Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability A Umar, CR Boland, JP Terdiman, S Syngal, A Chapelle, J Rüschoff, ... Journal of the National Cancer Institute 96 (4), 261-268, 2004 | 3825 | 2004 |
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma JG Herman, A Umar, K Polyak, JR Graff, N Ahuja, JPJ Issa, S Markowitz, ... Proceedings of the National Academy of Sciences 95 (12), 6870-6875, 1998 | 2442 | 1998 |
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. N Bhala, J Emberson, A Merhi, S Abramson, N Arber, JA Baron, ... Lancet (London, England) 382 (9894), 769-779, 2013 | 1634 | 2013 |
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis A Umar, AB Buermeyer, JA Simon, DC Thomas, AB Clark, RM Liskay, ... Cell 87 (1), 65-73, 1996 | 757 | 1996 |
Meiotic pachytene arrest in MLH1-deficient mice W Edelmann, PE Cohen, M Kane, K Lau, B Morrow, S Bennett, A Umar, ... Cell 85 (7), 1125-1134, 1996 | 717 | 1996 |
Human Chromosome 3 Corrects Mismatch Repair Deficiency and Microsatellite Instability and Reduces N-Methyl-N′-nitro-N-nitrosoguanidine Tolerance in Colon Tumor … M Koi, A Umar, DP Chauhan, SP Cherian, JM Carethers, TA Kunkei, ... Cancer research 54 (16), 4308-4312, 1994 | 634 | 1994 |
Evidence for a Connection between the Mismatch Repair System and the G2 Cell Cycle Checkpoint MT Hawn, A Umar, JM Carethers, G Marra, TA Kunkel, CR Boland, M Koi Cancer Research 55 (17), 3721-3725, 1995 | 493 | 1995 |
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility W Edelmann, K Yang, A Umar, J Heyer, K Lau, K Fan, W Liedtke, ... Cell 91 (4), 467-477, 1997 | 442 | 1997 |
Estimates of benefits and harms of prophylactic use of aspirin in the general population J Cuzick, MA Thorat, C Bosetti, PH Brown, J Burn, NR Cook, LG Ford, ... Annals of Oncology 26 (1), 47-57, 2015 | 440 | 2015 |
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines JC Boyer, A Umar, JI Risinger, JR Lipford, M Kane, S Yin, JC Barrett, ... Cancer research 55 (24), 6063-6070, 1995 | 428 | 1995 |
The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts A Vaisman, M Varchenko, A Umar, TA Kunkel, JI Risinger, JC Barrett, ... Cancer research 58 (16), 3579-3585, 1998 | 424 | 1998 |
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. A Umar, JC Boyer, DC Thomas, DC Nguyen, JI Risinger, J Boyd, Y Ionov, ... Journal of Biological Chemistry 269 (20), 14367-14370, 1994 | 390 | 1994 |
Future directions in cancer prevention A Umar, BK Dunn, P Greenwald Nature Reviews Cancer 12 (12), 835-848, 2012 | 327 | 2012 |
DNA‐replication fidelity, mismatch repair and genome instability in cancer cells A Umar, TA Kunkel European journal of biochemistry 238 (2), 297-307, 1996 | 289 | 1996 |
Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial CA Elmets, JL Viner, AP Pentland, W Cantrell, HY Lin, H Bailey, S Kang, ... Journal of the National Cancer Institute 102 (24), 1835-1844, 2010 | 279 | 2010 |
Testing guidelines for hereditary non-polyposis colorectal cancer A Umar, JI Risinger, ET Hawk, JC Barrett Nature Reviews Cancer 4 (2), 153-158, 2004 | 246 | 2004 |
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair JI Risinger, A Umar, J Boyd, A Berchuck, TA Kunkel, JC Barrett Nature genetics 14 (1), 102-105, 1996 | 223 | 1996 |
Five-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib Trial MM Bertagnolli, CJ Eagle, AG Zauber, M Redston, A Breazna, KM Kim, ... Cancer prevention research 2 (4), 310-321, 2009 | 222 | 2009 |
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression W Edelmann, A Umar, K Yang, J Heyer, M Kucherlapati, M Lia, B Kneitz, ... Cancer research 60 (4), 803-807, 2000 | 217 | 2000 |
Correction of Hypermutability, N-Methyl-N′-nitro-N-nitrosoguanidine Resistance, and Defective DNA Mismatch Repair by Introducing Chromosome 2 into Human Tumor Cells with … A Umar, M Koi, JI Risinger, WE Glaab, KR Tindall, RD Kolodner, ... Cancer research 57 (18), 3949-3955, 1997 | 216 | 1997 |