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Lokesh Gakhar
Lokesh Gakhar
PAQ Therapeutics
在 uiowa.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Rieske business: structure–function of Rieske non-heme oxygenases
DJ Ferraro, L Gakhar, S Ramaswamy
Biochemical and biophysical research communications 338 (1), 175-190, 2005
4222005
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
HP Jia, DC Look, P Tan, L Shi, M Hickey, L Gakhar, MC Chappell, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (1 …, 2009
3622009
PLUNC is a novel airway surfactant protein with anti-biofilm activity
L Gakhar, JA Bartlett, J Penterman, D Mizrachi, PK Singh, RK Mallampalli, ...
PloS one 5 (2), e9098, 2010
1562010
Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia
NB Ray, L Durairaj, BB Chen, BJ McVerry, AJ Ryan, M Donahoe, ...
Nature medicine 16 (10), 1120-1127, 2010
1472010
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange
BD Freudenthal, L Gakhar, S Ramaswamy, MT Washington
Nature structural & molecular biology 17 (4), 479-484, 2010
1372010
WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins
N Pashkova, L Gakhar, SC Winistorfer, L Yu, S Ramaswamy, RC Piper
Molecular cell 40 (3), 433-443, 2010
1322010
Novel, Highly Specific N-Demethylases Enable Bacteria To Live on Caffeine and Related Purine Alkaloids
RM Summers, TM Louie, CL Yu, L Gakhar, KC Louie, M Subramanian
Journal of bacteriology 194 (8), 2041-2049, 2012
1172012
The NMDA receptor NR1 C1 region bound to calmodulin: structural insights into functional differences between homologous domains
ZA Ataman, L Gakhar, BR Sorensen, JW Hell, MA Shea
Structure 15 (12), 1603-1617, 2007
1152007
The yeast Alix homolog Bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes
N Pashkova, L Gakhar, SC Winistorfer, AB Sunshine, M Rich, MJ Dunham, ...
Developmental cell 25 (5), 520-533, 2013
1142013
Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6
HJ Little, NK Rorick, LI Su, C Baldock, S Malhotra, T Jowitt, L Gakhar, ...
Human molecular genetics 18 (3), 535-545, 2009
1142009
SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection
Y Liu, JA Bartlett, ME Di, JM Bomberger, YR Chan, L Gakhar, ...
The American journal of pathology 182 (5), 1519-1531, 2013
1122013
Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii
Q Guo, L Gakhar, K Wickersham, K Francis, A Vardi-Kilshtain, DT Major, ...
Biochemistry 55 (19), 2760-2771, 2016
982016
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA
SE Tsutakawa, AW Van Wynsberghe, BD Freudenthal, CP Weinacht, ...
Proceedings of the National Academy of Sciences 108 (43), 17672-17677, 2011
722011
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment
TK Ulland, N Jain, EE Hornick, EI Elliott, GM Clay, JJ Sadler, KAM Mills, ...
Nature communications 7 (1), 13180, 2016
702016
Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase
L Gakhar, ZA Malik, CCR Allen, DA Lipscomb, MJ Larkin, S Ramaswamy
Journal of bacteriology 187 (21), 7222-7231, 2005
642005
Structural basis of phosphodiesterase 6 inhibition by the C‐terminal region of the γ‐subunit
B Barren, L Gakhar, H Muradov, KK Boyd, S Ramaswamy, NO Artemyev
The EMBO journal 28 (22), 3613-3622, 2009
622009
PLUNC: a multifunctional surfactant of the airways
J Bartlett, L Gakhar, J Penterman, P Singh, RK Mallampalli, E Porter, ...
Biochemical Society Transactions 39 (4), 1012-1016, 2011
592011
Mutations in Extracellular Matrix Genes NID1 and LAMC1 Cause Autosomal Dominant Dandy–Walker Malformation and Occipital Cephaloceles
BW Darbro, VB Mahajan, L Gakhar, JM Skeie, E Campbell, S Wu, X Bing, ...
Human mutation 34 (8), 1075-1079, 2013
492013
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model
KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ...
Human molecular genetics 24 (16), 4584-4598, 2015
482015
Structural Modeling of a Novel CAPN5 Mutation that Causes Uveitis and Neovascular Retinal Detachment
AG Bassuk, S Yeh, S Wu, DF Martin, SH Tsang, L Gakhar, VB Mahajan
PloS one 10 (4), e0122352, 2015
462015
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