7 (1), 13180, 2016 | 70 | 2016 |
Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase L Gakhar, ZA Malik, CCR Allen, DA Lipscomb, MJ Larkin, S Ramaswamy Journal of bacteriology 187 (21), 7222-7231, 2005 | 64 | 2005 |
Structural basis of phosphodiesterase 6 inhibition by the C‐terminal region of the γ‐subunit B Barren, L Gakhar, H Muradov, KK Boyd, S Ramaswamy, NO Artemyev The EMBO journal 28 (22), 3613-3622, 2009 | 62 | 2009 |
PLUNC: a multifunctional surfactant of the airways J Bartlett, L Gakhar, J Penterman, P Singh, RK Mallampalli, E Porter, ... Biochemical Society Transactions 39 (4), 1012-1016, 2011 | 59 | 2011 |
Mutations in Extracellular Matrix Genes NID1 and LAMC1 Cause Autosomal Dominant Dandy–Walker Malformation and Occipital Cephaloceles BW Darbro, VB Mahajan, L Gakhar, JM Skeie, E Campbell, S Wu, X Bing, ... Human mutation 34 (8), 1075-1079, 2013 | 49 | 2013 |
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ... Human molecular genetics 24 (16), 4584-4598, 2015 | 48 | 2015 |
Structural Modeling of a Novel CAPN5 Mutation that Causes Uveitis and Neovascular Retinal Detachment AG Bassuk, S Yeh, S Wu, DF Martin, SH Tsang, L Gakhar, VB Mahajan PloS one 10 (4), e0122352, 2015 | 46 | 2015 |